Now showing items 1-2 of 2
Prediction of CpG-island function: CpG clustering vs. sliding-window methods
(BioMed Central, 2010-05-26)
Background Unmethylated stretches of CpG dinucleotides (CpG islands) are an outstanding property of mammal genomes. Conventionally, these regions are detected by sliding window approaches using %G + C, CpG observed/expected ...
Genomic features and computational identification of human microRNAs under long-range developmental regulation
(BioMed Central, 2011-05-27)
Background: Recent functional studies have demonstrated that many microRNAs (miRNAs) are expressed by RNA polymerase II in a specific spatiotemporal manner during the development of organisms and play a key role ...