Recent Submissions

  • Intake of baked cod fillet resulted in lower serum cholesterol and higher long chain n-3 PUFA concentrations in serum and tissues in hypercholesterolemic obese Zucker fa/fa rats 

    Vikøren, Linn Anja Slåke; Drotningsvik, Aslaug; Bergseth, Marthe Tønder; Mjøs, Svein Are; Austgulen, Maren Hoff; Mellgren, Gunnar; Gudbrandsen, Oddrun Anita (MDPI, 2018-06-28)
    Increasing evidence indicates that lean fish consumption may benefit cardiovascular health. High cholesterol and low n-3 PUFA concentrations in serum are associated with an increased risk of coronary heart disease; therefore, ...
    Journal article
  • Gender-related differences in cardiometabolic risk factors and lifestyle behaviors in treatment-seeking adolescents with severe obesity 

    Barstad, Lisa Ha; Juliusson, Petur Benedikt; Johnson, Line Kristin; Hertel, Jens Kristoffer; Lekhal, Samira; Hjelmesæth, Jøran (BMC, 2018-02-14)
    Background: Obesity during adolescence is associated with cardiovascular mortality in adulthood. The adverse obesity-related cardiometabolic risk profile is already observed in adolescence. We aimed to examine possible ...
    Journal article
  • Impact of HIV and type 2 diabetes on gut microbiota diversity, tryptophan catabolism and endothelial dysfunction 

    Hoel, Hedda Benedicte; Hove-Skovsgaard, Malene; Hov, Johannes Espolin Roksund; Gaardbo, Julie Christine; Holm, Kristian; Kummen, Martin; Rudi, Knut; Nwosu, Felix; Valeur, Jørgen; Gelpi, Marco; Seljeflot, Ingebjørg; Ueland, Per Magne; Gerstoft, Jan; Ullum, Henrik; Aukrust, Pål; Nielsen, Susanne Dam; Trøseid, Marius (Springer Nature, 2018-04-30)
    HIV infection and type 2 diabetes are associated with altered gut microbiota, chronic inflammation, and increased cardiovascular risk. We aimed to investigate the combined effect of these diseases on gut microbiota composition ...
    Journal article
  • Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia 

    Witt, Stephanie H.; Streit, F; Jungkunz, M; Frank, J; Awasthi, S; Reinbold, CS; Treutlein, J; Degenhardt, F; Forstner, AJ; Heilmann-Heimbach, S; Dietl, L; Schwarze, CE; Schendel, D; Strohmaier, Jana; Abdellaoui, A; Adolfsson, Rolf; Air, TM; Akil, Huda; Alda, Martin; Alliey-Rodriguez, N; Andreassen, Ole Andreas; Babadjanova, Gulia; Bass, N; Bauer, M; Baune, Bernhard T.; Bellivier, Frank; Bergen, Sarah E; Bethell, A; Biernacka, Joanna M.; Blackwood, Douglas H.R.; Boks, Marco P; Boomsma, Dorret I.; Borglum, Anders D; Borrmann-Hassenbach, M; Brennan, P; Budde, M; Buttenschon, HN; Byrne, Enda M.; Cervantes, P; Clarke, TK; Craddock, N; Cruceanu, C; Curtis, David; Czerski, Piotr M.; Dannlowski, Udo; Davis, T; de Geus, Eco J C; Di Florio, A; Djurovic, Srdjan; Domenici, Enrico; Edenberg, Howard J; Etain, Bruno; Fischer, SB; Forty, L; Fraser, C; Frye, M; Fullerton, JM; Gershon, Elliot S.; Gieglin, I; Gordon, Scott D; Gordon-Smith, K; Grabe, Hans Jörgen; Green, EK; Greenwood, TA; Grigoroiu-Serbanescu, Maria; Guzman-Parra, J; Hall, L; Hamshere, Marian; Hauser, J; Hautzinger, Martin; Heilbronner, U; Herms, Stefan; Hitturlingappa, S; HOFFMANN, PAVEL; Holmans, P; Hottenga, Jouke Jan; Jamain, Stephane; Jones, I; Jones, L; Juréus, Anna; Kahn, René S; Kammerer-Ciernioch, Jutta; Kirov, George; Kittel-Schneider, Sarah; Kloiber, Stefan; Knott, SV; Kogevinas, Manolis; Landen, M; Leber, M; Leboyer, Marion; Li, Qingqin S.; Lissowska, Jolanta; Lucae, Susanne; Martin, NG; Mayoral-Cleries, F; McElroy, SL; McIntosh, Andrew M; McKay, James D; McQuilling, A; Medland, Sarah E; Middeldorp, Christel M.; Milaneschi, Y; Mitchell, Philip B; Montgomery, Grant W; Mors, O; Mühleisen, Thomas W.; Muller-Myshok, B; Myers, Richard M; Nievergelt, Caroline M.; Nurnberger, John I.; O'Donovan, Michael C; Loohuis, Loes M. Olde; Ophoff, R; Oruc, Liliana; Owen, Michael J; Paciga, SA; Penninx, Brenda W J H; Perry, A; Pfennig, Andrea; Potash, James B.; Preisig, Martin; Reif, A; Rivas, F; Rouleau, GA; Schofield, Peter R; Schulze, Thomas G; Schwarz, M; Scott, L; Sinnamon, GCB; Stahl, Eli A.; Strauss, J; Turecki, G; Van der Auwera, S; Vedder, Helmut; Vincent, John B; Willemsen, Gonneke; Witt, CC; Wray, Naomi R; Xi, HS; Tadic, A; Dahmen, Norbert; Schott, Björn H; Cichon, Sven; Nothen, Markus M; Ripke, Stephan; Mobascher, A; Rujescu, Dan; Lieb, K; Roepke, S; Schmal, Christine; Bohus, Martin; Rietschel, Marcella; Morken, Gunnar; Gade, K (Springer Nature, 2017-06-20)
    Borderline personality disorder (BOR) is determined by environmental and genetic factors, and characterized by affective instability and impulsivity, diagnostic symptoms also observed in manic phases of bipolar disorder ...
    Journal article
  • Parental involvement in decision-making about their child's health care at the hospital 

