Blar i Department of Clinical Science på tittel

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    • COPD - do the right thing 

      Sandelowsky, Hanna; Weinreich, Ulla Møller; Aarli, Bernt Bøgvald; Sundh, Josefin; Høines, Kristian Jong; Stratelis, Georgios; Løkke, Anders; Janson, Christer; Jensen, Christian; Larsson, Kjell (Journal article; Peer reviewed, 2021)
      A gap exists between guidelines and real-world clinical practice for the management and treatment of chronic obstructive pulmonary disease (COPD). Although this has narrowed in the last decade, there is room for improvement ...

    • Coping with a disruptive life caused by obstetric fistula: Perspectives from Malawian women 

      Changole, Josephine; Combs Thorsen, Viva; Trovik, Jone; Kafulafula, Ursula; Sundby, Johanne (Peer reviewed; Journal article, 2019)
      Background: The main symptom of obstetric fistula is urinary and or fecal incontinence. Incontinence, regardless of the type is debilitating, socially isolating, and psychologically depressing. The objective of this study ...

    • Copy number variants (CNVs): a powerful tool for iPSC-based modelling of ASD 

      Drakulic, Danijela; Djurovic, Srdjan; Syed, Yasir Ahmed; Trattaro, Sebastiano; Caporale, Nicolò; Falk, Anna; Ofir, Rivka; Heine, Vivi M.; Chawner, Samuel J.R.A.; Rodriguez-Moreno, Antonio; van den Bree, Marianne B.M.; Testa, Giuseppe; Petrakis, Spyros; Harwood, Adrian J. (Journal article; Peer reviewed, 2020)
      Patients diagnosed with chromosome microdeletions or duplications, known as copy number variants (CNVs), present a unique opportunity to investigate the relationship between patient genotype and cell phenotype. CNVs have ...

    • The core clock transcription factor BMAL1 drives circadian β-cell proliferation during compensatory regeneration of the endocrine pancreas 

      Petrenko, Volodymyr; Stolovich-Rain, Miri; Vandereycken, Bart; Giovannoni, Laurianne; Storch, Kai-Florian; Dor, Yuval; Chera, Simona; Dibner, Charna (Journal article; Peer reviewed, 2020)
      Circadian clocks in pancreatic islets participate in the regulation of glucose homeostasis. Here we examined the role of these timekeepers in β-cell regeneration after the massive ablation of β cells by doxycycline-induced ...

    • Correlating local and systemic tumor-associated inflammation in colon cancer : CRP and the tumor immune microenvironment 

      Køstner, Anne Helene (Doctoral thesis, 2023-12-14)
      Bakgrunn: Markører for systemisk inflammasjon er assosiert med dårlig prognose i en rekke ulike kreft typer, inkludert tykk- og endetarms kreft (CRC). I dette prosjektet fokuseres på betydningen av systemisk tumor-assosiert ...

    • Correlation analysis of two-dimensional gel electrophoretic protein patterns and biological variables 

      Van Belle, Werner; Ånensen, Nina; Haaland, Ingvild; Bruserud, Øystein; Høgda, Kjell-Arild; Gjertsen, Bjørn Tore (BMC Bioinformatics 7(198), Peer reviewed; Journal article, 2006-04-10)
      Background: Two-dimensional gel electrophoresis (2DE) is a powerful technique to examine post-translational modifications of complexly modulated proteins. Currently, spot detection is a necessary step to assess relations ...

    • Correlation between Murmurs and Echocardiographic Findings; From an Imaging Cardiologist Point of View 

      Saeed, Sahrai; Mohamed Ali, Abukar; Wasim, Daanyaal; Risnes, Ivar; Urheim, Stig (Journal article; Peer reviewed, 2023)
      A heart murmur in adults is a common reason for referral for echocardiography at most general cardiology clinics in Europe. A murmur may indicate either a mild age-related valvular calcification or regurgitation, or represent ...

