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Diazoxide protects against doxorubicin-induced cardiotoxicity in the rat 

Hole, Lisa Drange; Larsen, Terje H.; Fossan, Kjell Ove; Limé, Fredrik; Schjøtt, Jan (BioMed Central, 2014-05-27)
Aim: Chemotherapy with doxorubicin is limited by cardiotoxicity. Free radical generation and mitochondrial dysfunction are thought to contribute to doxorubicin-induced cardiac failure. In this study we wanted to investigate ...

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Type
Journal article (1)
Date Issued
2014 (1)
AuthorFossan, Kjell Ove (1)Hole, Lisa Drange (1)Larsen, Terje H. (1)Limé, Fredrik (1)
Schjøtt, Jan (1)
Subject
5-hydroxydecanoate (1)
Cardiotoxicity (1)Diazoxide (1)Doxorubicin (1)Doxorubicinol (1)
Ex vivo (1)
Heart (1)
Hydrogenperoxide (1)
Rat (1)
Troponin T (1)
JournalBMC Pharmacology and Toxicology (1)

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