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    • The dual role of glioma exosomal microRNAs: glioma eliminates tumor suppressor miR-1298-5p via exosomes to promote immunosuppressive effects of MDSCs 

      Qi, Yanhua; Jin, Chuandi; Qiu, Wei; Zhao, Rongrong; Wang, Shaobo; Li, Boyan; Zhang, Zongpu; Guo, Qindong; Zhang, Shouji; Gao, Zijie; Zhao, Shulin; Pan, Ziwen; Fan, Yang; chen, Zihang; Wang, Huizhi; Xu, Jianye; Deng, Lin; Ni, Shilei; Wang, Jian; Xue, Hao; Xue, Fuzhong; Li, Gang (Journal article; Peer reviewed, 2022)
      Clear evidence shows that tumors could secrete microRNAs (miRNAs) via exosomes to modulate the tumor microenvironment (TME). However, the mechanisms sorting specific miRNAs into exosomes are still unclear. In order to study ...

    • Dual-Lobe Reconnection and Horse-Collar Auroras 

      Milan, Stephen Eric; Carter, Jennifer Alyson; Bower, G.E.; Imber, S.M.; Paxton, Larry J.; Anderson, Brian J.; Hairston, Marc; Hubert, Benoit (Journal article; Peer reviewed, 2020)
      We propose a mechanism for the formation of the horse-collar auroral configuration during periods of strongly northward interplanetary magnetic field (IMF), invoking the action of dual-lobe reconnection (DLR). Auroral ...

    • Durable immune responses after BNT162b2 vaccination in home-dwelling old adults 

      Hansen, Lena; Brokstad, Karl Albert; Bansal, Amit; Zhou, Fan; Bredholt, Geir; Onyango, Therese Bredholt; Sandnes, Helene Heitmann; Elyanow, Rebecca; Madsen, Anders; Trieu, Mai Chi; Sævik, Marianne; Søyland, Hanne; Olofsson, Jan Stefan; Vahokoski, Juha; Ertesvåg, Nina Urke; Fjelltveit, Elisabeth Berg; Shafiani, Shahin; Tøndel, Camilla; Chapman, Heidi; Kaplan, Ian; Mohn, Kristin Greve-Isdahl; Langeland, Nina; Cox, Rebecca Jane (Journal article; Peer reviewed, 2023)
      Objectives Elderly are an understudied, high-risk group vulnerable to severe COVID-19. We comprehensively analyzed the durability of humoral and cellular immune responses after BNT162b2 vaccination and SARS-CoV-2 infection ...

    • Durable T-cellular and humoral responses in SARS-CoV-2 hospitalized and community patients 

      Mohn, Kristin Greve-Isdahl; Bredholt, Geir; Zhou, Fan; Madsen, Anders Aasgaard; Onyango, Therese Bredholt; Fjelltveit, Elisabeth Berg; Jalloh, Sarah Larteley Lartey; Brokstad, Karl Albert; Cantoni, Diego; Mayora-Neto, Martin; Temperton, Nigel; Langeland, Nina; Cox, Rebecca Jane (Journal article; Peer reviewed, 2022)
      Background Neutralizing antibodies are important for protection against the pandemic SARS-CoV-2 virus, and long-term memory responses determine the risk of re-infection or boosting after vaccination. T-cellular responses ...

    • Duration of elevated heart rate Is an important predictor of exercise-induced troponin elevation 

      Bjørkavoll-Bergseth, Magnus; Kleiven, Øyunn; Auestad, Bjørn Henrik; Eftestøl, Trygve Christian; Oskal, Kay Raymond; Nygård, Martin; Skadberg, Øyvind; Aakre, Kristin Moberg; Melberg, Tor Harald; Gjesdal, Knut; Ørn, Stein (Journal article; Peer reviewed, 2020)
      Background The precise mechanisms causing cardiac troponin (cTn) increase after exercise remain to be determined. The aim of this study was to investigate the impact of heart rate (HR) on exercise‐induced cTn increase by ...

