Browsing Centre for Pharmacy by Title
Now showing items 10-29 of 65
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Determination of conformations adopted by CXCR4 and CCR5 at the cell surface
(The University of Bergen, 2010-05-20)The chemokines and their receptors constitute many important physiological functions in the human body. The chemokine receptors belong to the family of G-protein coupled receptors, characterized by 7 α-helices penetrating ...Master thesis -
Diflubenzuron in Atlantic Cod (Gadus morhua) - Multiple Dose Pharmacokinetic Study
(The University of Bergen, 2012-05-21)Diflubenzuron, a chitin synthesis inhibitor, is used as a parasiticide against sea lice in farmed salmonids. It is administered orally via medicated feed pellets. Due to low bioavailability and biliary secretion of the ...Master thesis -
Evaluation of the sublingual route for administration of influenza vaccines in a murine model
(The University of Bergen, 2011-05-19)Influenza is a one of the most important respiratory viruses, and it infects millions of people every year. Due to mutational changes in the virus genome (antigenic drift), influenza cause occasional pandemics. Pandemic ...Master thesis -
Evaluering av pilotprosjektet Trygg Mammamedisin -en kvantitativ og kvalitativ studie av en legemiddelinformasjonstjeneste for gravide og ammende
(The University of Bergen, 2012-05-21)Introduksjon: Mange kvinner opplever ulike plager forbundet med graviditet, og enkelte har behov for legemidler. Gravide og ammende kan også ha kronisk sykdom, som krever legemiddelbehandling. En studie har vist at en høy ...Master thesis -
Farmasøytrekvirering av legemidler sett fra farmasøytens perspektiv
(The University of Bergen, 2011-05-20)Internasjonalt er farmasøytrekvirering et vidt begrep og praktiseres i forskjellige former. På bakgrunn av svineinfluensapandemien 2009/2010 besluttet HOD på kort varsel å innføre farmasøytrekvirering av de reseptpliktige ...Master thesis -
Formulering av kortisonpreparat til bruk ved binyrebarksvikt
(The University of Bergen, 2008-06-01)Master thesis -
Forsøk på Amplifisering, Kloning & Sekvensering av Humant Leukolektin
(The University of Bergen, 2011-08-15)Leukolektin er et nytt protein med hensyn til struktur og funksjon. Kartlegging er så vidt startet av mulige medisinske og biologiske effekter av proteinet. Kunnskapen om proteinet er i dag ganske begrenset fordi det ...Master thesis -
Fotokjemisk internalisering (PCI) av HER2-rettet immunotoksin; trastuzumab-saporin
(The University of Bergen, 2009-05-19)En begrensning for terapeutisk nytte av makromolekyler som utøver sin effekt intracellulært er at de etter opptak ved endocytose degraderes lysosomalt før de når sitt terapeutiske mål i cytosol. Fotokjemisk internalisering ...Master thesis -
Glucocorticoid pharmacogenetics in Addison's disease - The role of the immunophilin FK506-binding protein (FKBP51) for glucocorticoid sensitivity
(The University of Bergen, 2008-05-31)There is great variation in the inter-individual sensitivity to glucocorticoids. The immunophilin FK506 binding protein (FKBP51) confers short-loop negative feedback inhibition of the glucocorticoid signalling pathway. ...Master thesis -
Growing with dinosaurs: natural products from the Cretaceous relict Metasequoia glyptostroboides Hu & Cheng - a molecular reservoir from the ancient world with potential in modern medicine
(Springer, 2015-02-22)After the sensational rediscovery of living exemplars of the Cretaceous relict Metasequoia glyptostroboides—a tree previously known exclusively from fossils from various locations in the northern hemisphere, there has been ...Journal article -
Growth of glioblastoma xenografts in the brains of NOD/SCID mice following administration of a demyelinating agent
(The University of Bergen, 2011-06-16)Background: Glioblastoma multiforme (GBM) is an incurable and fatal brain cancer with short median survival. Due to the infiltrative growth into the surrounding brain parenchyma, radical surgery is not possible and their ...Master thesis -
Helsepersonells erfaringar, tankar og haldningar til behovsmedisinering i sjukeheimar
(The University of Bergen, 2009-05-20)Behovslegemiddel er meint å bli gitt som respons på eit symptom eller medisinsk behov som oppstår hjå pasienten. Behovslegemiddel blir anten ført opp på den enkelte pasient sitt legemiddelkort, eller så kan ein nytte seg ...Master thesis -
Herbal plants used in traditional Chinese medicine as a source of compounds with potential medical utilities - identification, characterization and organization
(The University of Bergen, 2010-05-19)The history and knowledge of Chinese herbal medicine is over 3000 years old, and over 10 000 herbs are recorded and are in use for different conditions. This is an enormous amount of knowledge that can be used to find new ...Master thesis -
Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly
(BioMed Central, 2011-02-16)Background: The HIV-1 p6 Gag protein regulates the final abscission step of nascent virions from the cell membrane by the action of two late assembly (L-) domains. Although p6 is located within one of the most polymorphic ...Peer reviewedJournal article -
The Host-Pathogen interaction of Human Cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domains
(BioMed Central, 2011-12-20)Background: Cyclophilin A (CypA) represents a potential key molecule in future antiretroviral therapy since inhibition of CypA suppresses human immunodeficiency virus type 1 (HIV-1) replication. CypA interacts with the ...Journal article -
Hvilke ønsker og behov har pasienter med revmatisme i forbindelse med legemiddelopplæringen?
(The University of Bergen, 2009-05-20)Legemidler utgjør et viktig behandlingsalternativ ved de fleste revmatiske lidelser. Disse er imidlertid forbundet med høy risiko for alvorlige bivirkninger og tap av effekt etter en tids bruk. Dette gjør legemiddelbehandlingen ...Master thesis -
Identification of inhibitors of tryptophan hydroxylase 1
(The University of Bergen, 2014-05-20)Background: In this study we use molecular docking to find compounds that interact with the enzyme tryptophan hydroxylase (TPH), followed by experimental validation. TPH is a tetrahydrobiopterin (BH4) dependent enzyme that ...Master thesis -
Identification of pharmacological chaperones for Phenylalanine Hydroxylase. A virtual screening approach to discover novel drug candidates for treatment of phenylketonuria
(The University of Bergen, 2014-05-20)Phenylalanine hydroxylase (PAH) is an enzyme that catalyses the hydroxylation of phenylalanine into tyrosine in the liver, which is the rate-limiting step in phenylalanine catabolism. PAH is a non-heme iron-dependent ...Master thesis -
Identification of the functional role of GSK3β in the ex vivo female rat heart at ischemic reperfusion--with special reference to Akt-dependent signalling
(The University of Bergen, 2009-05-14)Coronary heart disease is the leading cause of death worldwide, arising mainly from ischemic heart disease. Currently, the most effective method for reducing mortality in patients suffering from a coronary occlusion is ...Master thesis -
Identifikasjon av fettsyrer i omega-3 produkter ved hjelp av gasskromatografi med massespektrometrisk deteksjon
(The University of Bergen, 2012-08-24)The purpose of this study was to identify fatty acids in omega-3 products that are sold in the market in different countries and build databases of mass spectra and chromatographic retention indices. These databases can ...Master thesis
