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dc.contributor.authorLindsay, Briannaen_US
dc.contributor.authorOundo, Joseph O.en_US
dc.contributor.authorHossain, Mohammad Anowaren_US
dc.contributor.authorAntonio, Martinen_US
dc.contributor.authorTamboura, Boubouen_US
dc.contributor.authorWalker, Alan W.en_US
dc.contributor.authorPaulson, Joseph N.en_US
dc.contributor.authorParkhill, Julianen_US
dc.contributor.authorOmore, Richarden_US
dc.contributor.authorFaruque, Abu Syed Golamen_US
dc.contributor.authorDas, Suman Kumaren_US
dc.contributor.authorIkumapayi, Usman Nurudeenen_US
dc.contributor.authorAdeyemi, Mitchellen_US
dc.contributor.authorSanogo, Dohen_US
dc.contributor.authorSaha, Debasishen_US
dc.contributor.authorSow, Samba O.en_US
dc.contributor.authorFarag, Tamer H.en_US
dc.contributor.authorNasrin, Dilrubaen_US
dc.contributor.authorLi, Shanen_US
dc.contributor.authorPanchalingam, Sandraen_US
dc.contributor.authorLevine, Myron M.en_US
dc.contributor.authorKotloff, Karenen_US
dc.contributor.authorMagder, Laurence S.en_US
dc.contributor.authorHungerford, Laura L.en_US
dc.contributor.authorSommerfelt, Halvoren_US
dc.contributor.authorPop, Mihaien_US
dc.contributor.authorNataro, James Paulen_US
dc.contributor.authorStine, Oscar Colinen_US
dc.date.accessioned2016-08-05T09:14:08Z
dc.date.available2016-08-05T09:14:08Z
dc.date.issued2015
dc.PublishedEmerging Infectious Diseases 2015, 21(2):242-250eng
dc.identifier.issn1080-6059
dc.identifier.urihttps://hdl.handle.net/1956/12466
dc.description.abstractPathogens in the gastrointestinal tract exist within a vast population of microbes. We examined associations between pathogens and composition of gut microbiota as they relate to Shigella spp./enteroinvasive Escherichia coli infection. We analyzed 3,035 stool specimens (1,735 nondiarrheal and 1,300 moderate-to-severe diarrheal) from the Global Enteric Multicenter Study for 9 enteropathogens. Diarrheal specimens had a higher number of enteropathogens (diarrheal mean 1.4, nondiarrheal mean 0.95; p<0.0001). Rotavirus showed a negative association with Shigella spp. in cases of diarrhea (odds ratio 0.31, 95% CI 0.17–0.55) and had a large combined effect on moderate-to-severe diarrhea (odds ratio 29, 95% CI 3.8–220). In 4 Lactobacillus taxa identified by 16S rRNA gene sequencing, the association between pathogen and disease was decreased, which is consistent with the possibility that Lactobacillus spp. are protective against Shigella spp.–induced diarrhea. Bacterial diversity of gut microbiota was associated with diarrhea status, not high levels of the Shigella spp. ipaH gene.en_US
dc.language.isoengeng
dc.publisherCenters for Disease Control and Preventioneng
dc.titleMicrobiota that affect risk for shigellosis in children in low-income countriesen_US
dc.typePeer reviewed
dc.typeJournal article
dc.date.updated2016-04-07T12:49:13Z
dc.description.versionpublishedVersionen_US
dc.rights.holderEmerging Infectious Diseases is published by the Centers for Disease Control and Prevention, a U.S. Government agency. Therefore, materials published in Emerging Infectious Diseases, including text, figures, tables, and photographs are in the public domain and can be reprinted or used without permission with proper citation.
dc.identifier.doihttps://doi.org/10.3201/eid2102.140795
dc.identifier.cristin1249363
dc.subject.nsiVDP::Medisinske fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801
dc.subject.nsiVDP::Midical sciences: 700::Health sciences: 800::Community medicine, social medicine: 801


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