• Bruk av legemidler mot diabetes og depresjon i 2004 og 2009. Prevalens, sambruk, og risiko 

      Schwensen, Ida Cathrin R (Master thesis, 2012-11-12)
      Farmakoepidemiologi er læren om legemiddelbruk i samfunnet. Ved hjelp av statistikk kan vi se nærmere på hvordan legemidler brukes av befolkningen og om det finnes et mønster i denne bruken. Diabetes og depresjon er begge ...
    • Bruken av antidiabetika i Norge for perioden 2004-2010. En reseptregisterstudie 

      Endresen, Helle Nærsnes (Master thesis, 2011-05-20)
      For å etablere gode rutiner for behandling av diabetes finnes det i dag kliniske retningslinjer. Kjernen i disse er først å benytte seg av veldokumenterte billige alternativer fremfor nye, dyrere og mindre dokumenterte ...
    • Burden and characteristics of the comorbidity tuberculosis - diabetes in Europe : TBnet prevalence survey and case-control study 

      Sane Schepisi, Monica; Navarra, Assunta; Altet Gómez, Maria de las Nieves; Dudnyk, Andrii; Dyrhol-Riise, Anne Ma; Esteban, Jaime; Giorgetti, Pier Francesco; Gualano, Gina; Guglielmetti, Lorenzo; Heyckendorf, Jan; Kaluzhenina, Anna; Lange, Berit; Lange, Christoph; Manika, Katerina; Miah, Jalal; Nanovic, Zorica; Pontali, Emanuele; Prego, Monica Rios; Solovič, Ivan; Tiberi, Simon; Palmieri, Fabrizio; Girardi, Enrico (Peer reviewed; Journal article, 2019-01)
      Background: The growing burden of diabetes mellitus (DM) is posing a threat to global tuberculosis (TB) control. DM triples the risk of developing TB, modifies the presenting features of pulmonary TB, and worsens TB treatment ...
    • Burden of bloodstream infection in an area of Mid-Norway 2002-2013: A prospective population-based observational study 

      Mehl, Arne; Åsvold, Bjørn Olav; Lydersen, Stian; Paulsen, Julie; Solligård, Erik; Damås, Jan Kristian; Harthug, Stig; Edna, Tom-Harald (Peer reviewed; Journal article, 2017-03-11)
      Background: Studies from several countries indicate that the incidence and mortality of bloodstream infection (BSI) have been increasing over time. Methods: We studied the burden of disease and death related to BSI in a ...
    • Burden of treatment in patients with chronic heart failure – A cross-sectional study 

      Nordfonn, Oda Karin; Morken, Ingvild Margreta; Bru, Lars Edvin; Larsen, Alf Inge; Husebø, Anne Marie Lunde (Journal article; Peer reviewed, 2021)
      Background Patients with heart failure (HF) must manage both a demanding treatment regimen and self-care, which may lead to a burden of treatment. The purpose of this study was to assess the levels of burdens from treatment ...
    • CA-125 levels are predictive of survival in low-grade serous ovarian cancer—A multicenter analysis 

      Wohlmuth, Christoph; Djedovic, Vladimir; Kjær, Susanne K.; Jensen, Allan; Glasspool, Rosalind; Roxburgh, Patricia; Defazio, Anna; Johnatty, Sharon E.; Webb, Penelope M.; Modugno, Francesmary; Lambrechts, Diether; Schildkraut, Joellen M.; Berchuck, Andrew; Thomsen, Liv Cecilie Vestrheim; Bjørge, Line; Høgdall, Estrid; Høgdall, Claus K.; Goode, Ellen L.; Winham, Stacey J.; Matsuo, Keitaro; Karlan, Beth Y.; Lester, Jenny; Goodman, Marc T.; Thompson, Pamela J.; Pejovic, Tanja; Riggan, Marjorie J.; Lajkosz, Katherine; Tone, Alicia; May, Taymaa (Journal article; Peer reviewed, 2022-04-13)
      Objective: Studies on low-grade serous ovarian cancer (LGSC) are limited by a low number of cases. The aim of this study was to define the prognostic significance of age, stage, and CA-125 levels on survival in a ...
    • Ca-EDTA restores the activity of ceftazidime-avibactam or aztreonam against carbapenemase-producing Klebsiella pneumoniae infections 

      Wannigama, Dhammika Leshan; Sithu Shein, Aye Mya; Hurst, Cameron; Monk, Peter N.; Hongsing, Parichart; Phattharapornjaroen, Phatthranit; Fox Ditcham, William Graham; Ounjai, Puey; Saethang, Thammakorn; Chantaravisoot, Naphat; Wapeesittipan, Pattama; Luk-in, Sirirat; Sae-Joo, Sasipen; Nilgate, Sumanee; Rirerm, Ubolrat; Tanasatitchai, Chanikan; Kueakulpattana, Naris; Laowansiri, Matchima; Liao, Tingting; Kupwiwat, Rosalyn; Rojanathanes, Rojrit; Ngamwongsatit, Natharin; Tungsanga, Somkanya; Leelahavanichkul, Asada; Devanga Ragupathi, Naveen Kumar; Badavath, Vishnu Nayak; Hosseini Rad, S.M. Ali; Kanjanabuch, Talerngsak; Hirankarn, Nattiya; Storer, Robin James; Cui, Longzhu; Amarasiri, Mohan; Ishikawa, Hitoshi; Higgins, Paul G.; Stick, Stephen M.; Kicic, Anthony; Chatsuwan, Tanittha; Abe, Shuichi (Journal article; Peer reviewed, 2023)
      Developing an effective therapy to overcome carbapenemase-positive Klebsiella pneumoniae (CPKp) is an important therapeutic challenge that must be addressed urgently. Here, we explored a Ca-EDTA combination with aztreonam ...
    • CACNA1D overexpression and voltage-gated calcium channels in prostate cancer during androgen deprivation 

