• Cortical thickness changes after computerized working memory training in patients with mild cognitive impairment 

      Hol, Haakon Ramsland; Flak, Marianne Møretrø; Chang, Linda; Løhaugen, Gro; Bjuland, Knut Jørgen; Rimol, Lars Morten; Engvig, Andreas; Skranes, Jon Sverre; Ernst, Thomas; Madsen, Bengt-Ove; Hernes, Susanne M S (Journal article; Peer reviewed, 2022-04-04)
      Background: Adaptive computerized working memory (WM) training has shown favorable effects on cerebral cortical thickness as compared to non-adaptive training in healthy individuals. However, knowledge of WM training-related ...
    • Corticosteroids and superinfections in COVID-19 patients on invasive mechanical ventilation 

      Søvik, Signe; Barrat-Due, Andreas; Kåsine, Trine; Olasveengen, Theresa M.; Strand, Marianne Wigernes; Tveita, Anders Aune; Berdal, Jan-Erik; Lehre, Martin Andreas; Lorentsen, Torleif; Heggelund, Lars; Stenstad, Tore; Ringstad, Jetmund; Müller, Fredrik; Aukrust, Pål; Holter, Jan Cato; Nordøy, Ingvild (Journal article; Peer reviewed, 2022)
      Objectives To determine the incidence and characteristics of superinfections in mechanically ventilated COVID-19 patients, and the impact of dexamethasone as standard therapy. Methods This multicentre, observational, ...
    • Cost effectiveness of adding budesonide/formoterol to tiotropium in COPD in four Nordic countries 

      Nielsen, Rune; Kankaanranta, Hannu; Bjermer, Leif; Lange, Peter; Arnetorp, Sofie; Hedegaard, Morten; Stenling, Anna; Mittmann, Nicole (Peer reviewed; Journal article, 2013-11)
      Objective: Assess the cost effectiveness of budesonide/formoterol (BUD/FORM) Turbuhaler®+tiotropium (TIO) HandiHaler® vs. placebo (PBO)+TIO in patients with chronic obstructive pulmonary disease (COPD) eligible for inhaled ...
    • Cost-Effectiveness of Vaccination of Older Adults with an MF59®-Adjuvanted Quadrivalent Influenza Vaccine Compared to Standard-Dose and High-Dose Vaccines in Denmark, Norway, and Sweden 

      Jacob, Jorge; Biering-Sørensen, Tor; Holger Ehlers, Lars; Edwards, Christina Hansen; Mohn, Kristin Greve-Isdahl; Nilsson, Anna; Hjelmgren, Jonas; Ma, Wenkang; Sharma, Yuvraj; Ciglia, Emanuele; Mould-Quevedo, Joaquin (Journal article; Peer reviewed, 2023)
      Individuals aged 65 years and above are at increased risk of complications and death from influenza compared with any other age group. Enhanced vaccines, as the MF59®-adjuvanted quadrivalent influenza vaccine (aQIV) and ...
    • Counting Mycobacteria in Infected Human Cells and Mouse Tissue: A Comparison between qPCR and CFU 

      Pathak, Sharad; Awuh, Jane A.; Leversen, Nils Anders; Flo, Trude H.; Åsjø, Birgitta (Peer reviewed; Journal article, 2012-04-19)
      Due to the slow growth rate and pathogenicity of mycobacteria, enumeration by traditional reference methods like colony counting is notoriously time-consuming, inconvenient and biohazardous. Thus, novel methods that rapidly ...
    • The course and determinants of post-traumatic stress over 12 months after hospitalization for COVID-19 

      Stavem, Knut; Heir, Trond; Dammen, Toril; Brønstad, Eivind; Lerum, Tøri Vigeland; Durheim, Michael Thomas; Lund, Kristine Marie Aarberg; Aarli, Bernt Bøgvald; Einvik, Gunnar (Journal article; Peer reviewed, 2022)
      Objective: To assess the trajectory of symptoms and symptom-defined post-traumatic stress disorder (PTSD) from 1.5 to 12 months after hospitalization for COVID-19 and determine risk factors for persistent symptoms and ...
    • Covariables of Myocardial Function in Women and Men with Increased Body Mass Index 

