Browsing University of Bergen Library by Title

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    • Human blood serum proteome changes after 6 hours of sleep deprivation at night 

      Bjørkum, Alvhild Alette; Duran, Ana Carasco; Berven, Frode Steingrimsen; Roy, Dola Sinha; Rosendahl, Karen; Birkeland, Even; Stuhr, Linda Elin Birkhaug (Journal article; Peer reviewed, 2021)
      Background The aim of this study was to discover significantly changed proteins in human blood serum after loss of 6 h sleep at night. Furthermore, to reveal affected biological process- and molecular function categories ...

    • The human dimension of biodiversity changes on islands 

      Nogué, Sandra; Santos, Ana; Birks, Harry John Betteley; Björck, Svante; Castilla-Beltrán, Alvaro; Connor, Simon; de Boer, Erik J.; de Nascimento, Lea; Felde, Vivian Astrup; Fernández-Palacios, José María; Froyd, Cynthia; Haberle, Simon G.; Hooghiemstra, Henry; Ljung, Karl; Norder, Sietze J.; Peñuelas, Josep; Prebble, Matthew; Stevenson, Janelle; Whittaker, Robert J.; Willis, Kathy J.; Wilmshurst, Janet M.; Steinbauer, Manuel (Journal article; Peer reviewed, 2021)
      Islands are among the last regions on Earth settled and transformed by human activities, and they provide replicated model systems for analysis of how people affect ecological functions. By analyzing 27 representative ...

    • Human footprints provide snapshot of last interglacial ecology in the Arabian interior 

      Stewart, Mathew; Clark-Wilson, Richard; Breeze, Paul S; Janulis, Klint; Candy, Ian; Armitage, Simon James; Ryves, David B.; Louys, Julien; Duval, Mathieu; Price, Gilbert J; Cuthbertson, Patrick; Bernal, Marco A.; Drake, Nick A; Alsharekh, Abdullah; Zahrani, Badr; Al-Omari, Abdulaziz; Roberts, Patrick; Groucutt, Huw S.; Petraglia, Michael D. (Journal article; Peer reviewed, 2020)
      The nature of human dispersals out of Africa has remained elusive because of the poor resolution of paleoecological data in direct association with remains of the earliest non-African people. Here, we report hominin and ...

    • Human gain-of-function variants in HNF1A confer protection from diabetes but independently increase hepatic secretion of atherogenic lipoproteins 

      DeForest, Natalie; Kavitha, Babu; Hu, Siqi; Isaac, Roi; Krohn, Lynne; Wang, Minxian; Du, Xiaomi; De Arruda Saldanha, Camila; Gylys, Jenny; Merli, Edoardo; Abagyan, Ruben; Najmi, Laeya Abdoli; Mohan, Viswanathan; Flannick, Jason; Peloso, Gina M.; Gordts, Philip L.S.M.; Heinz, Sven; Deaton, Aimee M.; Khera, Amit V.; Olefsky, Jerrold; Radha, Venkatesan; Majithia, Amit R. (Journal article; Peer reviewed, 2023)
      Loss-of-function mutations in hepatocyte nuclear factor 1A (HNF1A) are known to cause rare forms of diabetes and alter hepatic physiology through unclear mechanisms. In the general population, 1:100 individuals carry a ...

    • Human gingival epithelial cells stimulate proliferation, migration, and tube formation of lymphatic endothelial cells in vitro 

      Indrelid, Stine Hufthammer; Dongre, Harsh Nitin; Nunes, Ivana Pereira; Virtej, Anca; Bletsa, Athanasia; Berggreen, Ellen (Journal article; Peer reviewed, 2023)
      Objective The aim of this study was to investigate the response of gingival epithelial cells to microbial and inflammatory signals. Background The gingival epithelial barrier provides the first line of defense and ...

    • Human intracranial pulsatility during the cardiac cycle: a computational modelling framework 

      Causemann, Marius; Vinje, Vegard; Rognes, Marie Elisabeth (Journal article; Peer reviewed, 2022)
      Background Today’s availability of medical imaging and computational resources set the scene for high-fidelity computational modelling of brain biomechanics. The brain and its environment feature a dynamic and complex ...

    • A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia 

      Szabo, Attila; Akkouh, Ibrahim Ahmed; Vandenberghe, Matthieu; Osete, Jordi Requena; Hughes, Timothy; Heine, Vivi M.; Smeland, Olav Bjerkehagen; Glover, Joel Clinton; Andreassen, Ole; Djurovic, Srdjan (Journal article; Peer reviewed, 2021)
      While neurodevelopmental abnormalities have been associated with schizophrenia (SCZ), the role of astroglia in disease pathophysiology remains poorly understood. In the present study, we used a human induced pluripotent ...

    • Human Leukocyte Antigen alleles associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) 

      Lande, Asgeir; Fluge, Øystein; Strand, Elin Bolle; Flåm, Siri Tennebø; Sosa, Daisy Duarte; Mella, Olav; Egeland, Torstein; Saugstad, Ola Didrik; Lie, Benedicte Alexandra; Viken, Marte K (Journal article; Peer reviewed, 2020)
      The etiology and pathogenesis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) are unknown, and autoimmunity is one of many proposed underlying mechanisms. Human Leukocyte Antigen (HLA) associations are ...

    • Human mucosal IgA immune responses against enterotoxigenic escherichia coli 

      Riaz, Saman; Steinsland, Hans; Hanevik, Kurt (Journal article; Peer reviewed, 2020-08-29)
      Infection with enterotoxigenic Escherichia coli (ETEC) is a major contributor to diarrheal illness in children in low- and middle-income countries and travelers to these areas. There is an ongoing effort to develop vaccines ...

