Now showing items 158-177 of 487

    • Fatigue in psoriasis: a phenomenon to be explored 

      Skoie, Inger Marie; Ternowitz, Thomas; Jonsson, Grete; Norheim, Katrine Brække; Omdal, Roald (Wiley, 2015-05)
      Fatigue is a prevalent and substantial phenomenon in many patients with chronic inflammatory diseases, often rated by patients as the most troublesome symptom and aspect of their disease. It frequently interferes with ...
      Journal article
    • Females report higher postoperative pain scores than males after ankle surgery 

      Storesund, Anette; Krukhaug, Yngvar; Olsen, Marit Vassbotten; Rygh, Lars Jørgen; Nilsen, Roy Miodini; Norekvål, Tone M. (Elsevier, 2016-07)
      Objectives: The majority of patients experience moderate-to-intense pain following ankle surgery. Early, adequate treatment of postoperative pain is desirable for optimal pain relief, which in turn may facilitate optimal ...
      Journal article
    • Fetal size in the second trimester is associated with the duration of pregnancy, small fetuses having longer pregnancies 

      Johnsen, Synnøve Lian; Wilsgaard, Tom; Rasmussen, Svein; Hanson, Mark A.; Godfrey, Keith M.; Kiserud, Torvid (BioMed Central, 2008-07-16)
      Background: Conventionally, the pregnancy duration is accepted to be 280–282 days. Fetuses determined by ultrasound biometry to be small in early pregnancy, have an increased risk of premature birth. We speculate that ...
      Journal article
    • First in-mouse development and application of a surgically relevant xenograft model of ovarian carcinoma 

      Helland, Øystein; Popa, Mihaela Lucia; Vintermyr, Olav Karsten; Molven, Anders; Gjertsen, Bjørn Tore; Bjørge, Line; McCormack, Emmet (The University of Bergen, 2014-03-04)
      Purpose: Preclinical models of epithelial ovarian cancer have not been exploited to evaluate the clinical standard combination therapy of surgical debulking with follow-up chemotherapy. As surgery is critical to patient ...
      Journal article
    • Fish oil and krill oil differentially modify the liver and brain lipidome when fed to mice 

      Skorve, Jon; Hilvo, Mika; Vihervaara, Terhi; Burri, Lena; Bohov, Pavol; Tillander, Veronika; Bjørndal, Bodil; Suoniemi, Matti; Laaksonen, Reijo; Ekroos, Kim; Berge, Rolf Kristian; Alexson, Stefan E.H. (BioMed Central, 2015-08-11)
      Background: Marine food is an important source of omega-3 fatty acids with beneficial health effects. Oils from marine organisms have different fatty acid composition and differ in their molecular composition. Fish oil ...
      Journal article
    • Fish oil and krill oil supplementations differentially regulate lipid catabolic and synthetic pathways in mice 

      Tillander, Veronika; Bjørndal, Bodil; Burri, Lena; Bohov, Pavol; Skorve, Jon; Berge, Rolf Kristian; Alexson, Stefan E. H. (BioMed Central, 2014-04-27)
      Background: Marine derived oils are rich in long-chain polyunsaturated omega-3 fatty acids, in particular eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which have long been associated with health promoting ...
      Journal article
    • A fish protein hydrolysate alters fatty acid composition in liver and adipose tissue and increases plasma carnitine levels in a mouse model of chronic inflammation 

      Bjørndal, Bodil; Berge, Christ; Ramsvik, Marie Sannes; Svardal, Asbjørn; Bohov, Pavol; Skorve, Jon; Berge, Rolf Kristian (BioMed Central, 2013-10-07)
      Background: There is growing evidence that fish protein hydrolysate (FPH) diets affect mitochondrial fatty acid metabolism in animals. The aim of the study was to determine if FPH could influence fatty acid metabolism ...
      Journal article
    • Flow cytometry based analyses as a tool in biomarker discovery for patient stratification in primary Sjögren’s syndrome 

      Davies, Richard Allan (The University of Bergen, 2017-03-09)
      Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease characterized by lymphocytic infiltrates of exocrine glands, notably the salivary and lacrimal glands combined with immune-mediated glandular destruction. ...
      Doctoral thesis
    • Folic acid supplementation and biomarkers of progression of sub-clinical coronary atherosclerosis in patients with stable angina pectoris. A WENBIT sub-study based on coronary angiography and intravascular ultrasound 

