Blar i Department of Informatics på forfatter "Grellscheid, Sushma Nagaraja"

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    • Deep conservation of ribosome stall sites across RNA processing genes 

      Chyzynska, Katarzyna; Labun, Kornel; Jones, Carl Matthew; Grellscheid, Sushma Nagaraja; Valen, Eivind Dale (Journal article; Peer reviewed, 2021)
      The rate of translation can vary depending on the mRNA template. During the elongation phase the ribosome can transiently pause or permanently stall. A pause can provide the nascent protein with the time to fold or be ...

    • FAIR+E pathogen data for surveillance and research: lessons from COVID-19 

      Neves, Aitana; Cuesta, Isabel; Hjerde, Erik; Klemetsen, Terje; Salgado, David; van Helden, Jacques; Rahman, Nadim; Fatima, Nazeefa; Karathanasis, Nestoras; Zmora, Pawel; Åkerström, Wolmar Nyberg; Grellscheid, Sushma Nagaraja; Waheed, Zahra; Blomberg, Niklas (Journal article; Peer reviewed, 2023)
      The COVID-19 pandemic has exemplified the importance of interoperable and equitable data sharing for global surveillance and to support research. While many challenges could be overcome, at least in some countries, many ...

    • Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner 

      Lagnado, Anthony; Leslie, Jack; Ruchaud-Sparagano, Marie-Helene; Victorelli, Stella; Hirsova, Petra; Ogrodnik, Mikolaj; Collins, Amy L; Vizioli, Maria Grazia; Habiballa, Leena; Saretzki, Gabriele; Evans, Shane A; Salmonowicz, Hanna; Hruby, Adam; Geh, Daniel; Pavelko, Kevin D; Dolan, David William Peter; Reeves, Helen L; Grellscheid, Sushma Nagaraja; Wilson, Colin H; Pandanaboyana, Sanjay; Doolittle, Madison; von Zglinicki, Thomas; Oakley, Fiona; Gallage, Suchira; Wilson, Caroline L; Birch, Jodie; Carroll, Bernadette; Chapman, James; Heikenwalder, Mathias; Neretti, Nicola; Khosla, Sundeep; Masuda, Claudio Akio; Tchkonia, Tamar; Kirkland, James L; Jurk, Diana; Mann, Derek A.; Passos, João F (Journal article; Peer reviewed, 2021)
      Cellular senescence is characterized by an irreversible cell cycle arrest as well as a pro-inflammatory phenotype, thought to contribute to aging and age-related diseases. Neutrophils have essential roles in inflammatory ...