Now showing items 27-46 of 390

    • B cell specificity and pattern in primary Sjögren’s syndrome - Studies in humans and a murine model 

      Aqrawi, Lara Adnan (The University of Bergen, 2014-04-30)
      Sjögren’s syndrome (SS) is a chronic autoimmune disease characterised by focal inflammation of exocrine glands, particularly salivary and lacrimal glands. Here, mononuclear cells, including B cells, infiltrate the glands, ...
      Doctoral thesis
    • B vitamin and iron status during infancy 

      Torsvik, Ingrid Kristin (The University of Bergen, 2015-01-30)
      Adequate nutrition during infancy is essential to ensure normal growth and development. Since 2001, World Health Organization (WHO) has recommended exclusive breast-feeding for the first 6 months of life, which puts great ...
      Doctoral thesis
    • B vitamin treatments modify the risk of myocardial infarction associated with a MTHFD1 polymorphism in patients with stable angina pectoris 

      Ding, Yunpeng; Pedersen, Eva Ringdal; Johansson, Stefan; Gregory III, Jesse F.; Ueland, Per Magne; Svingen, Gard Frodahl Tveitevåg; Helgeland, Øyvind; Meyer, Klaus; Fredriksen, Åse; Nygård, Ottar (Elsevier, 2016-06)
      Background: Methylenetetrahydrofolate dehydrogenase (MTHFD1) catalyzes three sequential reactions that metabolize derivatives of tetrahydrofolate (THF) in folate-dependent one-carbon metabolism. Impaired MTHFD1 flux has ...
      Journal article
    • Bacterial Findings in Infected Hip Joint Replacements in Patients with Rheumatoid Arthritis and Osteoarthritis: A Study of 318 Revisions for Infection Reported to the Norwegian Arthroplasty Register 

      Schrama, Johannes Cornelis; Lutro, Olav; Langvatn, Håkon; Hallan, Geir; Espehaug, Birgitte; Sjursen, Haakon; Engesæter, Lars B.; Fevang, Bjørg Tilde Svanes (Hindawi, 2012)
      High rates of Staphylococcus aureus are reported in prosthetic joint infection (PJI) in rheumatoid arthritis (RA). RA patients are considered to have a high risk of infection with bacteria of potentially oral or dental ...
      Journal article
    • Biomarkers and Algorithms for the Diagnosis of Vitamin B12 Deficiency 

      Hannibal, Luciana; Lysne, Vegard; Bjørke-Monsen, Anne-Lise; Behringer, Sidney; Grünert, Sarah C.; Spiekerkoetter, Ute; Jacobsen, Donald W.; Blom, Henk J. (Frontiers, 2016-06-27)
      Vitamin B12 (cobalamin, Cbl, B12) is an indispensable water-soluble micronutrient that serves as a coenzyme for cytosolic methionine synthase (MS) and mitochondrial methylmalonyl-CoA mutase (MCM). Deficiency of Cbl, ...
      Journal article
    • Biomarkers and echocardiographic predictors of myocardial dysfunction in patients with hypertension 

      Bielecka-Dabrowa, Agata; Michalska-Kasiczak, Marta; Gluba, Anna; Ahmed, Ali; Gerdts, Eva; von Haehling, Stephan; Rysz, Jacek; Banach, Maciej (Nature Publishing Group, 2015-03-09)
      The study aimed to identify early echocardiographic and circulating biomarkers of heart failure (HF) in hypertensive patients with normal resting echocardiography. Echocardiography at rest and during exercise, and selected ...
      Journal article
    • BLR1 and FCGR1A transcripts in peripheral blood associate with the extent of intrathoracic tuberculosis in children and predict treatment outcome 

      Jenum, Synne; Bakken, Rasmus; Sivakumaran, Dhanasekaran; Mukherjee, Aparna; Lodha, Rakesh; Singh, Sarman; Singh, Varinder; Haks, Marielle C.; Ottenhoff, Tom H.M.; Kabra, Sushil Kumar; Doherty, Timothy Mark; Ritz, Christian; Grewal, Harleen (Nature Publishing Group, 2016-12-12)
      Biomarkers reflecting the extent of Mycobacterium tuberculosis-induced pathology and normalization during anti-tuberculosis treatment (ATT) would considerably facilitate trials of new treatment regimens and the identification ...
      Journal article
    • BMI and BMI SDS in childhood: annual increments and conditional change 

      Brannsether-Ellingsen, Bente; Eide, Geir Egil; Roelants, Mathieu; Bjerknes, Robert; Juliusson, Petur Benedikt (Taylor & Francis, 2016)
      Background: Early detection of abnormal weight gain in childhood may be important for preventive purposes. It is still debated which annual changes in BMI should warrant attention. Aim: To analyse 1-year increments of ...
      Journal article
    • Borderline values of troponin-T and high sensitivityC-reactive protein did not predict 2-year mortality inTnTpositive chest-pain patients, whereas brain natriureticpeptide did 

