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Seroprevalence of antibodies to tick-borne encephalitis virus and Anaplasma phagocytophilum in healthy adults from western Norway

Type
Journal article
Peer reviewed
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Date
2015
Author
Hjetland, Reidar
Henningsson, Anna J.
Vainio, Kirsti
Dudman, Susanne Gjeruldsen
Grude, Nils
Ulvestad, Elling
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Abstract

The aim of this study was to assess the seroprevalence of antibodies to tick-borne encephalitis virus (TBEV) and Anaplasma phagocytophilum in a healthy adult population from Sogn and Fjordane county in western Norway. Sera from 1, 213 blood donors were analysed for IgG-antibodies to TBEV, and a random subgroup of 301 donors for IgG to A. phagocytophilum.

In the TBEV ELISA, five (0.4%) sera were positive. These were all interpreted as “false” positives, as four had received vaccines against flaviviruses, and the remaining was negative for neutralizing antibodies to TBEV.

Antibodies to A. phagocytophilum were detected by indirect immunofluorescence in 49 (16.2%) subjects (titer range 80-1280).

The results indicate that TBE currently is not endemic in this part of western Norway. However, there is serological evidence of the existence of human granulocytic anaplasmosis in the population.

Is part of
Tick-borne infections in Sogn og Fjordane, western Norway. Seroprevalence, risk factors and subjective health complaints in blood donors
URI
http://hdl.handle.net/1956/16946
DOI
10.3109/00365548.2014.959044
Citation
Infectious Diseases, 47 (1)p. 52 -56
Publisher
Taylor & Francis
Subject
Tick-borne encephalitis virusAnaplasma phagocytophilumseroprevalenceNorwayblood donors
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  • Department of Clinical Science 461
Copyright 2014 Informa Healthcare

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