    Aarthun, Antje; Øymar, Knut; Akerjordet, Kristin (Wiley Open Access, 2018-07-30)
    Aim: To explore parents’ experiences on parental involvement in decision‐making about their child’s health care at the hospital and to identify how health professionals can improve parental involvement. Design: An ...
    Journal article
  • The association between alcohol consumption and risk of hip fracture differs by age and gender in Cohort of Norway: a NOREPOS study 

    Søgaard, Anne-Johanne; Ranhoff, Anette Hylen; Meyer, Haakon E; Omsland, Tone Kristin; Nystad, Wenche; Tell, Grethe S.; Holvik, Kristin (Springer, 2018-11)
    Summary: The association between alcohol consumption and hip fracture differed by gender: Men aged 30–59 years drinking frequently or 14+ gl/week had higher risk than moderate drinkers. No significant association was ...
    Journal article
  • Polarizing versus depolarizing blood cardioplegia: An experimental study of myocardial function, metabolism and ultrastructure following cardiopulmonary bypass and cardioplegic arrest 

    Aass, Terje (The University of Bergen, 2019-01-11)
    In cardiothoracic surgery, the use of the heart-lung machine for cardiopulmonary bypass (CPB) and induced cardiac arrest, cardioplegia, is required for performing the majority of the surgical procedures. Myocardial ...
    Doctoral thesis
  • Role of rare HNF1A variants function in monogenic and type 2 diabetes 

    Najmi, Laeya Abdoli (The University of Bergen, 2018-10-26)
    Variants in the transcription factor gene HNF1A have been identified in subjects with maturity-onset diabetes of the young (MODY) type 3, type 2 diabetes, as well as in children with apparent type 1 diabetes. One of the ...
    Doctoral thesis
  • Association of a Low-Frequency Variant in HNF1A With Type 2 Diabetes in a Latino Population 

    Estrada, Karol; Aukrust, Ingvild; Bjørkhaug, Lise; Najmi, Laeya Abdoli; Njølstad, Pål Rasmus; MacArthur, Daniel G.; The SIGMA Type 2 Diabetes Consortium (American Medical Association, 2014-06)
    Importance: Latino populations have one of the highest prevalences of type 2 diabetes worldwide. Objectives: To investigate the association between rare protein-coding genetic variants and prevalence of type 2 diabetes ...
    Journal article
  • Preclinical models and molecular biomarkers. Tools to improve treatment in endometrial carcinoma 

    Fonnes, Tina (The University of Bergen, 2018-11-30)
    Background: Endometrial carcinoma is the fourth most common cancer in European women, and incidence is increasing. No major improvements in treatment or survival have been achieved over the last decades, and an individualized ...
    Doctoral thesis
  • Multimodal Imaging of Orthotopic Mouse Model of Endometrial Carcinoma 

    Haldorsen, Ingfrid S.; Popa, Mihaela Lucia; Fonnes, Tina; Brekke, Njål; Kopperud, Reidun Kristin; Visser, Nicole C.; Rygh, Cecilie Brekke; Pavlin, Tina; Salvesen, Helga Birgitte; McCormack, Emmet; Krakstad, Camilla (Public Library of Science, 2015-08-07)
    Background: Orthotopic endometrial cancer models provide a unique tool for studies of tumour growth and metastatic spread. Novel preclinical imaging methods also have the potential to quantify functional tumour ...
    Journal article
  • Distinct T and NK cell populations may serve as immune correlates of protection against symptomatic pandemic influenza A(H1N1) virus infection during pregnancy 

    Savic, Miloje; Dembinski, Jennifer Lynn; Laake, Ida; Hungnes, Olav; Cox, Rebecca Jane; Oftung, Fredrik; Trogstad, Lill; Mjaaland, Siri (PLOS, 2017-11-16)
    Maternal influenza infection during pregnancy is associated with increased risk of morbidity and mortality. However, the link between the anti-influenza immune responses and health-related risks during infection is not ...
    Journal article
  • Left Vocal Cord Paralysis After Patent Ductus Arteriosus Ligation: A Systematic Review. 

