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Recent Submissions

  • A restrictive policy for red blood cell transfusion in older hip fracture patients: experiences from a patient register 

    Martinsen, Mette; Valland, Haldor; Solheim, Ludvig Fjeld; Holvik, Kristin; Ranhoff, Anette Hylen (BioMed Central, 2016-02-09)
    Background: Allogeneic red blood cell transfusions (ABT) are common in older hip fracture patients. Recent research supports a restrictive transfusion policy. The aim was to study variation in hemoglobin (Hb) concentration, ...
    Journal article
  • Complications and discomfort of bronchoscopy: a systematic review 

    Leiten, Elise Orvedal; Martinsen, Einar Marius Hjellestad; Eagan, Tomas Mikal; Bakke, Per S.; Grønseth, Rune (Co-Action Publishing, 2016)
    Objective: To identify bronchoscopy-related complications and discomfort, meaningful complication rates, and predictors. Method: We conducted a systematic literature search in PubMed on 8 February 2016, using a search ...
    Journal article
  • Sexual activity and functioning in women treated for gynaecological cancers 

    Sekse, Ragnhild Johanne Tveit; Hufthammer, Karl Ove; Vika, Margrethe Elin (Wiley, 2017-02)
    Aims and objectives. A description and comparison of sexual activity and function in relation to various gynaecological cancer diagnoses, treatment modalities, age groups, psychological distress and health-related quality ...
    Journal article
  • A longitudinal follow-up of autoimmune polyendocrine syndrome type 1 

    Bruserud, Øyvind; Oftedal, Bergithe Eikeland; Landegren, Nils; Erichsen, Martina Moter; Bratland, Eirik; Lima, Kari; Jørgensen, Anders Palmstrøm; Myhre, Anne Grethe; Svartberg, Johan; Fougner, Kristian J; Bakke, Åsne; Nedrebø, Bjørn Gunnar; Mella, Bjarne; Breivik, Lars Ertesvåg; Viken, Marte K; Knappskog, Per; Cuida Marthinussen, Ileana Mihaela; Løvås, Kristian; Kämpe, Olle; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre (Oxford University Press, 2016-08)
    Context: Autoimmune polyendocrine syndrome type 1 (APS1) is a childhood-onset monogenic disease defined by the presence of two of the three major components: hypoparathyroidism, primary adrenocortical insufficiency, and ...
    Journal article
  • Prognostic significance of S100A4 expression in stage II and III colorectal cancer: results from a population-based series and a randomized phase III study on adjuvant chemotherapy 

    Pedersen, Kjetil Boye; Jacob, Havjin; Frikstad, Kari-Anne; Nesland, Jahn M; Mælandsmo, Gunhild; Dahl, Olav; Nesbakken, Arild; Flatmark, Kjersti (Wiley, 2016-08)
    Current clinical algorithms are unable to precisely predict which colorectal cancer patients would benefit from adjuvant chemotherapy, and there is a need for novel biomarkers to improve the selection of patients. The ...
    Journal article
  • Pulmonary changes in Norwegian fatal cases of pandemic influenza H1N1 (2009) infection: a morphologic and molecular genetic study 

    Voltersvik, Pål; Aqrawi, Lara Adnan; Dudman, Susanne Gjeruldsen; Hungnes, Olav; Bostad, Leif; Brokstad, Karl Albert; Cox, Rebecca Jane (Wiley, 2016-11)
    Background: During the pandemic outbreak of the 2009 swine influenza (A(H1N1) pdm09), 32 fatal cases occurred in Norway and 19 of these were included in this study. Objectives: We characterised pulmonary changes in these ...
    Journal article
  • Epidemiology and health related quality of life in hypoparathyroidism in Norway 

    Astor, Marianne; Løvås, Kristian; Debowska, Aleksandra; Eriksen, Erik Fink; Evang, Johan Arild; Fossum, Jan Christian; Fougner, Kristian J; Holte, Synnøve E.; Lima, Kari; Moe, Ragnar Bekkhus; Myhre, Anne Grethe; Kemp, E. Helen; Nedrebø, Bjørn Gunnar; Svartberg, Johan; Husebye, Eystein Sverre (Endocrine Society, 2016-08)
    Objective: The epidemiology of hypoparathyroidism (HP) is largely unknown. We aimed to determine prevalence, etiologies, health related quality of life (HRQOL) and treatment pattern of HP. Methods: Patients with HP and ...
    Journal article
  • Impaired lymphatic function accelerates cancer growth 

    Steinskog, Eli Sihn Samdal; Sagstad, Solfrid Johanne; Wagner, Marek; Karlsen, Tine Veronica; Yang, Ning; Markhus, Carl Erik Nordvik; Yndestad, Synnøve; Wiig, Helge; Eikesdal, Hans Petter (Impact Journals, 2016-06-13)
    Increased lymphangiogenesis is a common feature of cancer development and progression, yet the influence of impaired lymphangiogenesis on tumor growth is elusive. C3HBA breast cancer and KHT-1 sarcoma cell lines were ...
    Journal article
  • DNA Methylation Score as a Biomarker in Newborns for Sustained Maternal Smoking during Pregnancy 

    Reese, Sarah E; Zhao, Shanshan; Wu, Michael C; Joubert, Bonnie R; Parr, Christine Louise; Håberg, Siri Eldevik; Ueland, Per Magne; Nilsen, Roy Miodini; Midttun, Øivind; Vollset, Stein Emil; Peddada, Shyamal D; Nystad, Wenche; London, Stephanie J (National Institute of Environmental Health Sciences, 2017-04)
    Background: Maternal smoking during pregnancy, especially when sustained, leads to numerous adverse health outcomes in offspring. Pregnant women disproportionately underreport smoking and smokers tend to have lower follow-up ...
    Journal article
  • Incidence of utilization- and symptom-defined COPD exacerbations in hospital- and population-recruited patients 

