• Blood neurofilament light concentration at admittance: a potential prognostic marker in COVID‑19 

      Aamodt, Anne Hege; Høgestøl, Einar August; Popperud, Trine Haug; Holter, Jan Cato; Dyrhol-Riise, Anne Ma; Tonby, Kristian; Stiksrud, Birgitte; Berge, Tone; Barratt-Due, Andreas; Aukrust, Pål; Heggelund, Lars; Blennow, Kaj; Zetterberg, Henrik; Harbo, Hanne Flinstad; Quist‑Paulsen, Else (Journal article; Peer reviewed, 2021)
      Objective To test the hypotheses that blood biomarkers for nervous system injury, serum concentrations of neurofilament light chain protein (NfL) and glial fibrillary acidic protein (GFAp) can serve as biomarkers for ...
    • Blood steroid levels predict survival in endometrial cancer and reflect tumor estrogen signaling 

      Forsse, David Erik; Tangen, Ingvild Løberg; Fasmer, Kristine Eldevik; Halle, Mari Kyllesø; Viste, Kristin; Almås, Bjørg; Bertelsen, Bjørn-Erik; Trovik, Jone; Haldorsen, Ingfrid S.; Krakstad, Camilla (Peer reviewed; Journal article, 2020-02)
      Objective Blood-based biomarkers are attractive due to ease of sampling and standardized measurement technology, reducing obstacles to clinical implementation. The objective of this study was to evaluate a clinically ...
    • Bloodlettings in Hemochromatosis Result in Increased Blood Lead (Pb) Concentrations 

      Yazdani, Mazyar; Distante, Sonia; Mørkrid, Lars; Ulvik, Rune Johan; Bolann, Bjørn Johan (Journal article; Peer reviewed, 2022)
      Hemochromatosis is a hereditary disorder, most often associated with mutations of the HFE (High FErrum) gene. If left untreated, it can result in severe parenchymal iron accumulation. Bloodletting is the mainstay treatment. ...
    • BLR1 and FCGR1A transcripts in peripheral blood associate with the extent of intrathoracic tuberculosis in children and predict treatment outcome 

      Jenum, Synne; Bakken, Rasmus; Sivakumaran, Dhanasekaran; Mukherjee, Aparna; Lodha, Rakesh; Singh, Sarman; Singh, Varinder; Haks, Marielle C.; Ottenhoff, Tom H.M.; Kabra, Sushil K.; Doherty, Timothy Mark; Ritz, Christian; Grewal, Harleen (Peer reviewed; Journal article, 2016-12-12)
      Biomarkers reflecting the extent of Mycobacterium tuberculosis-induced pathology and normalization during anti-tuberculosis treatment (ATT) would considerably facilitate trials of new treatment regimens and the identification ...
    • BMI and BMI SDS in childhood: annual increments and conditional change 

      Brannsether-Ellingsen, Bente; Eide, Geir Egil; Roelants, Mathieu; Bjerknes, Robert; Juliusson, Petur Benedikt (Peer reviewed; Journal article, 2016)
      Background: Early detection of abnormal weight gain in childhood may be important for preventive purposes. It is still debated which annual changes in BMI should warrant attention. Aim: To analyse 1-year increments of Body ...
    • Body mass index and childhood symptoms of depression, anxiety, and attention-deficit hyperactivity disorder: A within-family Mendelian randomization study 

      Hughes, Amanda M.; Sanderson, Eleanor; Morris, Tim; Ayorech, Ziada; Tesli, Martin Steen; Ask, Helga; Reichborn-Kjennerud, Ted; Andreassen, Ole; Magnus, Per Minor; Helgeland, Øyvind; Johansson, Stefan; Njølstad, Pål Rasmus; Davey Smith, George; Havdahl, Alexandra Karoline Saasen; Howe, Laura D.; Davies, Neil Martin (Journal article; Peer reviewed, 2022)
      Background: Higher BMI in childhood is associated with emotional and behavioural problems, but these associations may not be causal. Results of previous genetic studies imply causal effects but may reflect influence of ...
    • Bone mineral density and vitamin D in paediatric intestinal failure patients receiving home parenteral nutrition 

      Kvammen, Janne Anita; Thomassen, Rut Anne; Kjeserud, Christina; Sæland, Camilla; Godang, Kristin; Bollerslev, Jens; Thorsby, Per Medbøe; Juliusson, Petur Benedikt; Bentsen, Beint Sigmund; Henriksen, Christine (Journal article; Peer reviewed, 2020)
      Background & aims Patients with intestinal failure (IF) are dependent on long-term home parenteral nutrition (HPN) to ensure growth and development. The primary aim of the present study was to assess bone mineral density ...
    • Bones, blood and steel: How bioelectrical impedance analysis is affected by hip fracture and surgical implants 