      McKerr, Niamh; Mohd-Sarip, Adone; Dorrian, Hannah; Breen, Conor; A. James, Jacqueline; McQuaid, Stephen; Mills, Ian Geoffrey; McCloskey, Karen D. (Journal article; Peer reviewed, 2023)
      Prostate cancer is often treated by perturbing androgen receptor signalling. CACNA1D, encoding CaV1.3 ion channels is upregulated in prostate cancer. Here we show how hormone therapy affects CACNA1D expression and CaV1.3 ...
    • Cadmium, lead and mercury in Norwegian obese patients before and 12 months after bariatric surgery 

      Mikalsen, Solveig Meyer; Bjørke-Monsen, Anne Lise; Flaten, Trond Peder; Whist, Jon Elling; Aaseth, Jan (Peer reviewed; Journal article, 2019)
      Purpose Previous studies have suggested a role for the toxic elements lead (Pb), mercury (Hg) and cadmium (Cd) in the development of insulin resistance and hypertension. Increased blood Pb levels have been reported after ...
    • Calprotectin (S100A8/A9) and S100A12 in inflammatory arthritis : clinical and epidemiological studies of rheumatoid and psoriatic arthritis 

      Madland, Tor Magne (Doctoral thesis, 2007-12-14)
      Rheumatoid- and psoriatic arthritis (RA and PsA) are the two most prevalent inflammatory joint diseases in Caucasian. Different biomarkers in peripheral blood may contribute in the diagnostic and prognostic process, as ...
    • Calprotectin (S100A8/A9) has the strongest association with ultrasound-detected synovitis and predicts response to biologic treatment: results from a longitudinal study of patients with established rheumatoid arthritis 

      Nordal, Hilde Haugedal; Brokstad, Karl Albert; Solheim, Magne; Halse, Anne-Kristine; Kvien, Tore Kristian; Hammer, Hilde Berner (Peer reviewed; Journal article, 2017-01-12)
      Background: Calprotectin (S100A8/A9 or MRP8/14) and S100A12 (leukocyte-derived proteins), interleukin 6 (IL-6) and vascular endothelial growth factor (VEGF) are markers of inflammation and angiogenesis. Ultrasound (US) is ...
    • Calprotectin, a sensitive marker of inflammation, is robustly assessed in plasma from patients with early or established rheumatoid arthritis by use of different laboratory methods 

      Hammer, Hilde Berner; Pedersen, Sigve Lans; Jonsson, Maria Karolina; Mathsson-Alm, Linda; Gehring, Isabel; Sexton, Joseph; Haavardsholm, Espen A.; Askling, Johan (Journal article; Peer reviewed, 2023)
      Calprotectin (S100A8/S100A9, MRP8/MRP14) is a major leukocyte protein found to be more sensitive than C-Reactive Protein (CRP) and Erythrocyte Sedimentation Rate (ESR) as a marker of inflammation in patients with rheumatoid ...
    • Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines 

      Bredholt, Therese; Dimba, Elizabeth A. O.; Hagland, Hanne; Wergeland, Line; Skavland, Jørn; Fossan, Kjell Ove; Tronstad, Karl Johan; Johannessen, Anne Christine; Vintermyr, Olav Karsten; Gjertsen, Bjørn Tore (Peer reviewed; Journal article, 2009-11-13)
      Background: An organic extract of the recreational herb khat (Catha edulis Forsk.) triggers cell death in various leukemia cell lines in vitro. The chemotherapeutics camptothecin, a plant alkaloid topoisomerase I inhibitor, ...
    • Can spirometric norms be set using pre- or post- bronchodilator test results in older people? 

      Kato, Bernet; Gulsvik, Amund; Vollmer, William; Janson, Christer; Studnika, Michael; Buist, Sonia; Burney, Peter (Peer reviewed; Journal article, 2012-11-16)
      Background: Chronic Obstructive Pulmonary Disease (COPD) is defined by post-bronchodilator spirometry. Data on “normal values” come predominantly from pre-bronchodilator spirometry. The effects of this on diagnosis are ...
    • Can The Use of Electronic Journal Systems Replace Human Intervention By The Medicine Reconciliation Process? 

