Blar i Department of Clinical Science på tittel

Viser treff 179-198 av 2295

    • B vitamin and iron status during infancy 

      Torsvik, Ingrid Kristin (Doctoral thesis, 2015-01-30)
      Adequate nutrition during infancy is essential to ensure normal growth and development. Since 2001, World Health Organization (WHO) has recommended exclusive breast-feeding for the first 6 months of life, which puts great ...

    • B vitamin treatments modify the risk of myocardial infarction associated with a MTHFD1 polymorphism in patients with stable angina pectoris 

      Ding, Yunpeng; Pedersen, Eva Ringdal; Johansson, Stefan; Gregory III, Jesse F.; Ueland, Per Magne; Svingen, Gard Frodahl Tveitevåg; Helgeland, Øyvind; Meyer, Klaus; Fredriksen, Åse; Nygård, Ottar (Peer reviewed; Journal article, 2016-06)
      Background: Methylenetetrahydrofolate dehydrogenase (MTHFD1) catalyzes three sequential reactions that metabolize derivatives of tetrahydrofolate (THF) in folate-dependent one-carbon metabolism. Impaired MTHFD1 flux has ...

    • The B-lymphocyte chemokine CXCL13 in the cerebrospinal fluid of children with Lyme neuroborreliosis: associations with clinical and laboratory variables 

      Barstad, Bjørn; Tveitnes, Dag; Dalen, Ingvild; Noraas, Sølvi; Ask, Ingvild; Bosse, Franziskus Johannes; Øymar, Knut (Peer reviewed; Journal article, 2019)
      Background: The B-lymphocyte chemokine CXCL13 is increasingly considered as a useful early phase diagnostic marker of Lyme neuroborreliosis (LNB). However, the large variation in level of CXCL13 in the cerebrospinal fluid ...

    • B-vitamin Treatment Modifies the Mortality Risk Associated with Calcium Channel Blockers in Patients with Suspected Stable Angina Pectoris: A Prospective Cohort Study 

      Dhar, Indu; Svingen, Gard Frodahl Tveitevåg; Bjørnestad, Espen Øglænd; Ulvik, Arve; Saeed, Sahrai; Nygård, Ottar Kjell (Journal article; Peer reviewed, 2023)
      Background Calcium channel blockers (CCBs) are used for the treatment of cardiovascular disease (CVD), including angina pectoris, and hypertension; however, the effect on survival remains uncertain. CCBs impair fibrinolysis ...

    • Bacteraemia, Malaria, and Case Fatality Among Children Hospitalized With Fever in Dar es Salaam, Tanzania 

      Moyo, Sabrina John; Manyahi, Joel; Blomberg, Bjørn; Tellevik, Marit Gjerde; Masoud, Nahya Salim; Aboud, Said; Manji, Karim; Roberts, Adam P.; Hanevik, Kurt; Mørch, Kristine; Langeland, Nina (Journal article; Peer reviewed, 2020)
      Background: Febrile illness is the commonest cause of hospitalization in children <5 years in sub-Saharan Africa, and bacterial bloodstream infections and malaria are major causes of death. Methods: From March 2017 to ...

    • Bacteria and fungi in acute cholecystitis. A prospective study comparing next generation sequencing to culture 

      Dyrhovden, Ruben; Øvrebø, Kjell Kåre; Nordahl, Magnus Vie; Nygaard, Randi M.; Ulvestad, Elling; Kommedal, Øyvind (Peer reviewed; Journal article, 2020)
      Objectives: Guidelines for antibiotic treatment of acute cholecystitis are based on studies using culture techniques for microbial identification. Microbial culture has well described limitations and more comprehensive ...

    • The bacterial aetiology of pleural empyema. A descriptive and comparative metagenomic study 

      Dyrhovden, Ruben; Nygaard, RM; Patel, R; Ulvestad, Elling; Kommedal, Øyvind (Peer reviewed; Journal article, 2019)
      Objectives: The view of pleural empyema as a complication of bacterial pneumonia is changing because many patients lack evidence of underlying pneumonia. To further our understanding of pathophysiological mechanisms, we ...

    • Bacterial Findings in Infected Hip Joint Replacements in Patients with Rheumatoid Arthritis and Osteoarthritis: A Study of 318 Revisions for Infection Reported to the Norwegian Arthroplasty Register 

      Schrama, Johannes Cornelis; Lutro, Olav; Langvatn, Håkon; Hallan, Geir; Espehaug, Birgitte; Sjursen, Haakon; Engesæter, Lars B.; Fevang, Bjørg Tilde Svanes (Peer reviewed; Journal article, 2012)
      High rates of Staphylococcus aureus are reported in prosthetic joint infection (PJI) in rheumatoid arthritis (RA). RA patients are considered to have a high risk of infection with bacteria of potentially oral or dental ...