      Løland, Kjetil Halvorsen (The University of Bergen, 2014-04-09)
      Background: Coronary artery disease (CAD) is the leading cause of death in the world. Total plasma homocysteine (tHcy) is an independent risk factor for CAD, and while tHcy is lowered by folic acid (FA)/vitamin B12 (B12) ...
      Doctoral thesis
    • Forskningsveiledning - en av de essensielle faktorene på «veien til doktorgrad» 

      Lied, Gülen Arslan; Chen, Jian; Reikvam, Håkon (Universitetsforlaget, 2013)
      The journey to finish a PhD thesis is a long race, and several factors may play important roles in this process. A good working relationship between the supervisor and the candidate is an essential component for achieving ...
      Journal article
    • The frequencies of IFNγ+IL2+TNFα+ PPD-specific CD4+CD45RO+ T-cells correlate with the magnitude of the QuantiFERON® gold in-tube response in a prospective study of healthy Indian adolescents 

      Jenum, Synne; Grewal, Harleen; Hokey, David A.; Kenneth, John; Vaz, Mario; Doherty, Timothy Mark; Jahnsen, Frode Lars (PLoS, 2014-07-03)
      Background: QuantiFERON-TB Gold In-Tube (QFT) is an IFNγ-release assay used in the diagnosis of Mycobacterium tuberculosis (MTB) infection. The risk of TB progression increases with the magnitude of the MTB-specific ...
      Journal article
    • Frequency and prognostic implications of orthostatic hypotension and white matter hyperintensities in older people with mild dementia 

      Sønnesyn, Hogne (The University of Bergen, 2014-09-19)
      Background: In addition to cognitive impairments, dementia sufferers may have other problems as well, such as depression and orthostatic hypotension (OH), both of which according to previous studies may be associated ...
      Doctoral thesis
    • Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells 

      Ju, Young Seok; Tubio, José M.C.; Mifsud, William; Fu, Beiyuan; Davies, Helen R; Ramakrishna, Manasa; Li, Yilong; Yates, Lucy; Gundem, Gunes; Tarpey, Patrick S.; Behjati, Sam; Papaemmanuil, Elli; Martin, Sancha; Fullam, Anthony; Gerstung, Moritz; Nangalia, Jyoti; Green, Anthony R.; Caldas, Carlos; Borg, Åke; Tutt, Andrew; Michael Lee, Ming Ta; Van't Veer, Laura J.; Tan, Benita K.T.; Aparicio, Samuel; Span, Paul N.; Martens, John W.M.; Knappskog, Stian; Vincent-Salomon, Anne; Børresen-Dale, Anne-Lise; Eyfjörd, Jorunn Erla; Flanagan, Adrienne M.; Foster, Christopher; Neal, David E.; Cooper, Colin; Eeles, Rosalind; Lakhani, Sunil R.; Desmedt, Christine; Thomas, Gilles; Richardson, Andrea L.; Purdie, Colin A.; Thompson, Alastair M.; McDermott, Ultan; Yang, Fengtang; Nik-Zainal, Serena; Campbell, Peter J.; Stratton, Michael R. (Cold Spring Harbor Laboratory, 2015)
      Mitochondrial genomes are separated from the nuclear genome for most of the cell cycle by the nuclear double membrane, intervening cytoplasm, and the mitochondrial double membrane. Despite these physical barriers, we show ...
      Journal article
    • Friedreich ataxia in Norway - An epidemiological, molecular and clinical study Rare neurological diseases 

      Wedding, Iselin Marie; Kroken, Mette; Henriksen, Sandra Pilar; Selmer, Kaja Kristine; Fiskerstrand, Torunn; Knappskog, Per; Berge, Tone; Tallaksen, Chantal (BioMed Central, 2015-09-04)
      Background: Friedreich ataxia is an autosomal recessive hereditary spinocerebellar disorder, characterized by progressive limb and gait ataxia due to proprioceptive loss, often complicated by cardiomyopathy, diabetes and ...
      Journal article
    • Function and regulation of Steroid Receptor Coactivator 2. Transcriptional regulation of cellular metabolism 

      Madsen, Andre (The University of Bergen, 2015-12-18)
      Nuclear hormone receptors (NRs) associate with coregulators to enable complex programs of gene expression. The p160 steroid receptor coactivator 2 (SRC- 2/GRIP1) regulates metabolism and cellular processes in a tissue-specific ...
      Doctoral thesis
    • Functional studies of novel CYP21A2 mutations detected in Norwegian patients with congenital adrenal hyperplasia 