    • Dust Exposure and Respiratory Health Among Workers in Primary Coffee Processing Factories in Tanzania and Ethiopia 

      Bråtveit, Magne; Abaya, Samson Wakuma; Sakwari, Gloria; Moen, Bente Elisabeth (Journal article; Peer reviewed, 2021)
      Introduction: In primary coffee factories the coffee beans are cleaned and sorted. Studies from the 80- and 90-ties indicated respiratory health effects among the workers, but these results may not represent the present ...

    • Duty to treat and perceived risk of contagion during the COVID-19 pandemic: Norwegian physicians’ perspectives and experiences—a questionnaire survey 

      Isaksson Rø, Karin Elisabet; Magelssen, Morten; Bååthe, Fredrik; Miljeteig, Ingrid; Bringedal, Berit (Journal article; Peer reviewed, 2022)
      Background The COVID-19 pandemic actualised the dilemma of how to balance physicians´ obligation to treat patients and their own perceived risk of being infected. To discuss this in a constructive way we need empirical ...

    • Dwarfs’ Family Relations and Female Dwarfs in Some Medieval Nordic Sources 

      Mikucionis, Ugnius Vizgirda (Journal article; Peer reviewed, 2020)
      In this article, it is argued that the dvergar in Old Norse sources, such as skaldic poetry and the Eddas, contrary to what has often been claimed by previous research, are hardly an all-male race deprived of family life ...

    • Dying for change: A roadmap to refine the fish acute toxicity test after 40 years of applying a lethal endpoint 

      Katsiadaki, Ioanna; Ellis, Tim; Andersen, Linda; Antczak, Philipp; Blaker, Ellen; Burden, Natalie; Fisher, Tom; Green, Christopher; Labram, Briony; Pearson, Audrey; Petersen, Karina; Pickford, Dan; Ramsden, Chris; Rønneseth, Anita; Ryder, Kathy; Sacker, Dominic; Stevens, Chloe; Watanabe, Haruna; Yamamoto, Hiroshi; Sewell, Fiona; Hawkins, Penny; Rufli, Hans; Handy, Richard D.; Maynard, Samuel K.; Jacobs, Miriam (Journal article; Peer reviewed, 2021)
      The fish acute toxicity test (TG203; OECD, 2019) is frequently used and highly embedded in hazard and risk assessment globally. The test estimates the concentration of a chemical that kills 50% of the fish (LC50) over a ...

    • Dynamic Boolean modelling reveals the influence of energy supply on bacterial efflux pump expression 

      Johnston, Iain George; Jabbari, Sara; Kerr, Ryan; Blair, Jessica (Journal article; Peer reviewed, 2022)
      Antimicrobial resistance (AMR) is a global health issue. One key factor contributing to AMR is the ability of bacteria to export drugs through efflux pumps, which relies on the ATP-dependent expression and interaction of ...

    • Dynamic contrast-enhanced MRI shows altered blood–brain barrier function of deep gray matter structures in neuroborreliosis: a case–control study 

      Lindland, Elisabeth Margrete Stokke; Solheim, Anne Marit; Andreassen, Silje; Bugge, Robin Antony Birkeland; Eikeland, Randi; Reiso, Harald; Lorentzen, Åslaug Rudjord; Harbo, Hanne-Cathrin Flinstad; Beyer, Mona Kristiansen; Bjørnerud, Atle (Journal article; Peer reviewed, 2023)
      Background Main aim was assessment of regional blood–brain barrier (BBB) function by dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in patients with neuroborreliosis. Secondary aim was to study the correlation ...

    • Dynamic Functional Connectivity Patterns in Schizophrenia and the Relationship With Hallucinations 

      Weber, Sarah; Johnsen, Erik; Kroken, Rune Andreas; Løberg, Else-Marie; Kandilarova, Sevdalina; Stoyanov, Drozdstoy; Kompus, Kristiina; Hugdahl, Kenneth (Journal article; Peer reviewed, 2020)
      There is a wealth of evidence showing aberrant functional connectivity (FC) in schizophrenia but with considerable variability in findings across studies. Dynamic FC is an extension of traditional static FC, in that such ...

