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dc.contributor.authorFrisch, Kathleen Marie
dc.contributor.authorSmåge, Sverre Bang
dc.contributor.authorVallestad, Camilla
dc.contributor.authorBrevik, Øyvind Jakobsen
dc.contributor.authorKlevan, Are
dc.contributor.authorOlsen, Rolf Hetlelid
dc.contributor.authorSjaatil, Stine
dc.contributor.authorGauthier, David
dc.contributor.authorBrudeseth, Bjørn Erik
dc.contributor.authorNylund, Are
dc.date.accessioned2019-01-14T10:44:46Z
dc.date.available2019-01-14T10:44:46Z
dc.date.issued2018-08
dc.identifier.issn0140-7775en_US
dc.identifier.urihttps://hdl.handle.net/1956/18882
dc.description.abstractMouthrot, or bacterial stomatitis, is a disease which mainly affects farmed Atlantic salmon, (Salmo salar, L.), smolts recently transferred into salt water in both British Columbia (BC), Canada, and Washington State, USA. It is a significant fish welfare issue which results in economic losses due to mortality and antibiotic treatments. The associated pathogen is Tenacibaculum maritimum, a bacterium which causes significant losses in many species of farmed fish worldwide. This bacterium has not been proven to be the causative agent of mouthrot in BC despite being isolated from affected Atlantic salmon. In this study, challenge experiments were performed to determine whether mouthrot could be induced with T. maritimum isolates collected from outbreaks in Western Canada and to attempt to develop a bath challenge model. A secondary objective was to use this model to test inactivated whole‐cell vaccines for T. maritimum in Atlantic salmon smolts. This study shows that T. maritimum is the causative agent of mouthrot and that the bacteria can readily transfer horizontally within the population. Although the whole‐cell oil‐adjuvanted vaccines produced an antibody response that was partially cross‐reactive with several of the T. maritimum isolates, the vaccines did not protect the fish under the study's conditions.en_US
dc.language.isoengeng
dc.publisherWileyen_US
dc.rightsAttribution CC BYeng
dc.rights.urihttp://creativecommons.org/licenses/by/4.0eng
dc.subjectchallenge modeleng
dc.subjectcohabitationeng
dc.subjectexperimental modeleng
dc.subjectPacific Northwesteng
dc.subjectSalmo Salareng
dc.titleExperimental induction of mouthrot in Atlantic salmon smolts using Tenacibaculum maritimum from Western Canadaen_US
dc.typePeer reviewed
dc.typeJournal article
dc.description.versionpublishedVersionen_US
dc.rights.holderCopyright 2018 The Author(s)en_US
dc.identifier.doihttps://doi.org/10.1111/jfd.12818
dc.identifier.cristin1649480
dc.source.journalJournal of Fish Diseases
dc.source.4041
dc.source.148
dc.source.pagenumber1247-1258


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