    • Cortical thickness changes after computerized working memory training in patients with mild cognitive impairment 

      Hol, Haakon Ramsland; Flak, Marianne Møretrø; Chang, Linda; Løhaugen, Gro; Bjuland, Knut Jørgen; Rimol, Lars Morten; Engvig, Andreas; Skranes, Jon Sverre; Ernst, Thomas; Madsen, Bengt-Ove; Hernes, Susanne M S (Journal article; Peer reviewed, 2022-04-04)
      Background: Adaptive computerized working memory (WM) training has shown favorable effects on cerebral cortical thickness as compared to non-adaptive training in healthy individuals. However, knowledge of WM training-related ...

    • Corticosteroids and superinfections in COVID-19 patients on invasive mechanical ventilation 

      Søvik, Signe; Barrat-Due, Andreas; Kåsine, Trine; Olasveengen, Theresa M.; Strand, Marianne Wigernes; Tveita, Anders Aune; Berdal, Jan-Erik; Lehre, Martin Andreas; Lorentsen, Torleif; Heggelund, Lars; Stenstad, Tore; Ringstad, Jetmund; Müller, Fredrik; Aukrust, Pål; Holter, Jan Cato; Nordøy, Ingvild (Journal article; Peer reviewed, 2022)
      Objectives To determine the incidence and characteristics of superinfections in mechanically ventilated COVID-19 patients, and the impact of dexamethasone as standard therapy. Methods This multicentre, observational, ...

    • Cost effectiveness of adding budesonide/formoterol to tiotropium in COPD in four Nordic countries 

      Nielsen, Rune; Kankaanranta, Hannu; Bjermer, Leif; Lange, Peter; Arnetorp, Sofie; Hedegaard, Morten; Stenling, Anna; Mittmann, Nicole (Peer reviewed; Journal article, 2013-11)
      Objective: Assess the cost effectiveness of budesonide/formoterol (BUD/FORM) Turbuhaler®+tiotropium (TIO) HandiHaler® vs. placebo (PBO)+TIO in patients with chronic obstructive pulmonary disease (COPD) eligible for inhaled ...

    • Cost-Effectiveness of Vaccination of Older Adults with an MF59®-Adjuvanted Quadrivalent Influenza Vaccine Compared to Standard-Dose and High-Dose Vaccines in Denmark, Norway, and Sweden 

      Jacob, Jorge; Biering-Sørensen, Tor; Holger Ehlers, Lars; Edwards, Christina Hansen; Mohn, Kristin Greve-Isdahl; Nilsson, Anna; Hjelmgren, Jonas; Ma, Wenkang; Sharma, Yuvraj; Ciglia, Emanuele; Mould-Quevedo, Joaquin (Journal article; Peer reviewed, 2023)
      Individuals aged 65 years and above are at increased risk of complications and death from influenza compared with any other age group. Enhanced vaccines, as the MF59®-adjuvanted quadrivalent influenza vaccine (aQIV) and ...

    • Counting Mycobacteria in Infected Human Cells and Mouse Tissue: A Comparison between qPCR and CFU 

      Pathak, Sharad; Awuh, Jane A.; Leversen, Nils Anders; Flo, Trude H.; Åsjø, Birgitta (Peer reviewed; Journal article, 2012-04-19)
      Due to the slow growth rate and pathogenicity of mycobacteria, enumeration by traditional reference methods like colony counting is notoriously time-consuming, inconvenient and biohazardous. Thus, novel methods that rapidly ...

    • The course and determinants of post-traumatic stress over 12 months after hospitalization for COVID-19 

      Stavem, Knut; Heir, Trond; Dammen, Toril; Brønstad, Eivind; Lerum, Tøri Vigeland; Durheim, Michael Thomas; Lund, Kristine Marie Aarberg; Aarli, Bernt Bøgvald; Einvik, Gunnar (Journal article; Peer reviewed, 2022)
      Objective: To assess the trajectory of symptoms and symptom-defined post-traumatic stress disorder (PTSD) from 1.5 to 12 months after hospitalization for COVID-19 and determine risk factors for persistent symptoms and ...

    • Covariables of Myocardial Function in Women and Men with Increased Body Mass Index 

      Pristaj, Nadia; Saeed, Sahrai; Midtbø, Helga Bergljot; Halland, Hilde; Matre, Knut; Gerdts, Eva (Journal article; Peer reviewed, 2020)
      Introduction Sex-difference in types of cardiac organ damage has been reported in subjects with increased body mass index (BMI). However less is known about sex-differences in left ventricular (LV) myocardial function ...

