Now showing items 1-3 of 3
HER2 expression patterns in paired primary and metastatic endometrial cancer lesions
(Nature Publishing Group, 2017-11-23)
Background: Despite successful implementation of drugs targeting the human epidermal growth factor receptor 2 (HER2) receptor in breast and gastric cancers, the potential of HER2 as a therapeutic target in other cancers ...
Aneuploidy related transcriptional changes in endometrial cancer link low expression of chromosome 15q genes to poor survival
(Impact Journals, 2017)
Aneuploidy is a widely studied prognostic marker in endometrial cancer (EC), however, not implemented in clinical decision-making. It lacks validation in large prospective patient cohorts adjusted for currently standard ...
ATAD2 overexpression links to enrichment of B-MYBtranslational signatures and development of aggressive endometrial carcinoma
(Impact Journals, 2015)
We have explored the potential for clinical implementation of ATAD2 as a biomarker for aggressive endometrial cancer by investigating to what extent immunohistochemical (IHC) staining for ATAD2 is feasible, reflects clinical ...