• An amphipathic helix in Brl1 is required for nuclear pore complex biogenesis in S. cerevisiae 

      Kralt, Annemarie; Wojtynek, Matthias; Fischer, Jonas S.; Agote-Aran, Arantxa; Mancini, Roberta; Dultz, Elisa; Noor, Elad; Uliana, Federico; Tatarek-Nossol, Marianna; Antonin, Wolfram; Onishchenko, Evgeny; Medalia, Ohad; Weis, Karsten (Journal article; Peer reviewed, 2022)
      The nuclear pore complex (NPC) is the central portal for macromolecular exchange between the nucleus and cytoplasm. In all eukaryotes, NPCs assemble into an intact nuclear envelope (NE) during interphase, but the process ...
    • The Nuclear Pore Complex: Birth, Life, and Death of a Cellular Behemoth 

      Dultz, Elisa; Wojtynek, Matthias; Medalia, Ohad; Onishchenko, Evgeny (Journal article; Peer reviewed, 2022)
      Nuclear pore complexes (NPCs) are the only transport channels that cross the nuclear envelope. Constructed from ~500–1000 nucleoporin proteins each, they are among the largest macromolecular assemblies in eukaryotic cells. ...