Blar i Department of Clinical Science på tidsskrift "Bioinformatics"

Viser treff 1-3 av 3

    • Extending protein interaction networks using proteoforms and small molecules 

      Sanchez, Luis Francisco Hernandez; Burger, Bram; Campos, Rodrigo Alexander Castro; Johansson, Stefan; Njølstad, Pål Rasmus; Barsnes, Harald; Vaudel, Marc (Journal article; Peer reviewed, 2023)
      Motivation: Biological network analysis for high-throughput biomedical data interpretation relies heavily on topological characteristics. Networks are commonly composed of nodes representing genes or proteins that are ...

    • Personal Cancer Genome Reporter: Variant interpretation report for precision oncology 

      Nakken, Sigve; Fournous, Ghislain; Vodak, Daniel; Aasheim, Lars Birger; Myklebost, Ola; Hovig, Eivind (Peer reviewed; Journal article, 2018-05)
      Individual tumor genomes pose a major challenge for clinical interpretation due to their unique sets of acquired mutations. There is a general scarcity of tools that can (i) systematically interrogate cancer genomes in the ...

    • ramr: an R/Bioconductor package for detection of rare aberrantly methylated regions 

      Nikolaienko, Oleksii; Lønning, Per Eystein; Knappskog, Stian (Journal article; Peer reviewed, 2022)
      Motivation: With recent advances in the field of epigenetics, the focus is widening from large and frequent disease- or phenotype-related methylation signatures to rare alterations transmitted mitotically or transgenerationally ...