    • Human myelin protein P2: from crystallography to time-lapse membrane imaging and neuropathy-associated variants 

      Uusitalo, Maiju; Klenow, Martin Berg; Laulumaa, Saara; Blakeley, Matthew P.; Simonsen, Adam Cohen; Ruskamo, Salla; Kursula, Petri (Journal article; Peer reviewed, 2021)
      Peripheral myelin protein 2 (P2) is a fatty acid-binding protein expressed in vertebrate peripheral nervous system myelin, as well as in human astrocytes. Suggested functions of P2 include membrane stacking and lipid ...

    • Human myelin proteolipid protein structure and lipid bilayer stacking 

      Ruskamo, Salla; Raasakka, Arne; Pedersen, Jan Skov; Martel, Anne; Škubník, Karel; Darwish, Tamim; Porcar, Lionel; Kursula, Petri (Journal article; Peer reviewed, 2022)
      The myelin sheath is an essential, multilayered membrane structure that insulates axons, enabling the rapid transmission of nerve impulses. The tetraspan myelin proteolipid protein (PLP) is the most abundant protein of ...

    • Human NAA30 can rescue yeast mak3∆ mutant growth phenotypes 

      Drazic, Adrian; Varland, Sylvia (Journal article; Peer reviewed, 2021)
      N-terminal acetylation is an irreversible protein modification that primarily occurs co-translationally, and is catalyzed by a highly conserved family of N-terminal acetyltransferases (NATs). The NatC complex (NAA30–NAA35–NAA38) ...

    • Human organotypic airway and lung organoid cells of bronchiolar and alveolar differentiation are permissive to infection by influenza and SARS-CoV-2 respiratory virus 

      Ekanger, Camilla Tvedt; Zhou, Fan; Bohan, Dana; Lotsberg, Maria Lie; Ramnefjell, Maria; Hoareau, Laurence; Røsland, Gro Vatne; Lu, Ning; Aanerud, Marianne; Gärtner, Fabian; Salminen, Pirjo-Riitta; Bentsen, Mariann; Halvorsen, Thomas; Ræder, Helge; Akslen, Lars Andreas; Langeland, Nina; Brokstad, Rebecca Jane Cox; Maury, Wendy; Stuhr, Linda Elin Birkhaug; Lorens, James; Engelsen, Agnete Svendsen Tenfjord (Journal article; Peer reviewed, 2022)
      The ongoing coronavirus disease 2019 (COVID-19) pandemic has led to the initiation of unprecedented research efforts to understand the pathogenesis mediated by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). ...

    • Human Rights and the Broken World 

      Tomalty, Jesse (Journal article; Peer reviewed, 2014)

    • Human seroprevalence of antibodies to tick-borne microbes in southern Norway 

      Thortveit, Erik Thomas; Aase, Audun; Petersen, Lizette Balle; Lorentzen, Åslaug Rudjord; Mygland, Åse; Ljøstad, Unn (Journal article; Peer reviewed, 2020)
      The tick Ixodes ricinus is widespread along the coastline of southern Norway, but data on human exposure to tick-borne microbes are scarce. We aimed to assess the seroprevalence of IgG antibodies to various tick-borne ...

    • The Human Version 2.0: AI, Humanoids, and Immortality 

      Eriksen, Annelin (Journal article; Peer reviewed, 2021)
      This article investigates new ethnography on AI development relating to imaginaries of technoscientific forms of immortality. As a Think Piece in Analytics, it engages in a somewhat experimental comparative endeavor as I ...

    • Human-water dynamics and their role for seasonal water scarcity – a case study 

      Lindqvist, Andreas; Fornell, Rickard; Prade, Thomas; Tufvesson, Linda; Khalil, Sammar; Kopainsky, Birgit (Journal article; Peer reviewed, 2021)
      Ensuring sustainable management and an adequate supply of freshwater resources is a growing challenge around the world. Even in historically water abundant regions climate change together with population growth and economic ...

    • The Humanities of Contagion: How Literary and Visual Representations of the "Spanish" Flu Pandemic Complement, Complicate and Calibrate COVID-19 Narratives 

      Welang, Nahum (Journal article; Peer reviewed, 2023)
      My article examines how literary and visual representations of the “Spanish” Flu contagion foreshadow and generate critical discourses about pandemics. D.H. Lawrence’s novella The Fox characterises paranoia about biological ...

    • Humanized Ovarian Cancer Patient-Derived Xenografts for Improved Preclinical Evaluation of Immunotherapies 

      Kleinmanns, Katrin; Gullaksen, Stein-Erik; Bredholt, Geir; Davidson, Ben; Torkildsen, Cecilie Fredvik; Grindheim, Sindre; Bjørge, Line; Cormack, Emmet Mc (Journal article; Peer reviewed, 2022)
      High-grade serous ovarian cancer (HGSOC) has poor prognosis and new treatment modalities are needed. Immunotherapy, with checkpoint inhibitors, have demonstrated limited impact. To evaluate the suitability for immunotherapeutics, ...

    • “Humans bring food to their mouths, animals bring their mouths to food”—The morality politics of school-lunch sporks in 1970s Japan 

      Hopson, Nathan Edwin (Journal article; Peer reviewed, 2023)
      We are not only what we eat, but how. This article examines the 1970s’ morality politics of spork usage that accompanied the rollout of rice in school lunches. I argue that these discourses about the material culture and ...