    • Dynamic implications of the biological link between bovine milk and meat production for operationalizing the planetary health diet 

      Kopainsky, Birgit Ursula; Kapmeier, Florian (Journal article; Peer reviewed, 2023)
      The EAT–Lancet planetary health diet (PHD) provides guidelines on a global scale and calls for red meat consumption to be halved. Operational PHD guidelines at country level have yet to be determined. Here we argue that ...

    • Dynamic morphometrics of mucous cells reveal the minimal impact of therapeutic doses of peracetic acid on Atlantic salmon gill health 

      Haddeland, Sindre; Lazado, Carlo C.; Merkin, Grigory; Myre, Ole Jacob; Okubamichael, Mearge; Pedersen, Lars-Flemming; Pittman, Karin (Journal article; Peer reviewed, 2021)
      Mucous cells, the microscopic structural hallmark of mucosal surfaces, are highly responsive to environmental changes. Here we report how the gills of Atlantic salmon (Salmo salar) responded to peracetic acid (PAA), a ...

    • Dynamic Programming on Bipartite Tree Decompositions 

      Jaffke, Lars; Morelle, Laure; Sau, Ignasi; Thilikos, Dimitrios M. (Journal article; Peer reviewed, 2023)
      We revisit a graph width parameter that we dub bipartite treewidth, along with its associated graph decomposition that we call bipartite tree decomposition. Bipartite treewidth can be seen as a common generalization of ...

    • The dynamic response of offshore wind turbines and their sensitivity to wind field models 

      Haaskjold Myrtvedt, Maylinn; Nybø, Astrid; Nielsen, Finn Gunnar (Journal article; Peer reviewed, 2020)
      As the rotor diameter of offshore wind turbines increases, an improved understanding of the structure of the turbulent wind field approaching the rotor is important. Present standards for computing wind loads are resting ...

    • Dynamic Susceptibility Contrast MRI May Contribute in Prediction of Stereotactic Radiosurgery Outcome in Brain Metastases 

      Starck, Lea; Skeie, Bente Sandvei; Moen, Gunnar; Grüner, Renate (Journal article; Peer reviewed, 2022)
      Background Following stereotactic radiosurgery (SRS), predicting treatment response is not possible at an early stage using structural imaging alone. Hence, the current study aims at investigating whether dynamic ...

    • Dynamic switching between intrinsic and extrinsic mode networks as demands change from passive to active processing 

      Riemer, Frank; Gruner, Eli Renate; Beresniewicz, Justyna; Kazimierczak, Katarzyna Anna; Ersland, Lars; Hugdahl, Kenneth (Journal article; Peer reviewed, 2020-12-08)
      In this study we report on the relationship between default and extrinsic mode networks across alternating brief periods of rest and active task processing. Three different visual tasks were used in a classic fMRI ON–OFF ...

    • A dynamic systems analysis of factors affecting success of identity-preserved products: the case of high-oleic soybeans 

      Nicholson, Charles; McRoberts, Keenan; Suleyman Öz, Besir; Kopainsky, Birgit (Journal article; Peer reviewed, 2022)
      The factors contributing to success of identity-preserved (IP) products are understood conceptually, but are rarely quantified. A combination of system dynamics modeling and group modeling building with value chain ...

    • Dynamical drivers of Greenland blocking in climate models 

      Michel, Clio; Madonna, Erica; Spensberger, Clemens; Li, Camille; Outten, Stephen (Journal article; Peer reviewed, 2021)
      Blocking over Greenland is known to lead to strong surface impacts, such as ice sheet melting, and a change in its future frequency can have important consequences. However, as previous studies demonstrated, climate models ...