Now showing items 1-6 of 6

    • Angiogenic and Immunomodulatory Properties of Endothelial and Mesenchymal Stem Cells 

      Bartaula, Sushma; Pedersen, Torbjørn Østvik; Finne-Wistrand, Anna; Bolstad, Anne Isine; Mustafa, Kamal Babikeir Eln (Mary Ann Liebert, 2016-02)
      It has been suggested that the effect of implanted cells on the local environment is important when selecting the appropriate cell type for tissue regeneration. Our aim was to compare the local tissue response to implanted ...
      Journal article
    • Cell seeding density is a critical determinant for copolymer scaffolds-induced bone regeneration 

      Yassin, Mohammed Ahmed; Leknes, Knut N.; Pedersen, Torbjørn Østvik; Xing, Zhe; Sun, Yang; Lie, Stein Atle; Finne-Wistrand, Anna; Mustafa, Kamal Babikeir Eln (Wiley, 2015-11)
      Constructs intended for bone tissue engineering (TE) are influenced by the initial cell seeding density. Therefore, the objective of this study was to determine the effect of bone marrow stromal stem cells (BMSCs) density ...
      Journal article
    • Endothelial microvascular networks affect gene-expression profiles and osteogenic potential of tissue-engineered constructs 

      Pedersen, Torbjørn Østvik; Blois, Anna L; Xing, Zhe; Xue, Ying; Sun, Yang; Finne-Wistrand, Anna; Akslen, Lars A.; Lorens, James B.; Leknes, Knut N.; Fristad, Inge; Mustafa, Kamal Babikeir Eln (BioMed Central, 2013-05-17)
      Introduction: A major determinant of the potential size of cell/scaffold constructs in tissue engineering is vascularization. The aims of this study were twofold: first to determine the in vitro angiogenic and osteogenic ...
      Journal article
    • In vivo host response and degradation of copolymer scaffolds functionalized with nanodiamonds and bone morphogenetic protein 2 

      Suliman, Salwa; Sun, Yang; Pedersen, Torbjørn Østvik; Xue, Ying; Nickel, Joachim; Waag, Thilo; Finne-Wistrand, Anna; Steinmüller-Nethl, Doris; Krueger, Anke; Costea, Daniela Elena; Mustafa, Kamal Babikeir Eln (Wiley, 2016-03)
      The aim is to evaluate the effect of modifying poly[(l-lactide)-co-(ε-caprolactone)] scaffolds (PLCL) with nanodiamonds (nDP) or with nDP+physisorbed BMP-2 (nDP+BMP-2) on in vivo host tissue response and degradation. The ...
      Journal article
    • Mesenchymal stem cells induce endothelial cell quiescence and promote capillary formation 

      Pedersen, Torbjørn Østvik; Blois, Anna L; Xue, Ying; Xing, Zhe; Sun, Yang; Finne-Wistrand, Anna; Lorens, James B.; Fristad, Inge; Leknes, Knut N.; Mustafa, Kamal Babikeir Eln (BioMed Central, 2014-02-17)
      Introduction: Rapid establishment of functional blood vessels is a prerequisite for successful tissue engineering. During vascular development, endothelial cells (ECs) and perivascular cells assemble into a complex ...
      Journal article
    • Release and bioactivity of bone morphogenetic protein-2 are affected by scaffold binding techniques in vitro and in vivo 

      Suliman, Salwa; Xing, Zhe; Wu, X; Xue, Ying; Pedersen, Torbjørn Østvik; Sun, Y; Døskeland, Anne Marie Simonne; Nickel, Joachim; Waag, Thilo; Lygre, Henning; Finne Wistrand, Anna; Steinmüller-Nethl, Doris; Krueger, Anke; Mustafa, Kamal Babikeir Eln (Elsevier, 2015-01-10)
      A low dose of 1 μg rhBMP-2 was immobilised by four different functionalising techniques on recently developed poly(l-lactide)-co-(ε-caprolactone) [(poly(LLA-co-CL)] scaffolds. It was either (i) physisorbed on unmodified ...
      Journal article