Blar i Department of Clinical Science på tittel
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The contribution of functional HNF1A variants and polygenic susceptibility to risk of type 2 diabetes in ancestrally diverse populations
(Journal article; Peer reviewed, 2023)Aims/hypothesis: We examined the contribution of rare HNF1A variants to type 2 diabetes risk and age of diagnosis, and the extent to which their impact is affected by overall genetic susceptibility, across three ancestry ... -
Conundrums in the breathless athlete; exercise-induced laryngeal obstruction or asthma?
(Journal article; Peer reviewed, 2022)Purpose: Exercise-induced bronchoconstriction (EIB) and exercise-induced laryngeal obstruction (EILO) are the two disorders commonly considered when athletes complain of exertional dyspnea. They are highly different but ... -
Convergence of virulence and MDR in a single plasmid vector in MDR Klebsiella pneumoniae ST15
(Peer reviewed; Journal article, 2019)Background: MDR and hypervirulence (hv) are typically observed in separate Klebsiella pneumoniae populations. However, convergent strains with both properties have been documented and potentially pose a high risk to public ... -
Coordination of Metabolism and Virulence Factors Expression of Extraintestinal Pathogenic Escherichia coli Purified from Blood Cultures of Patients with Sepsis
(Peer reviewed; Journal article, 2016-09)One of the trademarks of extraintestinal pathogenic Escherichia coli is adaptation of metabolism and basic physiology to diverse host sites. However, little is known how this common human pathogen adapts to permit survival ... -
COPD - do the right thing
(Journal article; Peer reviewed, 2021)A gap exists between guidelines and real-world clinical practice for the management and treatment of chronic obstructive pulmonary disease (COPD). Although this has narrowed in the last decade, there is room for improvement ... -
Coping with a disruptive life caused by obstetric fistula: Perspectives from Malawian women
(Peer reviewed; Journal article, 2019)Background: The main symptom of obstetric fistula is urinary and or fecal incontinence. Incontinence, regardless of the type is debilitating, socially isolating, and psychologically depressing. The objective of this study ... -
Copy number variants (CNVs): a powerful tool for iPSC-based modelling of ASD
(Journal article; Peer reviewed, 2020)Patients diagnosed with chromosome microdeletions or duplications, known as copy number variants (CNVs), present a unique opportunity to investigate the relationship between patient genotype and cell phenotype. CNVs have ... -
The core clock transcription factor BMAL1 drives circadian β-cell proliferation during compensatory regeneration of the endocrine pancreas
(Journal article; Peer reviewed, 2020)Circadian clocks in pancreatic islets participate in the regulation of glucose homeostasis. Here we examined the role of these timekeepers in β-cell regeneration after the massive ablation of β cells by doxycycline-induced ... -
Correlating local and systemic tumor-associated inflammation in colon cancer : CRP and the tumor immune microenvironment
(Doctoral thesis, 2023-12-14)Bakgrunn: Markører for systemisk inflammasjon er assosiert med dårlig prognose i en rekke ulike kreft typer, inkludert tykk- og endetarms kreft (CRC). I dette prosjektet fokuseres på betydningen av systemisk tumor-assosiert ... -
Correlation analysis of two-dimensional gel electrophoretic protein patterns and biological variables
(BMC Bioinformatics 7(198), Peer reviewed; Journal article, 2006-04-10)Background: Two-dimensional gel electrophoresis (2DE) is a powerful technique to examine post-translational modifications of complexly modulated proteins. Currently, spot detection is a necessary step to assess relations ... -
Correlation between Murmurs and Echocardiographic Findings; From an Imaging Cardiologist Point of View
(Journal article; Peer reviewed, 2023)A heart murmur in adults is a common reason for referral for echocardiography at most general cardiology clinics in Europe. A murmur may indicate either a mild age-related valvular calcification or regurgitation, or represent ... -
Cortical thickness changes after computerized working memory training in patients with mild cognitive impairment
(Journal article; Peer reviewed, 2022-04-04)Background: Adaptive computerized working memory (WM) training has shown favorable effects on cerebral cortical thickness as compared to non-adaptive training in healthy individuals. However, knowledge of WM training-related ... -
Corticosteroids and superinfections in COVID-19 patients on invasive mechanical ventilation
(Journal article; Peer reviewed, 2022)Objectives To determine the incidence and characteristics of superinfections in mechanically ventilated COVID-19 patients, and the impact of dexamethasone as standard therapy. Methods This multicentre, observational, ... -
Cost effectiveness of adding budesonide/formoterol to tiotropium in COPD in four Nordic countries
(Peer reviewed; Journal article, 2013-11)Objective: Assess the cost effectiveness of budesonide/formoterol (BUD/FORM) Turbuhaler®+tiotropium (TIO) HandiHaler® vs. placebo (PBO)+TIO in patients with chronic obstructive pulmonary disease (COPD) eligible for inhaled ... -
Cost-Effectiveness of Vaccination of Older Adults with an MF59®-Adjuvanted Quadrivalent Influenza Vaccine Compared to Standard-Dose and High-Dose Vaccines in Denmark, Norway, and Sweden
(Journal article; Peer reviewed, 2023)Individuals aged 65 years and above are at increased risk of complications and death from influenza compared with any other age group. Enhanced vaccines, as the MF59®-adjuvanted quadrivalent influenza vaccine (aQIV) and ... -
Counting Mycobacteria in Infected Human Cells and Mouse Tissue: A Comparison between qPCR and CFU
(Peer reviewed; Journal article, 2012-04-19)Due to the slow growth rate and pathogenicity of mycobacteria, enumeration by traditional reference methods like colony counting is notoriously time-consuming, inconvenient and biohazardous. Thus, novel methods that rapidly ... -
The course and determinants of post-traumatic stress over 12 months after hospitalization for COVID-19
(Journal article; Peer reviewed, 2022)Objective: To assess the trajectory of symptoms and symptom-defined post-traumatic stress disorder (PTSD) from 1.5 to 12 months after hospitalization for COVID-19 and determine risk factors for persistent symptoms and ... -
Covariables of Myocardial Function in Women and Men with Increased Body Mass Index
(Journal article; Peer reviewed, 2020)Introduction Sex-difference in types of cardiac organ damage has been reported in subjects with increased body mass index (BMI). However less is known about sex-differences in left ventricular (LV) myocardial function ... -
Covid-19 hos pasienter med kronisk inflammatorisk leddsykdom
(Journal article; Peer reviewed, 2021)BAKGRUNN Siden pasienter med kronisk inflammatorisk leddsykdom kan være mer utsatt for infeksjoner, ønsket vi å undersøke forekomsten av covid-19 i denne gruppen og se om forhold ved den revmatiske sykdommen, pasienten ... -
COVID-19 myocarditis and postinfection Bell’s palsy
(Journal article; Peer reviewed, 2021)Here we present the case of a 37-year-old previously healthy man who developed fever, headache and a unilateral, painful neck swelling while working offshore. He had no known contact with anyone with COVID-19; however, due ...