Show simple item record

dc.contributor.authorØksnes, Marianneeng
dc.contributor.authorBensing, Sophieeng
dc.contributor.authorHulting, Anna-Lenaeng
dc.contributor.authorKämpe, Olleeng
dc.contributor.authorHackemann, Annikaeng
dc.contributor.authorMeyer, Gesineeng
dc.contributor.authorBadenhoop, Klauseng
dc.contributor.authorBetterle, Corradoeng
dc.contributor.authorParolo, Annaeng
dc.contributor.authorGiordano, Robertaeng
dc.contributor.authorFalorni, Albertoeng
dc.contributor.authorPapierska, Lucynaeng
dc.contributor.authorJeske, Wojciecheng
dc.contributor.authorKasperlik-Zaluska, Anna A.eng
dc.contributor.authorChatterjee, V. Krishna K.eng
dc.contributor.authorHusebye, Eystein Sverreeng
dc.contributor.authorLøvås, Kristianeng
dc.date.accessioned2014-08-22T07:28:17Z
dc.date.available2014-08-22T07:28:17Z
dc.date.issued2012-02eng
dc.identifier.issn0021-972Xeng
dc.identifier.urihttp://hdl.handle.net/1956/8317
dc.description.abstract<p>Context: Patients with Addison’s disease (AD) self-report impairment in specific dimensions on well-being questionnaires. An AD-specific quality-of-life questionnaire (AddiQoL) was developed to aid evaluation of patients.</p><p>Objective: We aimed to translate and determine construct validity, reliability, and concurrent validity of the AddiQoL questionnaire.</p><p>Methods: After translation, the final versions were tested in AD patients from Norway (n = 107), Sweden (n = 101), Italy (n = 165), Germany (n = 200), and Poland (n = 50). Construct validity was examined by exploratory factor analysis and Rasch analysis, aiming at unidimensionality and fit to the Rasch model. Reliability was determined by Cronbach’s coefficient- and Person separation index. Longitudinal reliability was tested by differential item functioning in stable patient subgroups. Concurrent validity was examined in Norwegian (n = 101) and Swedish (n = 107) patients.</p><p>Results: Exploratory factor analysis and Rasch analysis identified six items with poor psychometric properties. The 30 remaining items fitted the Rasch model and proved unidimensional, supported by appropriate item and person fit residuals and a nonsignificant X² probability. Crohnbach’s &#945;-coefficient 0.93 and Person separation index 0.86 indicate high reliability. Longitudinal reliability was excellent. Correlation with Short Form-36 and Psychological General Well-Being Index scores was high. A shorter subscale comprising eight items also proved valid and reliable. Testing of AddiQoL-30 in this large patient cohort showed significantly worse scores with increasing age and inwomencompared withmenbutnodifference between patients with isolatedADand those with concomitant diseases.</p><p>Conclusion: The validation process resulted in a revised 30-item AddiQoL questionnaire and an eight-item AddiQoL short version with good psychometric properties and high reliability.</p>en_US
dc.language.isoengeng
dc.publisherEndocrine Societyeng
dc.relation.ispartof<a href="http://hdl.handle.net/1956/8326" target="blank">Glucocorticoid Treatment and Quality of Life in Addison’s disease</a>eng
dc.titleQuality of Life in European Patients with Addison’s Disease: Validity of the Disease-Specific Questionnaire AddiQoLeng
dc.typeJournal articleeng
dc.rights.holderCopyright 2012 by The Endocrine Society
dc.type.versionpublishedVersioneng
bora.peerreviewedPeer reviewedeng
bora.journalTitleJournal of Clinical Endocrinology and Metabolismeng
bibo.volume97eng
bibo.issue2eng
bibo.pageStart568eng
bibo.pageEnd576eng
bibo.eissn1945-7197eng
bibo.doihttp://dx.doi.org/10.1210/jc.2011-1901eng
bora.accessRightsinfo:eu-repo/semantics/openAccesseng
dc.identifier.cristinID928478eng
dc.identifier.doi10.1210/jc.2011-1901
dcterms.isPartOfhttp://hdl.handle.net/1956/8326


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record