    Erdal, Marta; Johannessen, Ane; Eagan, Tomas Mikal; Bakke, Per S.; Gulsvik, Amund; Grønseth, Rune (Dovepress, 2016-09)
    Objectives: The objectives of this study were to estimate the impact of recruitment source and outcome definition on the incidence of acute exacerbations of COPD (AECOPD) and explore possible predictors of AECOPD. Patients ...
    Journal article
  • Impact of KRAS, BRAF, PIK3CA, TP53 status and intraindividual mutation heterogeneity on outcome after liver resection for colorectal cancer metastases 

    Løes, Inger Marie; Immervoll, Heike; Sorbye, Halfdan; Angelsen, Jon-Helge; Horn, Arild; Knappskog, Stian; Lønning, Per Eystein (Wiley, 2016-04)
    We determined prognostic impact of KRAS, BRAF, PIK3CA and TP53 mutation status and mutation heterogeneity among 164 colorectal cancer (CRC) patients undergoing liver resections for metastatic disease. Mutation status was ...
    Journal article
  • Implementation of Medical Abortion in Norway 1998-2013 

    Løkeland, Mette (The University of Bergen, 2015-04-17)
    Background. Medical abortion is a secure way of terminating a pregnancy. Since 1998, medical abortion with mifepristone and misoprostol has been available in Norway. During the last 16 years, the accessibility and use ...
    Doctoral thesis
  • MTHFD1 and relevant biomarkers in cardiovascular disease: Observational studies in patients with suspected stable angina pectoris in Norway 

    Ding, Yunpeng (The University of Bergen, 2017-03-24)
    Background: As the leading cause of death globally, cardiovascular disease (CVD) is a major public health burden. Epidemiological and experimental studies consistently demonstrate an association between elevated total ...
    Doctoral thesis
  • Headache in systemic lupus erythematosus and primary Sjogren's syndrome 

    Tjensvoll, Anne Bolette (The University of Bergen, 2016-11-09)
    Background Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease which can affect multiple organs. The central nervous system (CNS) is frequently affected, and headache, especially migraine, ...
    Doctoral thesis
  • Flow cytometry based analyses as a tool in biomarker discovery for patient stratification in primary Sjögren’s syndrome 

    Davies, Richard Allan (The University of Bergen, 2017-03-09)
    Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease characterized by lymphocytic infiltrates of exocrine glands, notably the salivary and lacrimal glands combined with immune-mediated glandular destruction. ...
    Doctoral thesis
  • An optimized multiplex flow cytometry protocol for the analysis of intracellular signaling in peripheral blood mononuclear cells 

    Davies, Richard Allan; Vogelsang, Petra; Jonsson, Roland; Appel, Silke (Elsevier, 2016-09)
    Phosphoflow cytometry is increasingly being used as a tool for the discovery of biomarkers used in the treatment and monitoring of disease and therapy. The ability to measure numerous phospho-protein targets simultaneously ...
    Journal article
  • Giardia-specific cellular immune responses in post-giardiasis chronic fatigue syndrome 

    Hanevik, Kurt; Kristoffersen, Einar; Mørch, Kristine; Rye, Kristin Paulsen; Sørnes, Steinar; Svärd, Staffan; Bruserud, Øystein; Langeland, Nina (BioMed Central, 2017-01-28)
    Background: The role of pathogen specific cellular immune responses against the eliciting pathogen in development of post-infectious chronic fatigue syndrome (PI-CFS) is not known and such studies are difficult to perform. ...
    Journal article
  • Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth 

    Holst, Frederik; Høivik, Erling Andre; Gibson, William J.; Taylor-Weiner, Amaro; Schumacher, Steven E.; Asmann, Yan W.; Grossmann, Patrick; Trovik, Jone; Necela, Brian M.; Thompson, E. Aubrey; Meyerson, Matthew; Beroukhim, Rameen; Salvesen, Helga; Cherniack, Andrew D. (Nature Publishing Group, 2016-05-10)
    The estrogen receptor alpha (ERα) is highly expressed in both endometrial and breast cancers, and represents the most prevalent therapeutic target in breast cancer. However, anti-estrogen therapy has not been shown to be ...
    Journal article
  • Modeling psychiatric disorders: From genomic findings to cellular phenotypes 

    Falk, Anna; Heine, Vivi M.; Harwood, Adrian J.; Sullivan, Patrick F.; Peitz, Michael; Brüstle, Oliver; Shen, Sanbring; Sun, Yuh-Man; Glover, Joel; Posthuma, Daniëlle; Djurovic, Srdjan (Nature Publishing Group, 2016)
    Major programs in psychiatric genetics have identified >150 risk loci for psychiatric disorders. These loci converge on a small number of functional pathways, which span conventional diagnostic criteria, suggesting a partly ...
    Journal article
  • Females report higher postoperative pain scores than males after ankle surgery 

    Storesund, Anette; Krukhaug, Yngvar; Olsen, Marit Vassbotten; Rygh, Lars Jørgen; Nilsen, Roy Miodini; Norekvål, Tone M. (Elsevier, 2016-07)
    Objectives: The majority of patients experience moderate-to-intense pain following ankle surgery. Early, adequate treatment of postoperative pain is desirable for optimal pain relief, which in turn may facilitate optimal ...
    Journal article

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