Now showing items 1-2 of 2
Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly
(BioMed Central, 2011-02-16)
Background: The HIV-1 p6 Gag protein regulates the final abscission step of nascent virions from the cell membrane by the action of two late assembly (L-) domains. Although p6 is located within one of the most polymorphic ...
The Host-Pathogen interaction of Human Cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domains
(BioMed Central, 2011-12-20)
Background: Cyclophilin A (CypA) represents a potential key molecule in future antiretroviral therapy since inhibition of CypA suppresses human immunodeficiency virus type 1 (HIV-1) replication. CypA interacts with the ...