Blar i Department of Informatics på emneord "Normal mode analysis"
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Binding Leverage as a Molecular Basis for Allosteric Regulation
(Peer reviewed; Journal article, 2011-09-15)Allosteric regulation involves conformational transitions or fluctuations between a few closely related states, caused by the binding of effector molecules. We introduce a quantity called binding leverage that measures the ... -
Coherent Conformational Degrees of Freedom as a Structural Basis for Allosteric Communication
(Peer reviewed; Journal article, 2011-12-08)Conformational changes in allosteric regulation can to a large extent be described as motion along one or a few coherent degrees of freedom. The states involved are inherent to the protein, in the sense that they are visited ... -
WEBnm@ v2.0: Web server and services for comparing protein flexibility
(Peer reviewed; Journal article, 2014-12-30)Background: Normal mode analysis (NMA) using elastic network models is a reliable and cost-effective computational method to characterise protein flexibility and by extension, their dynamics. Further insight into the ...