      Steihaug, Ole Martin; Bogen, Bård Erik; Kristoffersen, Målfrid Holen; Ranhoff, Anette Hylen (Peer reviewed; Journal article, 2017)
      Introduction: Bioelectrical impedance analysis (BIA) is in widespread use, but there is uncertainty about its validity in patients with metal implants or after acute hip fracture and surgery. We aimed to investigate the ...
    • Boosting of cross-reactive and protection-associated T cells in children after live attenuated influenza vaccination 

      Mohn, Kristin Greve-Isdahl; Zhou, Fan; Brokstad, Karl Albert; Sridhar, Saranya; Cox, Rebecca Jane (Peer reviewed; Journal article, 2017-05)
      Background. Live attenuated influenza vaccines (LAIVs) stimulate a multifaceted immune response including cellular immunity, which may provide protection against newly emerging strains. This study shows proof of concept ...
    • Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology 

      van der Meer, Dennis; Shadrin, Alexey; O'Connell, Kevin Sean; Bettella, Francesco; Djurovic, Srdjan; Wolfers, Thomas; Alnæs, Dag; Agartz, Ingrid; Smeland, Olav Bjerkehagen; Melle, Ingrid; Sánchez, Jennifer Monereo; Linden, David E.J.; Dale, Anders; Westlye, Lars Tjelta; Andreassen, Ole; Frei, Oleksandr; Kaufmann, Tobias (Journal article; Peer reviewed, 2022)
      Background Schizophrenia is a complex polygenic disorder with subtle, distributed abnormalities in brain morphology. There are indications of shared genetic architecture between schizophrenia and brain measures despite ...
    • Borderline values of troponin-T and high sensitivityC-reactive protein did not predict 2-year mortality inTnTpositive chest-pain patients, whereas brain natriureticpeptide did 

      Nilsen, Dennis W.T.; Mjelva, Øistein; Leon de la Fuente, Ricardo; Næsgaard, Patrycja; Pønitz, Volker; Andersen, Trygve Brugger; Grundt, Heidi; Staines, Harry; Nilsen, Stein Tore (Peer reviewed; Journal article, 2015-04-08)
      Background: Troponin-T (TnT), high-sensitive C-reactive protein (hsCRP), and Brain Natriuretic Peptide (BNP) have been shown to be independent prognostic indicators of total and cardiac death during short- and long-term ...
    • Bounding the average causal effect in Mendelian randomisation studies with multiple proposed instruments: An application to prenatal alcohol exposure and attention deficit hyperactivity disorder 

      Diemer, Elizabeth W.; Havdahl, Alexandra; Andreassen, Ole A.; Munafò, Marcus R.; Njølstad, Pål Rasmus; Tiemeier, Henning; Zuccolo, Luisa; Swanson, Sonja A. (Journal article; Peer reviewed, 2023)
      Background As large-scale observational data become more available, caution regarding causal assumptions remains critically important. This may be especially true for Mendelian randomisation (MR), an increasingly popular ...
    • The brain and brown fat 

      Contreras, Cristina; Gonzalez, Francisco; Fernø, Johan; Diéguez, Carlos; Rahmouni, Kamal; Nogueiras, Rubén; López, Miguel (Peer reviewed; Journal article, 2015-06-10)
      Brown adipose tissue (BAT) is a specialized organ responsible for thermogenesis, a process required for maintaining body temperature. BAT is regulated by the sympathetic nervous system (SNS), which activates lipolysis and ...
    • ‘Brain fog’, guilt, and gratitude: experiences of symptoms and life changes in older survivors 6 months after hospitalisation for COVID-19 

      Heiberg, Kristi Elisabeth; Heggestad, Anne Kari Tolo; Jøranson, Nina; Lausund, Hilde; Breievne, Grete; Myrstad, Marius; Ranhoff, Anette Hylen; Walle-Hansen, Marte; Bruun-Olsen, Vigdis (Journal article; Peer reviewed, 2022)
      Purpose Several of those who have been infected with COVID-19 suffer from the post-COVID-19 condition months after the acute infection. Little is known about how older survivors have experienced the consequences and how ...
    • Brain plasticity after cognitive intervention in patients with mild cognitive impairment (MCI) evaluated by multimodal MR imaging in a randomized, controlled trial. 