      Pristaj, Nadia; Saeed, Sahrai; Midtbø, Helga Bergljot; Halland, Hilde; Matre, Knut; Gerdts, Eva (Journal article; Peer reviewed, 2020)
      Introduction Sex-difference in types of cardiac organ damage has been reported in subjects with increased body mass index (BMI). However less is known about sex-differences in left ventricular (LV) myocardial function ...
    • Covid-19 hos pasienter med kronisk inflammatorisk leddsykdom 

      Nystad, Tone Wikene; Hufthammer, Karl Ove; Buanes, Eirik Alnes; Bryne, Kjartan; Fevang, Bjørg Tilde Svanes (Journal article; Peer reviewed, 2021)
      BAKGRUNN Siden pasienter med kronisk inflammatorisk leddsykdom kan være mer utsatt for infeksjoner, ønsket vi å undersøke forekomsten av covid-19 i denne gruppen og se om forhold ved den revmatiske sykdommen, pasienten ...
    • COVID-19 myocarditis and postinfection Bell’s palsy 

      Dahl, Elin Hoffmann; Mosevoll, Knut Anders; Cramariuc, Dana; Vedeler, Christian Alexander; Blomberg, Bjørn (Journal article; Peer reviewed, 2021)
      Here we present the case of a 37-year-old previously healthy man who developed fever, headache and a unilateral, painful neck swelling while working offshore. He had no known contact with anyone with COVID-19; however, due ...
    • COVID-19 pandemic and mortality in nursing homes across USA and Europe up to October 2021 

      Aalto, Ulla L.; Pitkala, Kaisu H; Andersen-Ranberg, Karen; Bonin-Guillaume, Sylvie; Cruz-Jentoft, Alfonso J.; Eriksdotter, Maria; Gordon, Adam; Gosch, Markus; Holmerova, Iva; Kautiainen, Hannu; Kivipelto, Miia; Macijauskiene, Jurate; O’Neill, Desmond; Van Den Noortgate, Nele; Ranhoff, Anette Hylen; Schols, Jos M. G. A.; Singler, Katrin; Stankunas, Mindaugas; Ouslander, Joseph G. (Journal article; Peer reviewed, 2022)
      Purpose: We compared the prevalence of COVID-19 and related mortality in nursing homes (NHs) in 14 countries until October 2021. We explored the relationship between COVID-19 mortality in NHs with the average size of NHs ...
    • Cow Farmers’ Homes Host More Diverse Airborne Bacterial Communities Than Pig Farmers’ Homes and Suburban Homes 

      Abouelhana, Hesham Amin Mohamed; Šantl-Temkiv, Tina; Cramer, Christine; Vestergaard, Ditte V.; Holst, Gitte J.; Elholm, Grethe; Finster, Kai; Bertelsen, Randi Jacobsen; Schlünssen, Vivi; Sigsgaard, Torben; Marshall, Ian P. G. (Journal article; Peer reviewed, 2022)
      Living on a farm has been linked to a lower risk of immunoregulatory disorders, such as asthma, allergy, and inflammatory bowel disease. It is hypothesized that a decrease in the diversity and composition of indoor microbial ...
    • The COX- inhibitor indomethacin reduces Th1 effector and T regulatory cells in vitro in Mycobacterium tuberculosis infection 

      Tonby, Kristian; Wergeland, Ida; Lieske, Nora Valeska; Kvale, Dag; Tasken, Kjetil; Dyrhol-Riise, Anne Ma (Peer reviewed; Journal article, 2016-10-24)
      Background: Tuberculosis (TB) causes a major burden on global health with long and cumbersome TB treatment regimens. Host-directed immune modulating therapies have been suggested as adjunctive treatment to TB antibiotics. ...
    • Creatinine, total cysteine and uric acid are associated with serum retinol in patients with cardiovascular disease 

      Olsen, Thomas; Vinknes, Kathrine; Blomhoff, Rune; Lysne, Vegard; Midttun, Øivind; Dhar, Indu; Ueland, Per Magne; Svingen, Gard Frodahl Tveitevåg; Pedersen, Eva Ringdal; Drevon, Christian A; Refsum, Helga; Nygård, Ottar (Peer reviewed; Journal article, 2019-09-09)
      Purpose: We hypothesized that biomarkers and dietary factors related to cardiovascular disease risk were associated with serum retinol and evaluated these potential associations in patients with suspected coronary artery ...
    • A critical appraisal of the evidence for using cardiotocography plus ECG ST interval analysis for fetal surveillance in labor. Part I: The randomized controlled trials 

