Blar i Department of Biological Sciences på forfatter "Moosmann, Alexandra"
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Histone complement of a rapidly evolving chordate Oikopleura dioica: Developmental and sex-specific deployment of novel and universal histone variants and their posttranslational modifications
Moosmann, Alexandra (Doctoral thesis, 2010-10-22)The packaging of DNA into nucleosomes is a fundamentally conserved property of the eukaryotic nucleus which is evident in the conservation of histone sequences. Nevertheless, it is now clear that histone sequence variants ... -
Histone variant innovation in a rapidly evolving chordate lineage
Moosmann, Alexandra; Campsteijn, Coen; Jansen, Pascal W. T. C.; Nasrallah, Carole; Raasholm, Martina; Stunnenberg, Henk G; Thompson, Eric M. (Peer reviewed; Journal article, 2011-07-15)Background: Histone variants alter the composition of nucleosomes and play crucial roles in transcription, chromosome segregation, DNA repair, and sperm compaction. Modification of metazoan histone variant lineages occurs ...