dc.contributor.author | Nilsen, Vegard | en_US |
dc.contributor.author | Bakke, Per Sigvald | en_US |
dc.contributor.author | Rohde, Gudrun-Elin | en_US |
dc.contributor.author | Gallefoss, Frode | en_US |
dc.date.accessioned | 2015-12-11T12:56:57Z | |
dc.date.available | 2015-12-11T12:56:57Z | |
dc.date.issued | 2014-11 | |
dc.identifier.issn | 0962-9343 | |
dc.identifier.uri | https://hdl.handle.net/1956/10750 | |
dc.description.abstract | Purpose: To assess health-related quality of life (HRQOL) of subjects at risk of type 2 diabetes undergoing lifestyle intervention, and predictors for improved HRQOL. Methods: The Finnish Diabetes Risk Score was used by general practitioners to identify individuals at risk. Lowintensity interventions with an 18-month follow-up were employed. HRQOL was assessed using the SF-36 at baseline and compared with results from a general Norwegian population survey and further at 6 and 18 months. Simple and multiple linear regression analyses were applied to identify predictors of changes in HRQOL of clinical importance. Results: Two hundred and thirteen participants (50 % women; mean age: 46 years, mean body mass index: 37) were included: 182 returned for 18-month follow-up, of whom 172 completed the HRQOL questionnaire. HRQOL was reduced with clinical significance compared with general Norwegians. The mean changes in HRQOL from the baseline to the follow-up were not of clinical importance. However, one out of three individuals achieved a moderate or large clinical improvement in HRQOL. The best determinant for improved HRQOL was obtained for a composite, clinically significant lifestyle change, i.e. both a weight reduction of at least 5 % and an improvement in exercise capacity of at least 10 %, which was associated with an improvement in five out of the eight SF-36 domains. Conclusion: Subjects at risk of type 2 diabetes report a clinically important reduction in HRQOL compared with general Norwegians. The best predictor of improved HRQOL was a small weight loss combined with a small improvement in aerobic capacity. | en_US |
dc.language.iso | eng | eng |
dc.publisher | Springer | eng |
dc.relation.ispartof | <a href=" http://hdl.handle.net/1956/10898" target="blank"> Lifestyle intervention in patients at risk of type 2 diabetes</a> | |
dc.rights | Attribution CC BY | eng |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0 | eng |
dc.subject | Quality of life | eng |
dc.subject | Type 2 diabetes mellitus | eng |
dc.subject | Prevention | eng |
dc.subject | Lifestyle | eng |
dc.subject | Obesity | eng |
dc.title | Predictors of health-related quality of life changes after lifestyle intervention in persons at risk of type 2 diabetes mellitus | en_US |
dc.type | Peer reviewed | |
dc.type | Journal article | |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | Copyright The Author(s) 2014 | |
dc.identifier.doi | https://doi.org/10.1007/s11136-014-0702-z | |
dc.identifier.cristin | 1178877 | |
dc.source.journal | Quality of Life Research | |
dc.source.40 | 23 | |
dc.source.14 | 9 | |
dc.source.pagenumber | 2585-2593 | |