    Engeseth, Merete Salveson; Olsen, Nina Rydland; Mæland, Silje; Halvorsen, Thomas; Goode, Adam; Røksund, Ola Drange (Elsevier, 2018)
    Context: Extremely premature (EP) infants are at increased risk of left vocal cord paralysis (LVCP) following surgery for patent ductus arteriosus (PDA). Objective: A Systematical Review was conducted to investigate the ...
    Journal article
  • Parents’ Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder—Data from a Norwegian Sample 

    Johannessen, Tor Jarle; Nærland, Terje; Hope, Sigrun; Torske, Tonje; Høyland, Anne Lise; Strohmaier, Jana; Heiberg, Arvid; Rietschel, Marcella; Djurovic, Srdjan; Andreassen, Ole Andreas (MDPI, 2017-05-18)
    Clinical genetic testing (CGT) of children with autism spectrum disorder (ASD) may have positive and negative effects. Knowledge about parents’ attitudes is needed to ensure good involvement of caregivers, which is crucial ...
    Journal article
  • Genetic variation in 117 myelination-related genes in schizophrenia: Replication of association to lipid biosynthesis genes 

    Stokowy, Tomasz; Polushina, Tatiana; Sønderby, Ida Elken; Karlsson, Robert; Giddaluru, Sudheer; Le Hellard, Stephanie; Bergen, Sarah E; Sullivan, Patrick F; Andreassen, Ole Andreas; Djurovic, Srdjan; Hultman, Christina M.; Steen, Vidar Martin (Nature Publishing Group, 2018-05-02)
    Schizophrenia is a serious psychotic disorder with high heritability. Several common genetic variants, rare copy number variants and ultra-rare gene-disrupting mutations have been linked to disease susceptibility, but there ...
    Journal article
  • Paternal and maternal obesity but not gestational weight gain is associated with type 1 diabetes 

    Magnus, Maria Christine; Olsen, Sjurdur Frodi; Granström, Charlotta; Lund-Blix, Nicolai Andre; Svensson, Jannet; Johannesen, Jesper; Fraser, Abigail; Skrivarhaug, Torild; Joner, Geir; Njølstad, Pål Rasmus; Størdal, Ketil; Stene, Lars Christian Mørch (Oxford University Press, 2018-04)
    Background Our objective was to examine the associations of parental body mass index (BMI) and maternal gestational weight gain with childhood-onset type 1 diabetes. Comparing the associations of maternal and paternal BMI ...
    Journal article
  • Primary aldosteronism in Western Norway. Studies of diagnostic approach and treatment outcome 

    Grytaas, Marianne Aardal (The University of Bergen, 2018-09-06)
    Primary aldosteronism (PA) is the most common cause of secondary hypertension (HT), accounting for 5 to 12% of all hypertensive individuals. Patients with PA experience increased cardiovascular, renal and metabolic ...
    Doctoral thesis
  • Cardiac magnetic resonance imaging of myocardial mass and fibrosis in primary aldosteronism 

    Grytaas, Marianne; Sellevåg, Kjersti; Thordarson, Hrafnkell B; Husebye, Eystein Sverre; Løvås, Kristian; Larsen, Terje H (Bioscientifica, 2018-03)
    Background: Primary aldosteronism (PA) is associated with increased cardiovascular morbidity, presumably due to left ventricular (LV) hypertrophy and fibrosis. However, the degree of fibrosis has not been extensively ...
    Journal article
  • Transcapillary fluid balance in children. Methodology and new clinical studies. To the interstitial space - and back again 

    Guthe, Hans Jørgen Timm (The University of Bergen, 2016-04-29)
    Objective: The capillaries represent a semipermeable barrier between the blood and the interstitium, where there is a continuous exchange of fluid and solutes. Numerous factors affect the tight regulation of this movement ...
    Doctoral thesis
  • Transcapillary fluid flux and inflammatory response during neonatal therapeutic hypothermia: an open, longitudinal, observational study 

    Guthe, Hans Jørgen Timm; Nedrebø, Torbjørn; Damås, Jan Kristian; Wiig, Helge; Berg, Ansgar (BioMed Central, 2018-02-23)
    Background: Therapeutic hypothermia is neuroprotective in asphyxiated neonates by counteracting mechanisms contributing to brain injury. Although an initial increased permeability is part of an inflammatory reaction ...
    Journal article

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