Browsing Department of Informatics by Subject "allosteric regulation"
Now showing items 1-3 of 3
(Public Library of Science, 2011-09-15)Allosteric regulation involves conformational transitions or fluctuations between a few closely related states, caused by the binding of effector molecules. We introduce a quantity called binding leverage that measures ...Peer reviewedJournal article
(Public Library of Science, 2011-12-08)Conformational changes in allosteric regulation can to a large extent be described as motion along one or a few coherent degrees of freedom. The states involved are inherent to the protein, in the sense that they are ...Peer reviewedJournal article
(Oxford University Press, 2011)An important aspect of understanding protein allostery, and of artificial effector design, is the characterization and prediction of substrate- and effector-binding sites. To find binding sites in allosteric enzymes, many ...Journal articlePeer reviewed