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dc.contributor.authorJustad, Sigrid Ravnsborgeng
dc.date.accessioned2010-09-24T07:45:18Z
dc.date.available2010-09-24T07:45:18Z
dc.date.issued2010-05-27eng
dc.date.submitted2010-06-02eng
dc.identifier.urihttp://hdl.handle.net/1956/4201
dc.description.abstractMathematical modeling of physiological fluid systems is regarded as an important tool for further understanding of circulatory properties. The interstitium is a fluid filled space outside the cells in the body, and all transport of substances in and out of cells must pass through the interstitium. It is therefore of great interest to obtain a better understanding of this fluid flow. Large substances, e.g.\ proteins and some therapeutic agents, are hindered due to their molecular size. They are excluded from a certain fraction of the fluid volume, and thus have a lower distribution volume in the interstitium. However, the molecular charge may have a strong influence on the exclusion phenomenon. This has been the motivation for the modeling in this thesis. First, it is derived a set of equations appropriate for modeling fluid flow through the interstitium. Furthermore, a thorough study of electrostatic properties of the interstitium has been performed.en
dc.format.extent1435444 byteseng
dc.format.mimetypeapplication/pdfeng
dc.language.isoengeng
dc.publisherThe University of Bergeneng
dc.titleA Dense Gas Model of Combined Transports and Distributions of Solutes in the Interstitium including Steric and Electrostatic Exclusion Effects, and Comparison with Experimental Dataeng
dc.typeMaster thesiseng
dc.type.degreeMaster i Anvendt og beregningsorientert matematikknob
dc.type.courseMAB399eng
dc.subject.nsiVDP::Matematikk og Naturvitenskap: 400::Matematikk: 410::Anvendt matematikk: 413nob
dc.subject.archivecodeMastergradeng
dc.subject.nus753109eng
dc.type.programMAMN-MABeng
dc.rights.holderCopyright the author. All rights reserved
dc.rights.holderThe authoreng


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