Browsing Department of Clinical Science by Subject "Chronic obstructive pulmonary disease"
Now showing items 1-3 of 3
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Airway obstruction, dynamic hyperinflation, and breathing pattern during incremental exercise in COPD patients
(Peer reviewed; Journal article, 2014-02-01)Ventilatory capacity is reduced in chronic obstructive pulmonary disease (COPD) patients. Tidal volume (VT) is lower and breathing frequency higher at a given ventilation (VE) compared to healthy subjects. We examined ... -
A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry
(Peer reviewed; Journal article, 2015-12-03)Background Pulmonary function decline is a major contributor to morbidity and mortality among smokers. Post bronchodilator FEV1 and FEV1/FVC ratio are considered the standard assessment of airflow obstruction. We performed ... -
Nitric oxide synthase polymorphisms, gene expression and lung function in chronic obstructive pulmonary disease
(Peer reviewed; Journal article, 2013-11-06)Background: Due to the pleiotropic effects of nitric oxide (NO) within the lungs, it is likely that NO is a significant factor in the pathogenesis of chronic obstructive pulmonary disease (COPD). The aim of this study was ...