Now showing items 1-2 of 2

  • Coherent Conformational Degrees of Freedom as a Structural Basis for Allosteric Communication 

    Mitternacht, Simon; Berezovsky, Igor N. (Public Library of Science, 2011-12-08)
    Conformational changes in allosteric regulation can to a large extent be described as motion along one or a few coherent degrees of freedom. The states involved are inherent to the protein, in the sense that they are ...
    Peer reviewedJournal article
  • A geometry-based generic predictor for catalytic and allosteric sites 

    Mitternacht, Simon; Berezovsky, Igor N. (Oxford University Press, 2011)
    An important aspect of understanding protein allostery, and of artificial effector design, is the characterization and prediction of substrate- and effector-binding sites. To find binding sites in allosteric enzymes, many ...
    Journal articlePeer reviewed