Blar i Faculty of Mathematics and Natural Sciences på forfatter "Fredman, David"
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Axis patterning by BMPs: cnidarian network reveals evolutionary constraints
Genikhovich, Grigory; Fried, Patrick; Prünster, M. Mandela; Schinko, Johannes B.; Gilles, Anna F.; Fredman, David; Meier, Karin; Iber, Dagmar; Technau, Ulrich (Peer reviewed; Journal article, 2015-03)BMP signaling plays a crucial role in the establishment of the dorso-ventral body axis in bilaterally symmetric animals. However, the topologies of the bone morphogenetic protein (BMP) signaling networks vary drastically ... -
Evolutionary turnover of mammalian transcription start sites
Frith, Martin C.; Ponjavic, Jasmina; Fredman, David; Kai, Chikatoshi; Kawai, Jun; Carninci, Piero; Hayashizaki, Yoshihide; Sandelin, Albin (Peer reviewed; Journal article, 2006-05-06)Alignments of homologous genomic sequences are widely used to identify functional genetic elements and study their evolution. Most studies tacitly equate homology of functional elements with sequence homology. This assumption ...