      Nilsen, Dennis W.T.; Mjelva, Øistein; Leon de la Fuente, Ricardo; Næsgaard, Patrycja; Pønitz, Volker; Andersen, Trygve Brugger; Grundt, Heidi; Staines, Harry; Nilsen, Stein Tore (Frontiers, 2015-04-08)
      Background: Troponin-T (TnT), high-sensitive C-reactive protein (hsCRP), and Brain Natriuretic Peptide (BNP) have been shown to be independent prognostic indicators of total and cardiac death during short- and long-term ...
      Journal article
    • The brain and brown fat 

      Contreras, Cristina; Gonzalez, Francisco; Fernø, Johan; Diéguez, Carlos; Rahmouni, Kamal; Nogueiras, Rubén; López, Miguel (Taylor & Francis, 2015-06-10)
      Brown adipose tissue (BAT) is a specialized organ responsible for thermogenesis, a process required for maintaining body temperature. BAT is regulated by the sympathetic nervous system (SNS), which activates lipolysis and ...
      Journal article
    • Burden of bloodstream infection in an area of Mid-Norway 2002-2013: A prospective population-based observational study 

      Mehl, Arne; Åsvold, Bjørn Olav; Lydersen, Stian; Paulsen, Julie; Solligård, Erik; Damås, Jan Kristian; Harthug, Stig; Edna, Tom-Harald (BioMed Central, 2017-03-11)
      Background: Studies from several countries indicate that the incidence and mortality of bloodstream infection (BSI) have been increasing over time. Methods: We studied the burden of disease and death related to BSI in a ...
      Journal article
    • Calprotectin (S100A8/A9) has the strongest association with ultrasound-detected synovitis and predicts response to biologic treatment: results from a longitudinal study of patients with established rheumatoid arthritis 

      Nordal, Hilde Haugedal; Brokstad, Karl Albert; Solheim, Magne; Halse, Anne-Kristine; Kvien, Tore Kristian; Hammer, Hilde Berner (BioMed Central, 2017-01-12)
      Background: Calprotectin (S100A8/A9 or MRP8/14) and S100A12 (leukocyte-derived proteins), interleukin 6 (IL-6) and vascular endothelial growth factor (VEGF) are markers of inflammation and angiogenesis. Ultrasound (US) is ...
      Journal article
    • Candidate locus analysis of the TERT–CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk 

      Carvajal-Carmona, Luis G.; O'Mara, Tracy A.; Painter, Jodie N.; Lose, Felicity A.; Dennis, Joe; Michailidou, Kyriaki; Tyrer, Jonathan P; Ahmed, Shahana; Ferguson, Kaltin; Healey, Catherine S.; Pooley, Karen; Beesley, Jonathan; Cheng, Timothy; Jones, Angela; Howarth, Kimberley; Martin, Lynn; Gorman, Maggie; Hodgson, Shirley; Wentzensen, Nicholas; Fasching, Peter A.; Hein, Alexander; Beckmann, Matthias W.; Renner, Stefan P.; Dörk, Thilo; Hillemanns, Peter; Durst, Matthias; Runnebaum, Ingo; Lambrechts, Dieter; Coenegrachts, Lieve; Schrauwen, Stefanie; Amant, Frederic; Winterhoff, Boris; Dowdy, Sean C.; Goode, Ellen L.; Teoman, Attila; Salvesen, Helga Birgitte; Trovik, Jone; Njølstad, Tormund Salvesen; Werner, Henrica Maria Johanna; Scott, Rodney J.; Ashton, Katie; Proietto, Tony; Otton, Geoffrey; Wersäll, Ofra; Mints, Miriam; Tham, Emma; Hall, Per; Czene, Kamila; Liu, Jianjun; Li, Jingmei; Hopper, John L.; Southey, Melissa C.; Ekici, Arif B.; Ruebner, Matthias; Johnson, Nichola; Peto, Julian; Burwinkel, Barbara; Marme, Frederik; Brenner, Hermann; Dieffenbach, Aida Karina; Meindl, Alfons; Brauch, Hiltrud; Lindblom, Annika; Depreeuw, Jeroen; Moisse, Matthieu; Chang-Claude, Jenny; Rudolph, Anja; Couch, Fergus J.; Olson, Janet E.; Giles, Graham G.; Bruinsma, Fiona; Cunningham, Julie M.; Fridley, Brooke L.; Børresen-Dale, Anne-Lise; Kristensen, Vessela N.; Cox, Angela; Swerdlow, Anthony J.; Orr, Nicholas; Bolla, Manjeet K.; Wang, Qin; Weber, Rachel Palmieri; Chen, Zhihua; Shah, Mitul; Pharoah, Paul D.P.; Dunning, Alison M.; Tomlinson, Ian; Easton, Douglas F.; Spurdle, Amanda B.; Thompson, Deborah J. (Springer, 2014-12-09)
      Several studies have reported associations between multiple cancer types and single-nucleotide polymorphisms (SNPs) on chromosome 5p15, which harbours TERT and CLPTM1L, but no such association has been reported with ...
      Journal article
    • Carbamylation of immunoglobulin abrogates activation of the classical complement pathway 

