Now showing items 158-177 of 448

    • Gel2DE - A software tool for correlation analysis of 2D gel electrophoresis data 

      Øye, Ola Kristoffer; Jørgensen, Katarina Mariann; Hjelle, Sigrun Margrethe; Sulen, André; Ulvang, Dag Magne; Gjertsen, Bjørn Tore (BioMed Central, 2013-07-06)
      Background: Two-dimensional gel electrophoresis (2DE) is a powerful technique for studying protein isoforms and their modifications. Existing commercial 2D image analysis tools rely on spot detection that limits analysis ...
      Journal article
    • Gender differences in childhood lyme neuroborreliosis 

      Tveitnes, Dag; Øymar, Knut (Hindawi publishing group, 2015-10-04)
      Background. Many neurological diseases show differences between genders. We studied gender differences in childhood Lyme neuroborreliosis (LNB) in an endemic area of Lyme borreliosis in Norway. Methods. In a population ...
      Journal article
    • Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949) 

      Davies, Gail; Armstrong, N; Bis, JC; Bressler, J; Chouraki, V; Giddaluru, Sudheer; Hofer, E; Ibrahim-Verbaas, CA; Kirin, M; Lahti, J; Van Der Lee, SJ; Le Hellard, Stephanie; Liu, T; Marioni, RE; Oldmeadow, C; Postmus, I; Smith, AV; Smith, JA; Thalamuthu, A; Thomson, R; Vitart, V; Wang, J; Yu, L; Zgaga, L; Zhao, W; Boxall, R; Harris, SE; Hill, WD; Liewald, DC; Luciano, M; Adams, H; Ames, D; Amin, N; Amouyel, P; Assareh, AA; Au, R; Becker, JT; Beiser, A; Berr, C; Bertram, L; Boerwinkle, E; Buckley, BM; Campbell, H; Corley, J; De Jager, PL; Dufouil, C; Eriksson, JG; Espeseth, Thomas; Faul, JD; Ford, I; Scotland, Generation; Gottesman, RF; Griswold, ME; Gudnason, V; Harris, TB; Heiss, G; Hofman, A; Holliday, EG; Huffman, J; Kardia, SLR; Kochan, N; Knopman, DS; Kwok, JB; Lambert, JC; Lee, T; Li, G; Li, SC; Loitfelder, M; Lopez, OL; Lundervold, Astri; Lundqvist, A; Mather, KA; Mirza, SS; Nyberg, L; Oostra, BA; Palotie, A; Papenberg, G; Pattie, A; Petrovic, K; Polasek, O; Psaty, BM; Redmond, P; Reppermund, S; Rotter, JI; Schmidt, H; Schuur, M; Schofield, PW; Scott, RJ; Steen, Vidar Martin; Stott, DJ; Van Swieten, JC; Taylor, KD; Trollor, J; Trompet, S; Uitterlinden, AG; Weinstein, G; Widen, E; Windham, BG; Jukema, JW; Wright, AF; Wright, MJ; Yang, Q; Amieva, H; Attia, JR; Bennett, DA; Brodaty, H; De Craen, AJM; Hayward, C; Ikram, MA; Lindenberger, U; Nilsson, LG; Porteous, DJ; Räikkönen, K; Rudan, I; Sachdev, PS; Schmidt, R; Schofield, PR; Srikanth, V; Starr, JM; Turner, ST; Weir, DR; Wilson, JF; Van Duijn, C; Launer, L; Fitzpatrick, AL; Seshadri, S; Mosley, TH; Deary, IJ; Reinvang, Ivar (Nature Publishing Group, 2015)
      General cognitive function is substantially heritable across the human life course from adolescence to old age. We investigated the genetic contribution to variation in this important, health- and well-being-related trait ...
      Journal article
    • Genetic diversity of circulating rotavirus strains in Tanzania prior to the introduction of vaccination 

      Moyo, Sabrina John; Blomberg, Bjørn; Hanevik, Kurt; Kommedal, Øyvind; Vainio, Kirsti; Maselle, Samwel Y.; Langeland, Nina (PLoS, 2014-05-20)
      Background: Tanzania currently rolls out vaccination against rotavirus-diarrhea, a major cause of child illness and death. As the vaccine covers a limited number of rotavirus variants, this study describes the molecular ...
      Journal article
    • Genetic relatedness and risk factor analysis of ampicillin-resistant and high-level gentamicin-resistant enterococci causing bloodstream infections in Tanzanian children 

