Blar i Department of Clinical Science på emneord "Genome-wide association study"
Viser treff 1-3 av 3
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Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease
(Peer reviewed; Journal article, 2014-09-21)Background: Chronic bronchitis (CB) is one of the classic phenotypes of COPD. The aims of our study were to investigate genetic variants associated with COPD subjects with CB relative to smokers with normal spirometry, and ... -
A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry
(Peer reviewed; Journal article, 2015-12-03)Background Pulmonary function decline is a major contributor to morbidity and mortality among smokers. Post bronchodilator FEV1 and FEV1/FVC ratio are considered the standard assessment of airflow obstruction. We performed ... -
MicroRNAs enrichment in GWAS of complex human phenotypes
(Peer reviewed; Journal article, 2015-04-16)Background: The genotype information carried by Genome-wide association studies (GWAS) seems to have the potential to explain more of the ‘missing heritability’ of complex human phenotypes, given improved statistical ...