• The Distribution of IgT mRNA+ Cells in the Gut of the Atlantic Salmon (Salmo salar L.) 

      Castro, Pedro Luis; Barac, Fran; Hansen, Tom Johnny; Fjelldal, Per Gunnar; Hordvik, Ivar; Bjørgen, Håvard; Koppang, Erling Olaf (Journal article; Peer reviewed, 2023)
      The newly discovered IgT+ B cell is thought to play a dominant role in mucosal immunity, but limited studies have examined its distribution in fish species, hindering our understanding of its function. This study investigated ...
    • Ectopic epithelial cell clusters in salmonid intestine are associated with inflammation 

      Bjørgen, Håvard; Koppang, Erling Olaf; Gunnes, Gjermund; Hordvik, Ivar; Moldal, Torfinn; Kaldhusdal, Magne; Dale, Ole Bendik (Peer reviewed; Journal article, 2018-06-11)
      An epizootic incidence of intestinal adenocarcinomas was reported in brood fish of Atlantic salmon (Salmo salar L.) in 2009. The condition was associated with a specific diet inducing enteritis and morphological changes. ...
    • The teleost polymeric Ig receptor counterpart in ballan wrasse (Labrus bergylta) differs from pIgR in higher vertebrates 

      Etayo, Angela; Bjørgen, Håvard; Koppang, Erling Olaf; Hordvik, Ivar (Journal article; Peer reviewed, 2022)
      As mucosal barriers in fish are the main sites where pathogens are encountered, mucosal immunity is crucial to avoid infection in the aquatic environment. In teleost fish, immunoglobulins are present in gut, gill and skin ...
    • A teleost structural analogue to the avian bursa of Fabricius 

      Løken, Oskar Mongstad; Bjørgen, Håvard; Hordvik, Ivar; Koppang, Erling Olaf (Peer reviewed; Journal article, 2019-12-26)
      The bursa of Fabricius is a primary and secondary lymphoid organ considered exclusively present in birds, and studies of this structure have been vital to our current understanding of the adaptive immune system of vertebrates. ...