      Aamodt, Håvard; Mohn, Stein Christian; Maselle, Samuel Y; Manji, Karim P.; Willems, Rob; Jureen, Roland; Langeland, Nina; Blomberg, Bjørn (BioMed Central, 2015-02-28)
      Background While enterococci resistant to multiple antimicrobials are spreading in hospitals worldwide, causing urinary tract, wound and bloodstream infections, there is little published data on these infections from ...
      Journal article
    • Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease 

      Lee, Jin H.; Cho, Michael H.; Hersh, Craig P.; McDonald, Merry-Lynn N.; Crapo, James D.; Bakke, Per; Gulsvik, Amund; Comellas, Alejandro P.; Wendt, Christine H.; Lomas, David A.; Kim, Victor; Silverman, Edwin K.; on behalf of the COPDGene and ECLIPSE Investigators (BioMed Central, 2014-09-21)
      Background: Chronic bronchitis (CB) is one of the classic phenotypes of COPD. The aims of our study were to investigate genetic variants associated with COPD subjects with CB relative to smokers with normal spirometry, and ...
      Journal article
    • Genetic variation in 117 myelination-related genes in schizophrenia: Replication of association to lipid biosynthesis genes 

      Stokowy, Tomasz; Polushina, Tatiana; Sønderby, Ida Elken; Karlsson, Robert; Giddaluru, Sudheer; Le Hellard, Stephanie; Bergen, Sarah E; Sullivan, Patrick F; Andreassen, Ole Andreas; Djurovic, Srdjan; Hultman, Christina M.; Steen, Vidar Martin (Nature Publishing Group, 2018-05-02)
      Schizophrenia is a serious psychotic disorder with high heritability. Several common genetic variants, rare copy number variants and ultra-rare gene-disrupting mutations have been linked to disease susceptibility, but there ...
      Journal article
    • A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry 

      Lutz, Sharon M; Cho, Michael H; Young, Kendra; Hersh, Craig P; Castaldi, Peter J; McDonald, Merry-Lynn; Regan, Elizabeth; Mattheisen, Manuel; DeMeo, Dawn L; Parker, Margaret; Foreman, Marilyn; Make, Barry J; Jensen, Robert L; Casaburi, Richard; Lomas, David A; Bhatt, Surya P; Bakke, Per; Gulsvik, Amund; Crapo, James D; Beaty, Terri H; Laird, Nan M; Lange, Christoph; Hokanson, John E; Silverman, Edwin K (BioMed Central, 2015-12-03)
      Background Pulmonary function decline is a major contributor to morbidity and mortality among smokers. Post bronchodilator FEV1 and FEV1/FVC ratio are considered the standard assessment of airflow obstruction. We performed ...
      Journal article
    • Getting personal: Can systems medicine integrate scientific and humanistic conceptions of the patient? 

      Vogt, Henrik; Ulvestad, Elling; Eriksen, Thor Eirik; Getz, Linn (Wiley, 2014-12)
      Rationale, aims and objectives The practicing doctor, and most obviously the primary care clinician who encounters the full complexity of patients, faces several fundamental but intrinsically related theoretical and practical ...
      Journal article
    • Giant right ventricular outflow tract thrombus in hereditary spherocytosis: a case report 

      Davidsen, Cedric; Larsen, Terje H.; Gerdts, Eva; Lønnebakken, Mai Tone (BioMed Central, 2016-04-26)
      Background: In hereditary spherocytosis with severe anemia, splenectomy is a recommended treatment. However, the spleen carries an important role both in immune function and coagulation. The increased risk of bacterial ...
      Journal article
    • Giardia-specific cellular immune responses in post-giardiasis chronic fatigue syndrome 

      Hanevik, Kurt; Kristoffersen, Einar; Mørch, Kristine; Rye, Kristin Paulsen; Sørnes, Steinar; Svärd, Staffan; Bruserud, Øystein; Langeland, Nina (BioMed Central, 2017-01-28)
      Background: The role of pathogen specific cellular immune responses against the eliciting pathogen in development of post-infectious chronic fatigue syndrome (PI-CFS) is not known and such studies are difficult to perform. ...
      Journal article
    • Global coronary artery plaque area is associated with myocardial hypoperfusion in women with non-ST elevation myocardial infarction 

      Eskerud, Ingeborg; Gerdts, Eva; Nordrehaug, Jan Erik; Lønnebakken, Mai Tone (Mary Ann Liebert, 2015-05)
      Background: Women with non-ST elevation myocardial infarction (NSTEMI) have similar extent of myocardial ischemia but less obstructive coronary artery disease (CAD) than their male counterparts. We tested the impact of ...
      Journal article
    • Global left ventricular load in asymptomatic aortic stenosis: covariates and prognostic implication (the SEAS trial) 