      Brønstad, Ingeborg; Breivik, Lars Ertesvåg; Methlie, Paal; Wolff, Anette Susanne Bøe; Bratland, Eirik; Nermoen, Ingrid; Løvås, Kristian; Husebye, Eystein Sverre (Bioscientifica, 2014)
      In about 95% of cases, congenital adrenal hyperplasia (CAH) is caused by mutations in CYP21A2 gene encoding steroid 21-hydroxylase (21OH). Recently, we have reported four novel CYP21A2 variants in the Norwegian population ...
      Journal article
    • Gel2DE - A software tool for correlation analysis of 2D gel electrophoresis data 

      Øye, Ola Kristoffer; Jørgensen, Katarina Mariann; Hjelle, Sigrun Margrethe; Sulen, André; Ulvang, Dag Magne; Gjertsen, Bjørn Tore (BioMed Central, 2013-07-06)
      Background: Two-dimensional gel electrophoresis (2DE) is a powerful technique for studying protein isoforms and their modifications. Existing commercial 2D image analysis tools rely on spot detection that limits analysis ...
      Journal article
    • Gender differences in childhood lyme neuroborreliosis 

      Tveitnes, Dag; Øymar, Knut (Hindawi publishing group, 2015-10-04)
      Background. Many neurological diseases show differences between genders. We studied gender differences in childhood Lyme neuroborreliosis (LNB) in an endemic area of Lyme borreliosis in Norway. Methods. In a population ...
      Journal article
    • Gender-related differences in cardiometabolic risk factors and lifestyle behaviors in treatment-seeking adolescents with severe obesity 

      Barstad, Lisa Ha; Juliusson, Petur Benedikt; Johnson, Line Kristin; Hertel, Jens Kristoffer; Lekhal, Samira; Hjelmesæth, Jøran (BMC, 2018-02-14)
      Background: Obesity during adolescence is associated with cardiovascular mortality in adulthood. The adverse obesity-related cardiometabolic risk profile is already observed in adolescence. We aimed to examine possible ...
      Journal article
    • Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949) 

      Davies, Gail; Armstrong, N; Bis, JC; Bressler, J; Chouraki, V; Giddaluru, Sudheer; Hofer, E; Ibrahim-Verbaas, CA; Kirin, M; Lahti, J; Van Der Lee, SJ; Le Hellard, Stephanie; Liu, T; Marioni, RE; Oldmeadow, C; Postmus, I; Smith, AV; Smith, JA; Thalamuthu, A; Thomson, R; Vitart, V; Wang, J; Yu, L; Zgaga, L; Zhao, W; Boxall, R; Harris, SE; Hill, WD; Liewald, DC; Luciano, M; Adams, H; Ames, D; Amin, N; Amouyel, P; Assareh, AA; Au, R; Becker, JT; Beiser, A; Berr, C; Bertram, L; Boerwinkle, E; Buckley, BM; Campbell, H; Corley, J; De Jager, PL; Dufouil, C; Eriksson, JG; Espeseth, Thomas; Faul, JD; Ford, I; Scotland, Generation; Gottesman, RF; Griswold, ME; Gudnason, V; Harris, TB; Heiss, G; Hofman, A; Holliday, EG; Huffman, J; Kardia, SLR; Kochan, N; Knopman, DS; Kwok, JB; Lambert, JC; Lee, T; Li, G; Li, SC; Loitfelder, M; Lopez, OL; Lundervold, Astri; Lundqvist, A; Mather, KA; Mirza, SS; Nyberg, L; Oostra, BA; Palotie, A; Papenberg, G; Pattie, A; Petrovic, K; Polasek, O; Psaty, BM; Redmond, P; Reppermund, S; Rotter, JI; Schmidt, H; Schuur, M; Schofield, PW; Scott, RJ; Steen, Vidar Martin; Stott, DJ; Van Swieten, JC; Taylor, KD; Trollor, J; Trompet, S; Uitterlinden, AG; Weinstein, G; Widen, E; Windham, BG; Jukema, JW; Wright, AF; Wright, MJ; Yang, Q; Amieva, H; Attia, JR; Bennett, DA; Brodaty, H; De Craen, AJM; Hayward, C; Ikram, MA; Lindenberger, U; Nilsson, LG; Porteous, DJ; Räikkönen, K; Rudan, I; Sachdev, PS; Schmidt, R; Schofield, PR; Srikanth, V; Starr, JM; Turner, ST; Weir, DR; Wilson, JF; Van Duijn, C; Launer, L; Fitzpatrick, AL; Seshadri, S; Mosley, TH; Deary, IJ; Reinvang, Ivar (Nature Publishing Group, 2015)
      General cognitive function is substantially heritable across the human life course from adolescence to old age. We investigated the genetic contribution to variation in this important, health- and well-being-related trait ...
      Journal article