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Molecular and phenotypic characteristics influencing the degree of cytoreduction in high-grade serous ovarian carcinomas
(Journal article; Peer reviewed, 2023)Background: High-grade serous ovarian carcinoma (HGSOC) is the deadliest ovarian cancer subtype, and survival relates to initial cytoreductive surgical treatment. The existing tools for surgical outcome prediction remain ... -
Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK
(Journal article; Peer reviewed, 2020-02)The human N-terminal acetyltransferase E (NatE) contains NAA10 and NAA50 catalytic, and NAA15 auxiliary subunits and associates with HYPK, a protein with intrinsic NAA10 inhibitory activity. NatE co-translationally acetylates ... -
Molecular Biomarkers in Thyroid Eye Disease: A Literature Review
(Journal article; Peer reviewed, 2023)Purpose: Thyroid eye disease (TED) is the most common extrathyroidal manifestation of Graves disease. Patients may be severely affected with eyelid retraction, exophthalmos, diplopia, pain, and threatened vision. ... -
Molecular characterisation of the first New Delhi metallo-β-lactamase 1-producing Acinetobacter baumannii from Tanzania
(Journal article; Peer reviewed, 2021)Background We aimed to characterise the genetic determinants and context of two meropenem-resistant clinical isolates of Acinetobacter baumannii isolated from children hospitalised with bloodstream infections in Dar es ... -
The molecular characteristics of high-grade gastroenteropancreatic neuroendocrine neoplasms
(Journal article; Peer reviewed, 2021)High-grade (HG) gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) are rare but have a very poor prognosis and represent a severely understudied class of tumours. Molecular data for HG GEP-NEN are limited, and ... -
Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis
(Journal article; Peer reviewed, 2020-01-10)Background: We have reported that BRAF V600E mutations and microsatellite instability-high (MSI-H) are more prevalent in a population-based cohort of metastatic colorectal cancer (mCRC) patients than has been reported from ... -
Molecular characterization of the myoliquefactive fish parasite kudoa mirabilis (Cnidaria, kudoidae) from se Indian Ocean and its phylogenetic relationship with the kudoa thyrsites species complex
(Journal article; Peer reviewed, 2020)Myxosporean parasites of the genus Kudoa are fish parasites of great economic importance, as some species can affect the fish fillet quality by producing macroscopic cysts or generating post mortem myoliquefaction, commonly ... -
The Molecular Epidemiology of Enterovirus in a Birth Cohort in Nepal
(Journal article; Peer reviewed, 2023)Acute gastroenteritis (AGE) has a major impact on morbidity and mortality worldwide. The viral aetiology of diarrhoeal diseases may remain unknown due to limited diagnostic facilities. Non-polio enteroviruses (NPEVs) are ... -
Molecular evidence for a single origin of ultrafiltration-based excretory organs
(Journal article; Peer reviewed, 2021)Excretion is an essential physiological process, carried out by all living organisms, regardless of their size or complexity.1, 2, 3 Both protostomes (e.g., flies and flatworms) and deuterostomes (e.g., humans and sea ... -
Molecular evidence of parallel evolution in a cyanophage
(Journal article; Peer reviewed, 2023)Antagonistic interactions between bacteriophage (phage) and its bacterial host drives the continual selection for resistance and counter-defence. To date, much remains unknown about the genomic evolution that occurs as ... -
Molecular identification and first demographic insights of sharks based on artisanal fisheries bycatch in the Pacific Coast of Colombia: implications for conservation
(Journal article; Peer reviewed, 2022)The Pacific coast of Colombia is characterized by mangrove ecosystems which play a crucial role as possible nurseries for juvenile sharks. However, trophic food webs from coastal ecosystems are heavily disturbed by increased ... -
The Molecular Machinery of Gametogenesis in Geodia Demosponges (Porifera): Evolutionary Origins of a Conserved Toolkit across Animals
(Journal article; Peer reviewed, 2020)All animals are capable of undergoing gametogenesis. The ability of forming haploid cells from diploid cells through meiosis and recombination appeared early in eukaryotes, whereas further gamete differentiation is mostly ... -
Molecular mechanisms governing development of the hindbrain choroid plexus and auditory projection: A validation of the seminal observations of Wilhelm His
(Journal article; Peer reviewed, 2022)Studies by His from 1868 to 1904 delineated the critical role of the dorsal roof plate in the development of the hindbrain choroid plexus, and of the rhombic lips in the development of hindbrain auditory centers. Modern ... -
Molecular oxygen-assisted in defect-rich ZnO for catalytic depolymerization of polyethylene terephthalate
(Journal article; Peer reviewed, 2023)Polyethylene terephthalate (PET) is the most produced polyester plastic; its waste has a disruptive impact on the environment and ecosystem. Here, we report a catalytic depolymerization of PET into bis(2-hydroxyethyl) ... -
Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing
(Journal article, 2021)Objectives Systemic lupus erythematosus (SLE) is an autoimmune disease with extensive heterogeneity in disease presentation between patients, which is likely due to an underlying molecular diversity. Here, we aimed at ... -
A molecular phylogeny of the European nesticid spiders (Nesticidae, Araneae): Implications for their systematics and biogeography
(Journal article; Peer reviewed, 2023)Nesticidae is a small family of spiders with a worldwide distribution that includes 15 genera and 272 described species. Seven genera and 56 species are known from Europe, distributed from the Iberian Peninsula to the ... -
Molecular phylogeny of the marine snail genus Haminoea (Gastropoda, Cephalaspidea): A framework to study marine diversity and speciation
(Journal article; Peer reviewed, 2023)Haminoea are herbivorous, coastal snails occurring in temperate and tropical waters of the Atlantic and Eastern Pacific oceans, with one species present in temperate South Africa (Indian Ocean). The genus is taxonomically ... -
Molecular systematics of the long-snouted deep water dogfish (Centrophoridae, Deania) with implications for identification, taxonomy and conservation.
(Journal article; Peer reviewed, 2021-01-20)According to the most recent taxonomical revision, the deep-sea dogfish genus Deania encompasses four species. Three of them, D. calcea, D. profundorum, and D. hystricosa, occur in the North Atlantic. Whilst D. profundorum ... -
Moments of fun: Narratives of children’s experiences of music therapy in mental health care
(Journal article; Peer reviewed, 2023)Introduction Mental health issues in children involve complexities and life challenges for the child and their families. Music therapy as part of treatment in mental health care focuses on interaction and communication ... -
Monastic Readings of the Nag Hammadi Codices
(Chapter, 2023)