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dc.contributor.authorWehling, Eike
dc.contributor.authorNæss, Halvor
dc.contributor.authorWollschlaeger, Daniel
dc.contributor.authorHofstad, Håkon
dc.contributor.authorBramerson, Annika
dc.contributor.authorBende, Mats
dc.contributor.authorNordin, Steven
dc.date.accessioned2016-06-29T11:53:51Z
dc.date.available2016-06-29T11:53:51Z
dc.date.issued2015-10-12
dc.identifier.citationBMC Neurology. 2015 Oct 12;15(1):199eng
dc.identifier.urihttp://hdl.handle.net/1956/12220
dc.description.abstractBackground The aim of the study was to investigate odor identification performance in patients one year after hospital admittance due to stroke. Predictors for olfactory dysfunction were investigated as well as self-reported olfactory function and pleasantness of olfactory items. Methods A 1-year prospective study was performed. Stroke location, classification and comorbidities were registered at hospital admission. One year after admission, olfactory function was assessed using standardized olfactory methods (screening for loss of detection sensitivity and an odor identification test). A group of matched controls was derived from a population-based study to compare odor identification performance between groups. Patients were asked for their personal judgment regarding their olfactory function and pleasantness of odorous items. In addition, global cognitive function and symptoms of depression were assessed. Results A total of 78 patients were enrolled (46 males, 32 females; mean age 68 years) of which 28.2 % exhibited reduced olfactory function (hyposmia) and 15.4 % exhibited loss of olfactory function (10.3 % functional anosmia, 5.1 % complete anosmia). Patients showed significantly lower olfactory performance compared to age- and sex-mated matched controls. Predictors of impaired olfactory function were age and NIHSS score. Self-reports indicated no significant differences between patients with normal olfactory function and those with reduced function. Yet, patients having an olfactory dysfunction rated odorous items as significantly less pleasant compared to patients without dysfunction. Conclusions Olfactory dysfunction seems to occur frequently after stoke even one year after initial admission. The deficits seem to relate to hyposmia and functional anosmia, and less to a complete loss of smell sensitivity.eng
dc.language.isoengeng
dc.publisherBioMed Centraleng
dc.rightsAttribution CC BY 4.0eng
dc.rights.urihttp://creativecommons.org/licenses/by/4.0eng
dc.subjectOlfactioneng
dc.subjectStrokeeng
dc.subjectOdor identificationeng
dc.titleOlfactory dysfunction in chronic stroke patientseng
dc.typeJournal articleeng
dc.date.updated2016-02-24T12:58:32Z
dc.language.rfc3066en
dc.rights.holderCopyright Wehling et al. 2015eng
dc.type.versionpublishedVersioneng
bora.peerreviewedPeer reviewedeng
dc.identifier.doi10.1186/s12883-015-0463-5eng
noa.nsiVDP::Medisinske Fag: 700eng


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Attribution CC BY 4.0
Except where otherwise noted, this item's license is described as Attribution CC BY 4.0