• High throughput toxicity screening and intracellular detection of nanomaterials 

      Collins, Andrew Richard; Balasubramanyam, Annangi; Rubio, Laura; Marcos, Ricard; Dorn, Marco; Merker, Carolin; Estrela-Lopis, Irina; Cimpan, Mihaela Roxana; Ibrahim, Mohamed; Cimpan, Emil; Ostermann, Melanie; Sauter, Alexander; El Yamani, Naouale; Shaposhnikov, Sergey; Chevillard, Sylvie; Paget, Vincent; Grall, Romain; Delic, Jozo; Goñi- de-Cerio, Felipe; Suarez-Merino, Blanca; Fessard, Valérie; Hogeveen, Kevin N; Fjellsbø, Lise Maria; Runden Pran, Elise; Brzicova, Tana; Topinka, Jan; João Silva, Maria; Leite, PE; Ribeiro, AR; Granjeiro, JM; Grafström, Roland; Prina-Mello, Adriele; Dusinska, Maria (Peer reviewed; Journal article, 2017-01)
      With the growing numbers of nanomaterials (NMs), there is a great demand for rapid and reliable ways of testing NM safety—preferably using in vitro approaches, to avoid the ethical dilemmas associated with animal research. ...
    • Label-free impedance flow cytometry for nanotoxicity screening 

      Ostermann, Melanie; Sauter, Alexander; Xue, Ying; Birkeland, Eivind Salmorin; Schoelermann, Julia; Holst, Bodil; Cimpan, Mihaela Roxana (Peer reviewed; Journal article, 2020)
      The development of reliable and cost-efficient methods to assess the toxicity of nanomaterials (NMs) is critical for the proper identification of their impact on human health and for ensuring a safe progress of nanotechnology. ...
    • Label-free monitoring of uptake and toxicity of endoprosthetic wear particles in human cell cultures 

      Jonitz-Heincke, Anika; Tillmann, Jenny; Ostermann, Melanie; Springer, Armin; Bader, Rainer; Høl, Paul Johan; Cimpan, Mihaela Roxana (Peer reviewed; Journal article, 2018)
      The evaluation of the biological effects of endoprosthetic wear particles on cells in vitro relies on a variety of test assays. However, most of these methods are susceptible to particle-induced interferences; therefore, ...