Blar i Bergen Open Research Archive på forfatter "Heggdal, Jan Ingemann"
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Gamma knife surgery as monotherapy with clinically relevant doses prolongs survival in a Human GBM Xenograft Model
Skeie, Bente Sandvei; Wang, Jian; Dodoo, Ernest; Heggdal, Jan Ingemann; Grønli, Janne; Sleire, Linda; Bragstad, Sidsel Marit; Ganz, Jeremy Christopher; Chekenya, Martha; Mørk, Sverre; Pedersen, Paal-Henning; Enger, Per Øyvind (Peer reviewed; Journal article, 2013)Object. Gamma knife surgery (GKS) may be used for recurring glioblastomas (GBMs). However, patients have then usually undergone multimodal treatment, which makes it difficult to specifically validate GKS independent of ... -
A simple score to estimate the likelihood of pseudoprogression vs. recurrence following stereotactic radiosurgery for brain metastases: The Bergen Criteria
Skeie, Bente Sandvei; Enger, Per Øyvind; Knisely, Jonathan; Pedersen, Paal-Henning; Heggdal, Jan Ingemann; Eide, Geir Egil; Skeie, Geir Olve (Journal article; Peer reviewed, 2020)Background A major challenge in the follow-up of patients treated with stereotactic radiosurgery (SRS) for brain metastases (BM) is to distinguish pseudoprogression (PP) from tumor recurrence (TR). The aim of the study ... -
The styryl benzoic acid derivative DC10 potentiates radiotherapy by targeting the xCT-glutathione axis
Sarowar, Shahin; Cirillo, Davide; Játiva, Pablo; Nilsen, Mette Hartmark; Otragane, Sarah-Muheha Anni; Heggdal, Jan Ingemann; Selheim, Frode; Ceña, Valentín; Bjørsvik, Hans-René; Enger, Per Øyvind (Journal article; Peer reviewed, 2022)Metastatic tumors with moderate radiosensitivity account for most cancer-related deaths, highlighting the limitations of current radiotherapy regimens. The xCT-inhibitor sulfasalazine (SAS) sensitizes cancer cells to ...