      Rieck, Åshild Elseth; Gerdts, Eva; Lønnebakken, Mai Tone; Bahlmann, Edda; Cioffi, Giovanni; Gohlke-Bärwolf, Christa; Ray, Simon; Cramariuc, Dana (BioMed Central, 2012-11-05)
      Introduction: Valvuloarterial impedance (Zva) is a measure of global (combined valvular and arterial) load opposing left ventricular (LV) ejection in aortic stenosis (AS). The present study identified covariates and tested ...
      Journal article
    • Global Lung Function Initiative 2012 reference equations for spirometry in the Norwegian Population 

      Langhammer, Arnulf; Johannessen, Ane; Holmen, Turid Lingaas; Melbye, Hasse; Stanojevic, Sanja; Lund, May Brit; Melsom, Morten Nissen; Bakke, Per S.; Quanjer, Philip (European Respiratory Society, 2016)
      We studied the fit of the Global Lung Function Initiative (GLI) all-age reference values to Norwegians, compared them with currently used references (European Community for Steel and Coal (ECSC) and Zapletal) and estimated ...
      Journal article
    • Glucocorticoid Treatment and Quality of Life in Addison’s disease 

      Øksnes, Marianne (The University of Bergen, 2014-06-06)
      Addison’s disease (AD) is rare and result in lack of the adrenal hormones cortisol, aldosterone and adrenal androgens. Despite conventional oral replacement therapy, mortality is increased and Health-Related Quality-of-life ...
      Doctoral thesis
    • Glycated hemoglobin and long-term prognosis in patients with suspected stable angina pectoris without diabetes mellitus: A prospective cohort study 

      Rebnord, Eirik Wilberg; Pedersen, Eva Kristine Ringdal; Strand, Elin; Svingen, Gard Frodahl Tveitevåg; Meyer, Klaus; Schartum-Hansen, Hall; Løland, Kjetil Halvorsen; Seifert, Reinhard; Ueland, Per Magne; Nilsen, Dennis W. T.; Nordrehaug, Jan Erik; Nygård, Ottar (Elsevier, 2015-05)
      Objective: Associations of glycated hemoglobin A1c (HbA1c) levels to incident coronary and cardiovascular events among non-diabetic patients with coronary artery disease are unclear. We investigated relations of HbA1c ...
      Journal article
    • GWAS-based pathway analysis differentiates between fluid and crystallized intelligence 

      Christoforou, Andrea; Espeseth, Thomas; Davis, G.; Fernandes, Carla P.D.; Giddaluru, Sudheer; Mattheisen, Manuel; Tenesa, A.; Harris, Sarah E.; Liewald, David C; Payton, Anthony; Ollier, W; Horan, M.; Pendleton, Neil; Haggarty, Paul; Djurovic, Srdjan; Herms, Stefan; Hoffman, P.; Cichon, Sven; Starr, John M; Lundervold, Astri; Reinvang, Ivar; Steen, Vidar Martin; Deary, Ian J; Le Hellard, Stephanie (2014-09)
      Cognitive abilities vary among people. About 40–50% of this variability is due to general intelligence (g), which reflects the positive correlation among individuals' scores on diverse cognitive ability tests. g is positively ...
      Journal article
    • HbA1c versus oral glucose tolerance test as a method to diagnose diabetes mellitus in vascular surgery patients 

      Hjellestad, Iren Drange; Astor, Marianne; Nilsen, Roy Miodini; Søfteland, Eirik; Jonung, Torbjørn (BioMed Central, 2013-05-25)
      Background: The diagnosis of diabetes mellitus (DM) is based on either fasting plasma glucose levels or an oral glucose tolerance test (OGTT). Recently, an HbA1c value of ≥48 mmol/mol (6.5%) has been included as ...
      Journal article
    • Headache in systemic lupus erythematosus and primary Sjogren's syndrome 

      Tjensvoll, Anne Bolette (The University of Bergen, 2016-11-09)
      Background Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease which can affect multiple organs. The central nervous system (CNS) is frequently affected, and headache, especially migraine, ...
      Doctoral thesis
    • Heat shock proteins and chronic fatigue in primary Sjögren's syndrome 

      Bårdsen, Kjetil; Mæland, Mari; Kvaløy, Jan Terje; Norheim, Katrine Brække; Jonsson, Grete; Omdal, Roald (Sage, 2016)
      Fatigue occurs frequently in patients with cancer, neurological diseases and chronic inflammatory diseases, but the biological mechanisms that lead to and regulate fatigue are largely unknown. When the innate immune system ...
      Journal article