    • Baked cod consumption delayed the development of kidney and liver dysfunction and affected plasma amino acid concentrations, but did not affect blood pressure, blood glucose or liver triacylglycerol concentrations in obese fa/fa Zucker rats. 

      Vikøren, Linn A.; Drotningsvik, Aslaug; Midttun, Øivind; McCann, Adrian; Bergseth, Marthe Tønder; Austgulen, Maren H.; Mellgren, Gunnar; Ueland, Per Magne; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2021)
      Obesity is associated with changes in amino acid metabolism, and studies show that ingestion of fish proteins influence amino acid composition in plasma and urine, in addition to affecting risk factors for metabolic syndrome. ...

    • Baseline frailty status and outcomes important for shared decision‑making in older adults receiving transcatheter aortic valve implantation, a prospective observational study 

      Skaar, Elisabeth; Øksnes, Anja; Eide, Leslie SP; Norekvål, Tone Merete; Ranhoff, Anette Hylen; Nordrehaug, Jan Erik; Forman, Daniel Edward; Schoennberger, Andreas W.; Hufthammer, Karl Ove; Kuiper, Karel Kier-Jan; Bleie, Øyvind; Packer, Erik; Langørgen, Jørund; Haaverstad, Rune; Schaufel, Margrethe Aase (Journal article; Peer reviewed, 2021)
      Aims The objective of this study was to examine baseline frailty status (including cognitive deficits) and important clinical outcomes, to inform shared decision-making in older adults receiving transcatheter aortic valve ...

    • Basosquamous Basal Cell Carcinoma with Bone Marrow Metastasis 

      Thunestvedt, Lise Mayrin Økland; Helgeland, Lars; Bachmann, Ingeborg Margrethe; Karlsdottir, Åsa; Haslerud, Torjan Magne; Reikvam, Håkon (Journal article; Peer reviewed, 2022-03-23)
      Basal cell carcinoma (BCC) is the most common cancer in Caucasians. It is slow growing and rarely metastasizes. If left untreated over time, invasive growth can occur. We present a patient case with a primary BCC located ...

    • Bedtime Salivary Cortisol as a Screening Test for Cushing Syndrome in Children 

      Ueland, Grethe Åstrøm; Kellmann, Ralf; Davidsen, Melissa Jørstad; Viste, Kristin; Husebye, Eystein Sverre; Almås, Bjørg; Storr, Helen L.; Sagen, Jørn Vegard; Mellgren, Gunnar; Juliusson, Pétur Benedikt; Methlie, Paal (Journal article; Peer reviewed, 2021)
      Background Diagnosing Cushing syndrome (CS) can be challenging. The 24-hour urine free cortisol (UFC) measurement is considered gold standard. This is a laborious test, dependent on correct urine collection. Late-night ...

    • Behovsmedisinering i sykehjem - forskrivning, bruk og dokumentasjon av effekt 

      Rønningen, Stine Wang (Master thesis, 2011-05-20)
      Fokus på legemiddelbehandling i sykehjem har økt i senere tid. Det har imidlertid i mindre grad vært sett på hva som forskrives og gis til pasientene ved behov. Avgjørelser rundt bruk og håndtering av behovslegemidler ...

    • The Bergen 4-Day Treatment for Panic Disorder: A Pilot Study 

      Hansen, Bjarne; Kvale, Gerd; Hagen, Kristen; Hjelle, Kay Morten; Solem, Stian; Bø, Beate Hatlelid; Øst, Lars Gøran (Peer reviewed; Journal article, 2018-06-26)
      The current article reports on the findings from a pilot treatment study on panic disorder (PD) with or without agoraphobia. Consecutively referred patients were included and treated with the Bergen 4-day treatment format. ...

    • Betaine as a determinant of postmethionine load total plasma homocysteine before and after B-Vitamin supplementation 

      Holm, Pål Ivar; Bleie, Øyvind; Ueland, Per Magne; Lien, Ernst Asbjørn; Refsum, Helga; Nordrehaug, Jan Erik; Nygård, Ottar (Peer reviewed; Journal article, 2004)
      Objective—Betaine is a substrate in the betaine– homocysteine methyltransferase reaction, converting homocysteine to methionine. There are only sparse data on plasma betaine as a determinant of the plasma total homocysteine ...

