Browsing Department of Informatics by Subject "Normal mode analysis"
Now showing items 1-3 of 3
(Public Library of Science, 2011-09-15)Allosteric regulation involves conformational transitions or fluctuations between a few closely related states, caused by the binding of effector molecules. We introduce a quantity called binding leverage that measures ...Peer reviewedJournal article
(Public Library of Science, 2011-12-08)Conformational changes in allosteric regulation can to a large extent be described as motion along one or a few coherent degrees of freedom. The states involved are inherent to the protein, in the sense that they are ...Peer reviewedJournal article
(BioMed Central, 2014-12-30)Background: Normal mode analysis (NMA) using elastic network models is a reliable and cost-effective computational method to characterise protein flexibility and by extension, their dynamics. Further insight into the ...Journal article