      Luong, André Huy Gia (Master thesis, 2016-05-20)
      Can the use of electronic journal systems replace human intervention by the medicine reconciliation process? By André Luong Keywords: Medicine/medication reconciliation, electronic journal systems/records, pharmacist ...
    • Can We Optimize Antibiotic Use in Norwegian Neonates? A Prospective Comparison Between a University Hospital and a District Hospital 

      Thaulow, Christian Magnus; Berild, Dag; Blix, Hege Salvesen; Brigtsen, Anne Karin; Myklebust, Tor Åge; Eriksen, Beate Horsberg (Peer reviewed; Journal article, 2019)
      Background: Worldwide, a large proportion of neonates are prescribed antibiotics without having infections leading to increased antimicrobial resistance, disturbance of the evolving microbiota, and increasing the risk of ...
    • Cancer awareness in the general population varies with sex, age and media coverage: A population-based survey with focus on gynecologic cancers 

      Fonnes, Tina; Telle, Ingrid Ovidia Moe; Forsse, David Erik; Falck, Runa; Trovik, Jone; Haldorsen, Ingfrid S.; Krakstad, Camilla (Journal article; Peer reviewed, 2021)
      Objectives There is a need for more knowledge about the public awareness and attitudes towards gynecologic cancers. We employed a research-purpose population-based citizen panel to assess how often people recall gynecologic ...
    • Cancer Predisposition Sequencing Reporter (CPSR): A flexible variant report engine for high-throughput germline screening in cancer 

      Nakken, Sigve; Saveliev, Vladislav; Hofmann, Oliver; Møller, Pål; Myklebost, Ola; Hovig, Eivind (Journal article; Peer reviewed, 2021)
      The value of high-throughput germline genetic testing is increasingly recognized inclinical cancer care. Disease-associated germline variants in cancer patients areimportant for risk management and surveillance, surgical ...
    • Candidate locus analysis of the TERT–CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk 

      Carvajal-Carmona, Luis G.; O'Mara, Tracy A.; Painter, Jodie N.; Lose, Felicity A.; Dennis, Joe; Michailidou, Kyriaki; Tyrer, Jonathan P; Ahmed, Shahana; Ferguson, Kaltin; Healey, Catherine S.; Pooley, Karen; Beesley, Jonathan; Cheng, Timothy; Jones, Angela; Howarth, Kimberley; Martin, Lynn; Gorman, Maggie; Hodgson, Shirley; Wentzensen, Nicholas; Fasching, Peter A.; Hein, Alexander; Beckmann, Matthias W.; Renner, Stefan P.; Dörk, Thilo; Hillemanns, Peter; Durst, Matthias; Runnebaum, Ingo; Lambrechts, Dieter; Coenegrachts, Lieve; Schrauwen, Stefanie; Amant, Frederic; Winterhoff, Boris; Dowdy, Sean C.; Goode, Ellen L.; Teoman, Attila; Salvesen, Helga Birgitte; Trovik, Jone; Njølstad, Tormund Salvesen; Werner, Henrica Maria Johanna; Scott, Rodney J.; Ashton, Katie; Proietto, Tony; Otton, Geoffrey; Wersäll, Ofra; Mints, Miriam; Tham, Emma; Hall, Per; Czene, Kamila; Liu, Jianjun; Li, Jingmei; Hopper, John L.; Southey, Melissa C.; Ekici, Arif B.; Ruebner, Matthias; Johnson, Nichola; Peto, Julian; Burwinkel, Barbara; Marme, Frederik; Brenner, Hermann; Dieffenbach, Aida Karina; Meindl, Alfons; Brauch, Hiltrud; Lindblom, Annika; Depreeuw, Jeroen; Moisse, Matthieu; Chang-Claude, Jenny; Rudolph, Anja; Couch, Fergus J.; Olson, Janet E.; Giles, Graham G.; Bruinsma, Fiona; Cunningham, Julie M.; Fridley, Brooke L.; Børresen-Dale, Anne-Lise; Kristensen, Vessela N.; Cox, Angela; Swerdlow, Anthony J.; Orr, Nicholas; Bolla, Manjeet K.; Wang, Qin; Weber, Rachel Palmieri; Chen, Zhihua; Shah, Mitul; Pharoah, Paul D.P.; Dunning, Alison M.; Tomlinson, Ian; Easton, Douglas F.; Spurdle, Amanda B.; Thompson, Deborah J. (Peer reviewed; Journal article, 2014-12-09)
      Several studies have reported associations between multiple cancer types and single-nucleotide polymorphisms (SNPs) on chromosome 5p15, which harbours TERT and CLPTM1L, but no such association has been reported with ...
    • Candidate markers for stratification and classification in rheumatoid arthritis 

      Bader, Lucius; Gullaksen, Stein-Erik; Blaser, Nello; Brun, Morten; Bringeland, Gerd Haga; Sulen, Andre; Gjesdal, Clara Gram; Vedeler, Christian A.; Gavasso, Sonia (Peer reviewed; Journal article, 2019-07-05)
      Rheumatoid arthritis (RA) is a chronic autoimmune, inflammatory disease, characterized by synovitis in small- and medium-sized joints and, if not treated early and efficiently, joint damage, and destruction. RA is a ...