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dc.contributor.authorFlak, Marianne Møretrøen_US
dc.contributor.authorHol, Haakon Ramslanden_US
dc.contributor.authorHernes, Susanne M Sen_US
dc.contributor.authorChang, Lindaen_US
dc.contributor.authorEngvig, Andreasen_US
dc.contributor.authorBjuland, Knut Jørgenen_US
dc.contributor.authorPripp, Are Hugoen_US
dc.contributor.authorMadsen, Bengt-Oveen_US
dc.contributor.authorKnapskog, Anne Britaen_US
dc.contributor.authorUlstein, Ingunen_US
dc.contributor.authorLona, Trine Eli.B.en_US
dc.contributor.authorSkranes, Jon Sverreen_US
dc.contributor.authorLøhaugen, Groen_US
dc.date.accessioned2019-11-12T15:00:31Z
dc.date.available2019-11-12T15:00:31Z
dc.date.issued2019-04-12
dc.PublishedFlak MM, Hol HR, Hernes SS, Chang L, Engvig A, Bjuland KJ, Pripp Ah, Madsen B, Knapskog AB, Ulstein I, Lona Te, Skranes J, Løhaugen GCC. Adaptive computerized working memory training in patients with mild cognitive impairment. A randomized double-blind active controlled trial. Frontiers in Psychology. 2019;10:807.eng
dc.identifier.issn1664-1078
dc.identifier.urihttps://hdl.handle.net/1956/20987
dc.description.abstractObjective: We investigated if a 5-week computerized adaptive working memory training program (Cogmed®) of 20 to 25 sessions would be effective in improving the working memory capacity and other neuropsychological functions compared to a non-adaptive working memory training program (active-controlled) in adult patients with mild cognitive impairment (MCI). Methods: This randomized double-blinded active control trial included 68 individuals aged 43 to 88 years, 45 men and 23 women, who were diagnosed with MCI at four Memory clinics. The study sample was randomized by block randomization to either adaptive or non-adaptive computerized working memory training. All participants completed the training, and were assessed with a comprehensive neuropsychological test battery before the intervention, and at 1 and 4 months after training. Results: Compared to the non-adaptive training group, the adaptive training group did not show significantly greater improvement on the main outcome of working memory performance at 1 and 4 months after training. Conclusion: No difference were found between the two types of training on the primary outcome of working memory, or on secondary outcomes of cognitive function domains, in this sample of MCI patients. Hence, the hypothesis that the adaptive training program would lead to greater improvements compared to the non-adaptive training program was not supported. Within group analyses was not performed due to the stringent RCT design.en_US
dc.language.isoengeng
dc.publisherFrontiers Mediaeng
dc.rightsAttribution CC BY 4.0eng
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/eng
dc.subjectComputerized cognitive trainingeng
dc.subjectWorking memoryeng
dc.subjectMild cognitive impairment (MCI)eng
dc.subjectNeuropsychological outcomeseng
dc.subjectRandomized controlled trial (RCT)eng
dc.titleAdaptive computerized working memory training in patients with mild cognitive impairment. A randomized double-blind active controlled trialen_US
dc.typePeer reviewed
dc.typeJournal article
dc.date.updated2019-09-26T11:17:00Z
dc.description.versionpublishedVersionen_US
dc.rights.holderCopyright 2019 Flak, Hol, Hernes, Chang, Engvig, Bjuland, Pripp, Madsen, Knapskog, Ulstein, Lona, Skranes and Løhaugen.
dc.identifier.doihttps://doi.org/10.3389/fpsyg.2019.00807
dc.identifier.cristin1706367
dc.source.journalFrontiers in Psychology


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