      Koro, Catalin; Bielecka, Ewa; Dahl-Knudsen, Anders; Enghild, Jan J; Scavenius, Carsten; Brun, Johan G; Binder, Veronika; Hellvard, Annelie; Bergum, Brith; Jonsson, Roland; Potempa, Jan; Blom, Anna M.; Mydel, Piotr Mateusz (Wiley, 2014-11)
      Post-translational modifications of proteins significantly affect their structure and function. The carbamylation of positively charged lysine residues to form neutral homoitrulline occurs primarily under inflammatory ...
      Journal article
    • Cardiotoxicity of Doxorubicin. A Study of Methods and Protective Interventions in Rat Models 

      Hole, Lisa Drange (The University of Bergen, 2015-03-13)
      Introduction: The clinical use of anthracyclines, like doxorubicin, is a double-edged sword. On one side, anthracyclines play an undisputed key role in the treatment of many neoplastic diseases. On the other side; ...
      Doctoral thesis
    • Carvedilol-enriched cold oxygenated blood cardioplegia improves left ventricular diastolic function after weaning from cardiopulmonary bypass 

      Dahle, Geir Olav; Salminen, Pirjo-Riitta; Moen, Christian Arvei; Eliassen, Finn; Nygreen, Else Loholdt; Kytö, Ville; Saukko, Pekka; Haaverstad, Rune; Matre, Knut; Grong, Ketil (Elsevier, 2016-08)
      Objectives: To investigate whether adding carvedilol, a nonselective β- and selective α1-receptor blocking agent with antioxidant properties, to oxygenated blood cardioplegia improves myocardial function after ...
      Journal article
    • CD64 as a potential biomarker in septic arthritis 

      Oppegaard, Oddvar; Skodvin, Brita; Halse, Anne-Kristine; Langeland, Nina (BioMed Central, 2013-06-19)
      Background Traditional inflammatory markers are generally unhelpful in discerning septic arthritis from inflammatory joint disease due to their lack of specificity. We wished to explore the discriminatory power of the novel ...
      Peer reviewedJournal article
    • Cell type specificity of neurovascular coupling in cerebral cortex 

      Uhlirova, Hana; Kiliç, Kivilcim; Tian, Peifang; Thunemann, Martin; Desjardins, Michèle; Saisan, Payam A.; Sakadžić, Sava; Ness, Torbjørn Vefferstad; Mateo, Celine; Cheng, Qun; Weldy, Kimberly L.; Razoux, Florence; Vandenberghe, Matthieu; Cremonesi, Jonathan A.; Ferri, Christopher G.L.; Nizar, Krystal; Sridhar, Vishnu B.; Steed, Tyler C.; Abashin, Maxim; Fainman, Yeshaiahu; Masliah, Eliezer; Djurovic, Srdjan; Andreassen, Ole Andreas; Silva, Gabriel A.; Boas, David A.; Kleinfeld, David; Buxton, Richard B.; Einevoll, Gaute; Dale, Anders; Devor, Anna (eLife, 2016-05-31)
      Identification of the cellular players and molecular messengers that communicate neuronal activity to the vasculature driving cerebral hemodynamics is important for (1) the basic understanding of cerebrovascular regulation ...
      Journal article
    • Cellular immune activity biomarker neopterin is associated hyperlipidemia: results from a large population-based study 

      Chuang, Shu-Chun; Boeing, Heiner; Vollset, Stein Emil; Midttun, Øivind; Ueland, Per Magne; Bueno-de-Mesquita, Bas; Lajous, Martin; Fagherazzi, Guy; Boutron-Ruault, Marie-Christine; Kaaks, Rudolf; Küehn, Tilman; Pischon, Tobias; Drogan, Dagmar; Tjønneland, Anne; Overvad, Kim; Quirós, J. Ramón; Agudo, Antonio; Molina-Montes, Esther; Dorronsoro, Miren; Huerta, José María; Barricarte, Aurelio; Khaw, Kay-Tee; Wareham, Nicholas J.; Travis, Ruth C.; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Masala, Giovanna; Agnoli, Claudia; Tumino, Rosario; Mattiello, Amalia; Peeters, Petra H.; Weiderpass, Elisabete; Palmqvist, Richard; Ljuslinder, Ingrid; Gunter, Marc; Lu, Yunxia; Cross, Amanda J.; Riboli, Elio; Vineis, Paolo; Aleksandrova, Krasimira (BioMed Central, 2016-02-25)
      Background: Increased serum neopterin had been described in older age two decades ago. Neopterin is a biomarker of systemic adaptive immune activation that could be potentially implicated in metabolic syndrome (MetS). ...
      Journal article
    • Challenges in diagnosing paediatric malaria in Dar es Salaam, Tanzania 

      Strøm, Gro Elizabeth Ann; Haanshuus, Christel Gill; Fataki, Maulidi; Langeland, Nina; Blomberg, Bjørn (BioMed Central, 2013-07-03)
      Background: Malaria is a major cause of paediatric morbidity and mortality. As no clinical features clearly differentiate malaria from other febrile illnesses, and malaria diagnosis is challenged by often lacking ...
      Journal article