      Hol, Haakon Ramsland (Doctoral thesis, 2022-12-16)
      Hjerneplasitisitet undersøkt hos individer med mild kognitiv svikt etter PC-administrert arbeidsminnetrening, evaluert med multimodal MRI teknikk, en randomisert kontroll studie. Formål: Hovedmålet med studien var å ...
    • Brain reactivity during aggressive response in women with premenstrual dysphoric disorder treated with a selective progesterone receptor modulator 

      Kaltsouni, Elisavet; Fisher, Patrick M.; Dubol, Manon; Hustad, Steinar; Lanzenberger, Rupert; Frokjaer, Vibe G.; Wikström, Johan; Comasco, Erika; Sundström-Poromaa, Inger (Journal article; Peer reviewed, 2021)
      Premenstrual dysphoric disorder (PMDD) is a psychiatric condition characterized by late luteal phase affective, cognitive, and physical impairment. The disorder causes significant suffering in about 5% of women in their ...
    • Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes 

      van der Meer, Dennis; Rokicki, Jaroslav; Kaufmann, Tobias; Còrdova Palomera, Aldo; Moberget, Torgeir; Alnæs, Dag; Bettella, Francesco; Frei, Oleksandr; Doan, Nhat Trung; Sønderby, Ida Elken; Smeland, Olav Bjerkehagen; Agartz, Ingrid; Bertolino, Alessandro; Bralten, Janita; Brandt, Christine Lycke; Buitelaar, Jan K.; Djurovic, Srdjan; van Donkelaar, Marjolein; Dørum, Erlend Solberg; Espeseth, Thomas; Faraone, Stephen V.; Fernandéz, Guillén; Fisher, Simon E.; Franke, Barbara; Haatveit, Beathe Christin; Hartman, Catharina A.; Hoekstra, Pieter J.; Håberg, Asta; Jönsson, Erik G.; Kolskår, Knut-Kristian; Le Hellard, Stephanie; Lund, Martina Jonette; Lundervold, Astri; Lundervold, Arvid; Melle, Ingrid; Monereo Sanchez, Jennifer; Norbom, Linn Christin Bonaventure; Nordvik, Jan Egil; Nyberg, Lars; Oosterlaan, Jaap; Papalino, Marco; Papassotiropoulos, Andreas; Pergola, Giulio; de Quervain, Dominique J.F.; Richard, Geneviéve´; Sanders, Anne-Marthe; Selvaggi, Pierluigi; Shumskaya, Elena; Steen, Vidar Martin; Tønnesen, Siren; Ulrichsen, Kristine Moe; Zwiers, Marcel P.; Andreassen, Ole Andreas; Westlye, Lars Tjelta (Peer reviewed; Journal article, 2018-10-02)
      The hippocampus is a heterogeneous structure, comprising histologically distinguishable subfields. These subfields are differentially involved in memory consolidation, spatial navigation and pattern separation, complex ...
    • Brainstem NTCP and dose constraints for carbon ion RT—Application and translation from Japanese to European RBE-weighted dose 

      Dale, Jon Espen; Molinelli, Silvia; Vischioni, Barbara; Vitolo, Viviana; Bonora, Maria; Magro, Giuseppe; Mairani, Andrea; Hasegawa, Azusa; Ohno, Tatsuya; Dahl, Olav; Valvo, Francesca; Fossati, Piero (Journal article; Peer reviewed, 2020)
      Background and Purpose: The Italian National Center of Oncological Hadrontherapy (CNAO) has applied dose constraints for carbon ion RT (CIRT) as defined by Japan’s National Institute of Radiological Sciences (NIRS). However, ...
    • BRCA1 Norway: comparison of classifcation for BRCA1 germline variants detected in families with suspected hereditary breast and ovarian cancer between different laboratories 

      Hovland, Henrikke Nilsen; Al-Adhami, Rafal; Ariansen, Sarah Louise; Van Ghelue, Marijke; Sjursen, Wenche; Anfinsen, Sigrid Lima; Bolstad, Marte; Berger, Amund Holte; Vetti, Hildegunn Høberg; Knappskog, Per Morten; Haukanes, Bjørn Ivar; Aukrust, Ingvild; Ognedal, Elisabet (Journal article; Peer reviewed, 2022)
      Pathogenic germline variants in Breast cancer susceptibility gene 1 (BRCA1) predispose carriers to hereditary breast and ovarian cancer (HBOC). Through genetic testing of patients with suspected HBOC an increasing number ...
    • Breastfed Infants With Spells, Tremor, or Irritability: Rule Out Vitamin B12 Deficiency 

      Ljungblad, Ulf Wike; Astrup, Henriette; Mørkrid, Lars; Hager, Helle Borgstrøm; Lindberg, Morten; Eklund, Erik A.; Monsen, Anne-Lise Bjørke; Rootwelt-Revheim, Terje; Tangeraas, Trine (Journal article; Peer reviewed, 2022)
      Background: In Norway, 5-10% of neonates and infants have biomarkers suggesting vitamin B12 deficiency from newborn screening tests and unselected clinical screening, respectively. Aims: The aims were to identify risk ...