    • Beyond sleep duration: Sleep timing as a risk factor for childhood obesity 

      Skjåkødegård, Hanna Flækøy; Danielsen, Yngvild Sørebø; Frisk, Bente; Hystad, Sigurd William; Roelants, Mathieu; Pallesen, Ståle; Conlon, Rachel; Wilfley, Denise E.; Juliusson, Petur Benedikt (Journal article; Peer reviewed, 2021)
      Background: Ample evidence attests to the relationship between short sleep duration, sleep problems and childhood obesity. However, few studies have examined the association between sleep timing and obesity in children. ...

    • Bi-specific TCR-anti CD3 redirected T-cell targeting of NY-ESO-1- and LAGE-1-positive tumors 

      McCormack, Emmet; Adams, Katherine J.; Hassan, Namir J.; Kotian, Akhil; Lissin, Nikolai M.; Sami, Malkit; Mujic, Maja; Osdal, Tereza; Gjertsen, Bjørn Tore; Baker, Deborah; Powlesland, Alex S.; Aleksic, Milos; Vuidepot, Annelise; Morteau, Olivier; Sutton, Deborah H.; June, Carl H.; Kalos, Michael; Ashfield, Rebecca; Jakobsen, Bent K. (Peer reviewed; Journal article, 2012-12)
      NY-ESO-1 and LAGE-1 are cancer testis antigens with an ideal profile for tumor immunotherapy, combining up-regulation in many cancer types with highly restricted expression in normal tissues and sharing a common HLA-A*0201 ...

    • Bidirectional genetic overlap between autism spectrum disorder and cognitive traits 

      Hope, Sigrun; Shadrin, Alexey; Lin, Aihua; Bahrami, Shahram; Rødevand, Linn; Frei, Oleksandr; Hübenette, Saira Jameela; Cheng, Weiqiu; Hindley, Guy; Nag, Heidi Elisabeth; Ulstein, Line; Efrim-Budisteanu, Magdalena; O’Connell, Kevin; Dale, Anders; Djurovic, Srdjan; Nærland, Terje; Andreassen, Ole (Journal article; Peer reviewed, 2023)
      Autism spectrum disorder (ASD) is a highly heritable condition with a large variation in cognitive function. Here we investigated the shared genetic architecture between cognitive traits (intelligence (INT) and educational ...

    • Bile Acid Profiles in Primary Sclerosing Cholangitis and their Ability to Predict Hepatic Decompensation 

      Mousa, Omar Y; Juran, Brian D; McCauley, Bryan M.; Vesterhus, Mette; Folseraas, Trine; Turgeon, Coleman T.; Ali, Ahmad; Schlicht, Erik M; Atkinson, Elizabeth J; Hu, Chang; Harnois, Denise; Carey, Elizabeth J; Gossard, Andrea A; Oglesbee, Devin; Eaton, John E; LaRusso, Nicholas F.; Gores, Gregory J.; Karlsen, Tom Hemming; Lazaridis, Konstantinos N. (Journal article; Peer reviewed, 2021)
      Background and Aims: Altered bile acid (BA) homeostasis is an intrinsic facet of cholestatic liver diseases, but clinical usefulness of plasma BA assessment in primary sclerosing cholangitis (PSC) remains understudied. We ...

    • Bimodal expression of potential drug target CLL-1 (CLEC12A) on CD34+ blasts of AML patients 

      Ngai, Lok Lam; Ma, Connie Y.; Maguire, Orla; Do, An D.; Robert, Alberto; Logan, Aaron C.; Griffiths, Elizabeth A.; Nemeth, Michael J.; Green, Cherie; Pourmohamad, Tony; van Kuijk, Bo J.; Snel, Alexander N.; Kwidama, Zinia W.; Venniker-Punt, Bianca; Cooper, James; Manz, Markus G.; Gjertsen, Bjørn Tore; Smit, Linda; Ossenkoppele, Gert J.; Janssen, Jeroen J. W. M.; Cloos, Jacqueline; Sumiyoshi, Teiko (Journal article; Peer reviewed, 2021)
      Objectives This study aims to retrospectively assess C-lectin-like molecule 1 (CLL-1) bimodal expression on CD34+ blasts in acute myeloid leukemia (AML) patients (total N = 306) and explore potential CLL-1 bimodal ...