      Olofsson, Per; Ayres-de-Campos, Diogo; Kessler, Jörg; Tendal, Britta; Yli, Branislava Markovic; Devoe, Lawrence (Peer reviewed; Journal article, 2014-06)
      We reappraised the five randomized controlled trials that compared cardiotocography plus ECG ST interval analysis (CTG+ST) vs. cardiotocography. The numbers enrolled ranged from 5681 (Dutch randomized controlled trial) to ...
    • A critical appraisal of the evidence for using cardiotocography plus ECG ST interval analysis for fetal surveillance in labor. Part II: The meta-analyses 

      Olofsson, Per; Ayres-de-Campos, Diogo; Kessler, Jörg; Tendal, Britta; Yli, Branislava Markovic; Devoe, Lawrence (Peer reviewed; Journal article, 2014-06)
      We appraised the methodology, execution and quality of the five published meta-analyses that are based on the five randomized controlled trials which compared cardiotocography (CTG)+ST analysis to cardiotocography. The ...
    • Critical evaluation of the appetite test for children with severe acute malnutrition 

      Zangenberg, Mike; Abdissa, Alemseged; Johansen, Øystein Haarklau; Tesfaw, Getnet; Friis, Henrik; Briend, André; Eshetu, Beza; Kurtzhals, Jørgen Anders Lindholm; Girma, Tsinuel (Peer reviewed; Journal article, 2020)
      OBJECTIVES: The appetite test is used to risk-stratify for children with severe acute malnutrition (SAM) in in-patient or out-patient care. The test is recommended in guidelines despite lack of evidence. We evaluated its ...
    • Cross-reactivity of the CEDIA buprenorphine assay in drugs-of-abuse screening: influence of dose and metabolites of opioids 

      Berg, Jon Andsnes; Schjøtt, Jan; Fossan, Kjell Ove; Riedel, Bettina (Peer reviewed; Journal article, 2015-10-28)
      Purpose: The cloned enzyme donor immunoassay (CEDIA) for buprenorphine is applied for both urine drugs-of-abuse screening and compliance monitoring. Sensitivity, specificity, and optimal cutoff of this assay have differed ...
    • Cross-Species Functional Genomic Analysis Identifies Resistance Genes of the Histone Deacetylase Inhibitor Valproic Acid 

      Forthun, Rakel Brendsdal; SenGupta, Tanima; Skjeldam, Hanne Kim; Lindvall, Jessica Margareta; McCormack, Emmet; Gjertsen, Bjørn Tore (Peer reviewed; Journal article, 2012-11-14)
      The mechanisms of successful epigenetic reprogramming in cancer are not well characterized as they involve coordinated removal of repressive marks and deposition of activating marks by a large number of histone and DNA ...
    • Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders 

      Hindley, Guy; Drange, Ole Kristian; Lin, Aihua; Kutrolli, Gleda; Shadrin, Alexey; Parker, Nadine; O'Connell, Kevin Sean; Rødevand, Linn; Cheng, Weiqiu; Bahrami, Shahram; Karadag, Naz; Holen, Børge; Jaholkowski, Piotr Pawel; Woldeyohannes, Markos Tesfaye; Djurovic, Srdjan; Dale, Anders M.; Frei, Oleksandr; Ueland, Thor; Smeland, Olav Bjerkehagen; Andreassen, Ole (Journal article; Peer reviewed, 2023)
      C-reactive protein (CRP) tends to be elevated in individuals with psychiatric disorders. Recent findings have suggested a protective effect of the genetic liability to elevated CRP on schizophrenia risk and a causative ...
    • Crosstalk between HSF1 and HSF2 during the heat shock response in mouse testes 

      Korfanty, Joanna; Stokowy, Tomasz; Widlak, Piotr; Gogler-Piglowska, Agnieszka; Handschuh, Luiza; Podkowinski, Jan; Vydra, Natalia; Naumowicz, Anna; Toma-Jonik, Agnieszka; Widlak, Wieslawa (Peer reviewed; Journal article, 2014-12)
      Heat Shock Factor 1 (HSF1) is the primary transcription factor responsible for the response to cellularstress, while HSF2 becomes activated during development and differentiation, including spermatogen-esis. Although both ...