Now showing items 1-3 of 3
The multitude of molecular analyses in cancer: the opening of Pandora’s box
(BioMed Central, 2014-09-03)
The availability of large amounts of molecular data of unprecedented depth and width has instigated new paths of interdisciplinary activity in cancer research. Translation of such information to allow its optimal use in ...
Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
(Cold Spring Harbor Laboratory, 2015)
Mitochondrial genomes are separated from the nuclear genome for most of the cell cycle by the nuclear double membrane, intervening cytoplasm, and the mitochondrial double membrane. Despite these physical barriers, we show ...
Candidate locus analysis of the TERT–CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk
Several studies have reported associations between multiple cancer types and single-nucleotide polymorphisms (SNPs) on chromosome 5p15, which harbours TERT and CLPTM1L, but no such association has been reported with ...