Blar i Department of Clinical Science på tittel
Viser treff 1013-1032 av 2325
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How many days of continuous physical activity monitoring reliably represent time in different intensities in cancer survivors
(Journal article; Peer reviewed, 2023)Background Physical activity (PA) monitoring is applied in a growing number of studies within cancer research. However, no consensus exists on how many days PA should be monitored to obtain reliable estimates in the cancer ... -
How participatory is parental consent in low literacy rural settings in low income countries? Lessons learned from a community based study of infants in South India
(Peer reviewed; Journal article, 2011-02-15)Background A requisite for ethical human subjects research is that participation should be informed and voluntary. Participation during the informed consent process by way of asking questions is an indicator of the extent ... -
How, not if, is the question mycologists should be asking about DNA-based typification
(Journal article; Peer reviewed, 2023)Fungal metabarcoding of substrates such as soil, wood, and water is uncovering an unprecedented number of fungal species that do not seem to produce tangible morphological structures and that defy our best attempts at ... -
HSF1 Can Prevent Inflammation following Heat Shock by Inhibiting the Excessive Activation of the ATF3 and JUN&FOS Genes
(Journal article; Peer reviewed, 2022)Heat Shock Factor 1 (HSF1), a transcription factor frequently overexpressed in cancer, is activated by proteotoxic agents and participates in the regulation of cellular stress response. To investigate how HSF1 level affects ... -
Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins
(Peer reviewed; Journal article, 2014)Differences in general cognitive ability (intelligence) account for approximately half of the variation in any large battery of cognitive tests and are predictive of important life events including health. Genome-wide ... -
Human Embryonic Development : Effects of Physical Activity and Sleep in Physiological Pregnancies
(Doctoral thesis, 2024-05-03)Bakgrunn: Forskningsfeltet "Developmental Origin of Health and Disease" (DOHaD) har vist hvor betydningsfull fosterutviklingen er for individets fremtidige helse og sykdomsrisiko. I senere år har den tidligste perioden av ... -
Human gain-of-function variants in HNF1A confer protection from diabetes but independently increase hepatic secretion of atherogenic lipoproteins
(Journal article; Peer reviewed, 2023)Loss-of-function mutations in hepatocyte nuclear factor 1A (HNF1A) are known to cause rare forms of diabetes and alter hepatic physiology through unclear mechanisms. In the general population, 1:100 individuals carry a ... -
A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia
(Journal article; Peer reviewed, 2021)While neurodevelopmental abnormalities have been associated with schizophrenia (SCZ), the role of astroglia in disease pathophysiology remains poorly understood. In the present study, we used a human induced pluripotent ... -
Human Leukocyte Antigen alleles associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
(Journal article; Peer reviewed, 2020)The etiology and pathogenesis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) are unknown, and autoimmunity is one of many proposed underlying mechanisms. Human Leukocyte Antigen (HLA) associations are ... -
Human mucosal IgA immune responses against enterotoxigenic escherichia coli
(Journal article; Peer reviewed, 2020-08-29)Infection with enterotoxigenic Escherichia coli (ETEC) is a major contributor to diarrheal illness in children in low- and middle-income countries and travelers to these areas. There is an ongoing effort to develop vaccines ... -
Humanized Ovarian Cancer Patient-Derived Xenografts for Improved Preclinical Evaluation of Immunotherapies
(Journal article; Peer reviewed, 2022)High-grade serous ovarian cancer (HGSOC) has poor prognosis and new treatment modalities are needed. Immunotherapy, with checkpoint inhibitors, have demonstrated limited impact. To evaluate the suitability for immunotherapeutics, ... -
Humoral and cellular immune responses after pandemic and seasonal influenza vaccination in humans
(Doctoral thesis, 2022-06-22)Vaccination is the most effective prophylaxis against epidemic and pandemic influenza. Annual seasonal influenza vaccination is recommended for high-risk groups such as younger children <5 years old and occupational workers ... -
Hva består oksymetriparametrene på blodgassutskriften av?
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Hva betyr tidligere hjerte- og karsykdom eller kreft for risiko for død etter påvist SARS-CoV-2?
(Journal article; Peer reviewed, 2020)BAKGRUNN Hjerte- og karsykdommer og kreft har vært beskrevet som mulige risikofaktorer for død av covid-19. Hensikten med studien er å undersøke om tidligere påvist hjerte- og karsykdom eller kreft har påvirket risiko for ... -
Hvilke ønsker og behov har pasienter med revmatisme i forbindelse med legemiddelopplæringen?
(Master thesis, 2009-05-20)Legemidler utgjør et viktig behandlingsalternativ ved de fleste revmatiske lidelser. Disse er imidlertid forbundet med høy risiko for alvorlige bivirkninger og tap av effekt etter en tids bruk. Dette gjør legemiddelbehandlingen ... -
Hvordan har endringer i omgivelsene i apotek forandret farmasøytens yrkesrolle?
(Master thesis, 2022-05-20)Inntil for omtrent tretti år siden var apotekene et «lukket» system som hadde som mål å sørge for legemiddelforsyning til befolkningen. Kunden måtte levere resept fra seg i reseptmottaket og komme tilbake seinere for ... -
Hydroxyurea synergizes with valproic acid in wild-type p53 acute myeloid leukaemia
(Peer reviewed; Journal article, 2016)Palliative care in acute myeloid leukaemia (AML) is inadequate. For elderly patients, unfit for intensive chemotherapy, median survival is 2–3 months. As such, there is urgent demand for low-toxic palliative alternatives. ... -
Hyperferritinemia—a clinical overview
(Journal article; Peer reviewed, 2021)Ferritin is one of the most frequently requested laboratory tests in primary and secondary care, and levels often deviate from reference ranges. Serving as an indirect marker for total body iron stores, low ferritin is ... -
Hyperglycemia in pregnancy. : Diagnostics, biomarkers, follow-up, and monitoring of glycemic control
(Doctoral thesis, 2023-02-24)Diabetes mellitus er blant de største globale folkehelseutfordringene i vår tid. Hyperglykemi affiserer ett av seks svangerskap og svangerskapsdiabetes (SVD) er den vanligste årsak. Gravide med hyperglykemi har økt risiko ... -
Hypertension in women: Should there be a sex-specific threshold?
(Journal article; Peer reviewed, 2021)Conventionally, hypertension is defined by the same blood pressure (BP) threshold (systolic BP ≥140 and/or diastolic BP ≥90 mmHg) in both women and men. Several studies have documented that women with hypertension are more ...