Now showing items 1-6 of 6
Comparison of inflammatory markers in induced and spontaneous sputum in a cohort of COPD patients
(BioMed Central, 2014-11-15)
Background: Sputum induction is a non-invasive method for obtaining measurements of inflammation in the airways. Whether spontaneously sampled sputum can be a valid surrogate is unknown. The aim of this study was to compare ...
Alcohol at bedtime induces minor changes in sleep stages and blood gases in stable chronic obstructive pulmonary disease
Purpose/background: The purpose of this study is to explore the effect of a moderate dose of alcohol on sleep architecture and respiration in chronic obstructive pulmonary disease (COPD). Alcohol depresses both hypercapnic ...
The association of tidal EFL with exercise performance, exacerbations, and death in COPD
(Dove Press, 2017-07-26)
Background: Tidal expiratory flow limitation (EFLT) is frequently found in patients with COPD and can be detected by forced oscillations when within-breath reactance of a single-breath is ≥0.28 kPa·s·L-1. ...
Comparing microbiota profiles in induced and spontaneous sputum samples in COPD patients
(BioMed Central, 2017-08-29)
Background: Induced and spontaneous sputum are used to evaluate the airways microbiota. Whether the sputum types can be used interchangeably in microbiota research is unknown. Our aim was to compare microbiota in induced ...
Incidence of utilization- and symptom-defined COPD exacerbations in hospital- and population-recruited patients
Objectives: The objectives of this study were to estimate the impact of recruitment source and outcome definition on the incidence of acute exacerbations of COPD (AECOPD) and explore possible predictors of AECOPD. Patients ...
Participation in research bronchoscopy: a literature review
(Co-action publishing, 2016-02-03)
Bronchoscopy is the preferred method for collecting biological samples from the lower airways of subjects in clinical research. However, ensuring participation in clinical research can be challenging when the research ...