    • Covid-19 hos pasienter med kronisk inflammatorisk leddsykdom 

      Nystad, Tone Wikene; Hufthammer, Karl Ove; Buanes, Eirik Alnes; Bryne, Kjartan; Fevang, Bjørg Tilde Svanes (Journal article; Peer reviewed, 2021)
      BAKGRUNN Siden pasienter med kronisk inflammatorisk leddsykdom kan være mer utsatt for infeksjoner, ønsket vi å undersøke forekomsten av covid-19 i denne gruppen og se om forhold ved den revmatiske sykdommen, pasienten ...

    • COVID-19 myocarditis and postinfection Bell’s palsy 

      Dahl, Elin Hoffmann; Mosevoll, Knut Anders; Cramariuc, Dana; Vedeler, Christian Alexander; Blomberg, Bjørn (Journal article; Peer reviewed, 2021)
      Here we present the case of a 37-year-old previously healthy man who developed fever, headache and a unilateral, painful neck swelling while working offshore. He had no known contact with anyone with COVID-19; however, due ...

    • COVID-19 pandemic and mortality in nursing homes across USA and Europe up to October 2021 

      Aalto, Ulla L.; Pitkala, Kaisu H; Andersen-Ranberg, Karen; Bonin-Guillaume, Sylvie; Cruz-Jentoft, Alfonso J.; Eriksdotter, Maria; Gordon, Adam; Gosch, Markus; Holmerova, Iva; Kautiainen, Hannu; Kivipelto, Miia; Macijauskiene, Jurate; O’Neill, Desmond; Van Den Noortgate, Nele; Ranhoff, Anette Hylen; Schols, Jos M. G. A.; Singler, Katrin; Stankunas, Mindaugas; Ouslander, Joseph G. (Journal article; Peer reviewed, 2022)
      Purpose: We compared the prevalence of COVID-19 and related mortality in nursing homes (NHs) in 14 countries until October 2021. We explored the relationship between COVID-19 mortality in NHs with the average size of NHs ...

    • Cow Farmers’ Homes Host More Diverse Airborne Bacterial Communities Than Pig Farmers’ Homes and Suburban Homes 

      Abouelhana, Hesham Amin Mohamed; Šantl-Temkiv, Tina; Cramer, Christine; Vestergaard, Ditte V.; Holst, Gitte J.; Elholm, Grethe; Finster, Kai; Bertelsen, Randi Jacobsen; Schlünssen, Vivi; Sigsgaard, Torben; Marshall, Ian P. G. (Journal article; Peer reviewed, 2022)
      Living on a farm has been linked to a lower risk of immunoregulatory disorders, such as asthma, allergy, and inflammatory bowel disease. It is hypothesized that a decrease in the diversity and composition of indoor microbial ...

    • The COX- inhibitor indomethacin reduces Th1 effector and T regulatory cells in vitro in Mycobacterium tuberculosis infection 

      Tonby, Kristian; Wergeland, Ida; Lieske, Nora Valeska; Kvale, Dag; Tasken, Kjetil; Dyrhol-Riise, Anne Ma (Peer reviewed; Journal article, 2016-10-24)
      Background: Tuberculosis (TB) causes a major burden on global health with long and cumbersome TB treatment regimens. Host-directed immune modulating therapies have been suggested as adjunctive treatment to TB antibiotics. ...

    • Creatinine, total cysteine and uric acid are associated with serum retinol in patients with cardiovascular disease 

      Olsen, Thomas; Vinknes, Kathrine; Blomhoff, Rune; Lysne, Vegard; Midttun, Øivind; Dhar, Indu; Ueland, Per Magne; Svingen, Gard Frodahl Tveitevåg; Pedersen, Eva Ringdal; Drevon, Christian A; Refsum, Helga; Nygård, Ottar (Peer reviewed; Journal article, 2019-09-09)
      Purpose: We hypothesized that biomarkers and dietary factors related to cardiovascular disease risk were associated with serum retinol and evaluated these potential associations in patients with suspected coronary artery ...