Blar i Department of Biological Sciences på forfatter "Fladmark, Kari Espolin"

Viser treff 1-5 av 5

    • Algal toxin azaspiracid-1 induces early neuronal differentiation and alters peripherin isoform stoichiometry 

      Hjørnevik, Linda Veka; Frøyset, Ann Kristin; Grønset, Toril Anne; Rungruangsak-Torrissen, Krisna; Fladmark, Kari Espolin (Peer reviewed; Journal article, 2015-12-14)
      Azaspiracid-1 is an algal toxin that accumulates in edible mussels, and ingestion may result in human illness as manifested by vomiting and diarrhoea. When injected into mice, it causes neurotoxicological symptoms and ...

    • The N-terminal acetyltransferase Naa10 is essential for zebrafish development 

      Ree, Rasmus Moen; Myklebust, Line Merethe; Thiel, Puja; Foyn, Håvard; Fladmark, Kari Espolin; Arnesen, Thomas (Peer reviewed; Journal article, 2015-08-06)
      N-terminal acetylation, catalysed by N-terminal acetyltransferases (NATs), is among the most common protein modifications in eukaryotes and involves the transfer of an acetyl group from acetyl-CoA to the α-amino group of ...

    • Progressive Motor and Non-Motor Symptoms in Park7 Knockout Zebrafish 

      Chavali, Lakshmi Narasimha Murthy; Yddal, Ingeborg; Bifulco, Ersilia; Mannsåker, Simen; Røise, Dagne; Law, Jack Owen; Frøyset, Ann Kristin; Grellscheid, Sushma Nagaraja; Fladmark, Kari Espolin (Journal article; Peer reviewed, 2023)
      DJ-1 is a redox sensitive protein with a wide range of functions related to oxidative stress protection. Mutations in the park7 gene, which codes for DJ-1 are associated with early onset familial Parkinson’s disease and ...

    • Quantitative proteomics analysis of zebrafish exposed to sub-lethal dosages of β-methyl-amino-L-alanine (BMAA) 

      Frøyset, Ann Kristin; Khan, Essa Ahsan; Fladmark, Kari Espolin (Peer reviewed; Journal article, 2016-07-12)
      The non-protein amino acid β-methylamino-L-alanine (BMAA) is a neurotoxin present in microalgae and shown to accumulate in the food web. BMAA has been linked to the complex neurodegenerative disorder of Guam and to increased ...

    • Redox control of protein degradation 

      Pajares, Marta; Jiménez-Moreno, Natalia; Dias, Irundika H.K.; Debelec, Bilge; Vucetic, Milica; Fladmark, Kari Espolin; Basaga, Huveyda; Ribaric, Samo; Milisav, Irina; Cuadrado, Antonio (Peer reviewed; Journal article, 2015-12)
      Intracellular proteolysis is critical to maintain timely degradation of altered proteins including oxidized proteins. This review attempts to summarize the most relevant findings about oxidant protein modification, as well ...