Browsing Department of Molecular Biology by Title
Now showing items 53-72 of 101
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Lifespan extension in a semelparous chordate Oikopleura dioica via developmental growth arrest : Roles of Target of Rapamycin (TOR) signaling and D type cyclins
(The University of Bergen, 2015-05-22)All living organisms experience ageing during the course of their lifespan. The science of ageing has emerged into an enthralling area of research. Our knowledge of the mechanisms of ageing and reproduction has been mainly ...Doctoral thesis -
Liver transcriptome analysis of Atlantic cod (Gadus morhua) exposed to PCB 153 indicates effects on cell cycle regulation and lipid metabolism
(BioMed Central, 2014-06-17)Background: Polychlorinated biphenyls (PCBs) are persistent organic pollutants (POPs) with harmful effects in animals and humans. Although PCB 153 is one of the most abundant among PCBs detected in animal tissues, its ...Journal article -
Long-range transcriptional regulation of vertebrate developmental genes and the evolution of genome architecture
(The University of Bergen, 2008-09-12)Despite the recent massive progress in production of vertebrate genome sequence data and large-scale efforts to completely annotate the human genome, we still have scant knowledge of the principles that built genomes in ...Doctoral thesis -
Massively parallel sequencing identifies a previously unrecognized X-linked disorder resulting in lethality in male infants owing to amino-terminal acetyltransferase deficiency
(BioMed Central, 2011-09-19)Conference object -
Maternal, paternal and temperature effects on otolith size of young herring (Clupea harengus L.) larvae: an experimental study
(The University of Bergen, 1997)Master thesis -
The Methylococcus capsulatus (Bath) Secreted Protein, MopE*, Binds Both Reduced and Oxidized Copper
(Public Library of Science (PLoS), 2012-08-20)Under copper limiting growth conditions the methanotrophic bacterium Methylococcus capsulatus (Bath) secrets essentially only one protein, MopE*, to the medium. MopE* is a copper-binding protein whose structure has been ...Journal articlePeer reviewed -
Modelling and expression of the extracellular domain of the human guanylyl cyclase C receptor
(The University of Bergen, 2011-09-14)The human guanylyl cyclase C receptor is the target for the heat-stable entero- toxin (STa) from enterotoxigenic Escherichia coli, which is responsible for more than 200 million episodes of diarrhea and 300,000 deaths ...Master thesis -
Molecular analysis of the development and function of the apical organ in the sea anemone Nematostella vectensis
(The University of Bergen, 2015-10-09)The shapes and patterns displayed across the animal kingdom exhibit great diversity, but at the same time similarities in their appearance can be observed. Scientist in the past have studied animal forms based on morphology. ...Doctoral thesis -
Multiskala sonarstudium av norsk vårgytende sild (Clupea harengus L.): vandringsmønster i slutten av beiteperioden
(The University of Bergen, 1999)Master thesis -
The N-terminal acetyltransferase Naa10 is essential for zebrafish development
(Portland Press Limited, 2015-08-06)N-terminal acetylation, catalysed by N-terminal acetyltransferases (NATs), is among the most common protein modifications in eukaryotes and involves the transfer of an acetyl group from acetyl-CoA to the α-amino group of ...Journal article -
N-terminal modifications of cellular proteins: the enzymes involved, their substrate specificities and biological effects
(Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, 2015-06-16)The vast majority of eukaryotic proteins are N-terminally modified by one or more processing enzymes. Enzymes acting on the very first amino acid of a polypeptide include different peptidases, transferases, and ligases. ...Journal article -
NAA10 mutation causing a novel intellectual disability syndrome with Long QT due to N-terminal acetyltransferase impairment
(Nature Publishing Group, 2015-11-02)We report two brothers from a non-consanguineous Irish family presenting with a novel syndrome characterised by intellectual disability, facial dysmorphism, scoliosis and long QT. Their mother has a milder phenotype including ...Journal article -
NatF Contributes to an Evolutionary Shift in Protein N-Terminal Acetylation and Is Important for Normal Chromosome Segregation
(Public Library of Science, 2011-07-07)N-terminal acetylation (N-Ac) is a highly abundant eukaryotic protein modification. Proteomics revealed a significant increase in the occurrence of N-Ac from lower to higher eukaryotes, but evidence explaining the underlying ...Peer reviewedJournal article -
Nervous necrosis virus (NNV) in farmed Norwegian fish species
(The University of Bergen, 2008-12-05)Doctoral thesis -
Nodavirus in farmed Atlantic cod Gadus morhua in Norway
(Inter-Research, 2007-09-14)Viral encephalopathy and retinopathy (VER) was diagnosed in 5 to 24 g sized farmed Atlantic cod Gadus morhua kept in sea cages at Parisvatn, Hordaland county, on the west coast of Norway. Moderate mortality (10 to 15%) ...Journal articlePeer reviewed -
Non-conserved C-terminal regions in the histone recognition module CW, determines specificity, stability and affinity towards monomethylated histone tails
(The University of Bergen, 2014-11-20)Histone modifications have an important role in epigenetic gene regulation and contribute to the cellular memory system. It has been well documented that certain patterns of histone modifications are associated with different ...Master thesis -
A novel human NatA N-alpha-terminal acetyltransferase complex: hNaa16p-hNaa10p (hNat2-hArd1)
(BioMed Central, 2009-05-29)Background: Protein acetylation is among the most common protein modifications. The two major types are post-translational Nε-lysine acetylation catalyzed by KATs (Lysine acetyltransferases, previously named HATs (histone ...Journal articlePeer reviewed -
De novo missense mutations in the NAA10 gene cause severe non-syndromic developmental delay in males and females
(Nature Publishing Group, 2015)Recent studies revealed the power of whole-exome sequencing to identify mutations in sporadic cases with non-syndromic intellectual disability. We now identified de novo missense variants in NAA10 in two unrelated individuals, ...Journal article -
On the chemistry, toxicology and genetics of the cyanobacterial toxins, microcystin, nodularin, saxitoxin and cylindrospermopsin
(MDPI, 2010-05-10)The cyanobacteria or “blue-green algae”, as they are commonly termed, comprise a diverse group of oxygenic photosynthetic bacteria that inhabit a wide range of aquatic and terrestrial environments, and display incredible ...Journal article -
Pesticides Induce Oxidative Stress in Zebrafish Embryo
(The University of Bergen, 2014-06-02)Aquaculture is an industry in rapid global growth. The increased demand and therefore production of aquacultural goods is bound to drain natural marine resources if fish are to continue being fed feeds based solely on ...Master thesis
