dc.contributor.author | Chowdhury, Ranadip | en_US |
dc.contributor.author | Taneja, Sunita | en_US |
dc.contributor.author | Bhandari, Nita | en_US |
dc.contributor.author | Kvestad, Ingrid | en_US |
dc.contributor.author | Strand, Tor A | en_US |
dc.contributor.author | Bhan, Maharaj Kishan | en_US |
dc.date.accessioned | 2018-08-10T12:50:44Z | |
dc.date.available | 2018-08-10T12:50:44Z | |
dc.date.issued | 2017-09-18 | |
dc.Published | Chowdhury, Taneja S, Bhandari N, Kvestad I, Strand TA, Bhan MK. Vitamin-D status and neurodevelopment and growth in young north Indian children: a secondary data analysis. Nutrition Journal. 2017;16:59 | eng |
dc.identifier.issn | 1475-2891 | |
dc.identifier.uri | https://hdl.handle.net/1956/18039 | |
dc.description.abstract | Background: Vitamin-D deficiency has been linked with impaired development in animal studies; however, the evidence from human studies is scanty. Evidence as to whether vitamin-D deficiency during early childhood affects growth is also limited and conflicting. We examined the extent to which vitamin-D deficiency (<10 ng/ml) is associated with neurodevelopment and physical growth in young children. Methods: We used data from a randomized controlled trial (RCT) of daily folic acid and/ or vitamin B12 supplementation for six months in children aged 6 to 30 months conducted in Delhi, India. We measured vitamin-D status and neurodevelopment by the Ages and Stages Questionnaire-3 (ASQ-3) at 12 to 36 months of age. Multiple logistic and linear regressions were used to examine the association between vitamin-D deficiency at baseline and neurodevelopment and growth 6 months follow-up. Results: 25-hydroxy-vitamin-D (25OHD) concentration was measured at baseline for 960 (96%) children. Of these, 331 (34.5%) children were vitamin-D deficient. The total and subscale (except for the Personal social scale) ASQ-3 scores, were not different between the vitamin-D deficient and non-deficient children. Vitamin-D deficiency was also not associated with physical growth at baseline and at follow -up. Conclusion: Our data do not support the hypothesis that vitamin-D deficiency is associated with poor growth and neurodevelopment. | en_US |
dc.language.iso | eng | eng |
dc.publisher | BioMed Central | eng |
dc.rights | Attribution CC BY | eng |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0 | eng |
dc.subject | Vitamin-D | eng |
dc.subject | ASQ-3 | eng |
dc.subject | Neurodevelopment | eng |
dc.subject | Physical growth | eng |
dc.subject | Young north Indian children | eng |
dc.title | Vitamin-D status and neurodevelopment and growth in young north Indian children: a secondary data analysis | en_US |
dc.type | Peer reviewed | |
dc.type | Journal article | |
dc.date.updated | 2018-03-06T13:31:34Z | |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | Copyright 2017 The Author(s) | |
dc.identifier.doi | https://doi.org/10.1186/s12937-017-0285-y | |
dc.identifier.cristin | 1499037 | |
dc.source.journal | Nutrition Journal | |
dc.relation.project | Helse Sør-Øst RHF: 2012090 | |
dc.relation.project | Norges forskningsråd: 223269 | |