Browsing Centre for Pharmacy by Author "Schubert, Ulrich"
Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly Votteler, Jörg; Neumann, Liane; Hahn, Sabine; Hahn, Friedrich; Rauch, Pia; Schmidt, Kerstin; Studtrucker, Nicole; Solbak, Sara Marie Øie; Fossen, Torgils; Henklein, Peter; Ott, David E.; Holland, Gudrun; Bannert, Norbert; Schubert, Ulrich (BioMed Central, 2011-02-16)Background: The HIV-1 p6 Gag protein regulates the final abscission step of nascent virions from the cell membrane by the action of two late assembly (L-) domains. Although p6 is located within one of the most polymorphic ...Peer reviewedJournal article
The Host-Pathogen interaction of Human Cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domains Solbak, Sara Marie Øie; Wray, Victor; Horvli, Ole; Raae, Arnt Johan; Flydal, Marte Innselset; Henklein, Petra; Henklein, Peter; Nimtz, Manfred; Schubert, Ulrich; Fossen, Torgils (BioMed Central, 2011-12-20)Background: Cyclophilin A (CypA) represents a potential key molecule in future antiretroviral therapy since inhibition of CypA suppresses human immunodeficiency virus type 1 (HIV-1) replication. CypA interacts with the ...Journal article