Now showing items 1-10 of 92
Dissecting the Transcriptional Regulatory Properties of Human Chromosome 16 Highly Conserved Non-Coding Regions
(Public Library of Science, 2011-09-13)
Non-coding DNA conservation across species has been often used as a predictor for transcriptional enhancer activity. However, only a few systematic analyses of the function of these highly conserved non-coding regions ...
Interactions between marine n-3 fatty acids and methylmercury in Atlantic salmon (Salmo salar)
(The University of Bergen, 2011-12-19)
Methylmercury (MeHg) is an environmental contaminant widely distributed in the aquatic environment. MeHg toxicity is characterized by a broad range of molecular cellular effects, often, if not always, induced through the ...
The cellular and molecular mechanisms of the notochord tubulogenesis in the marine invertebrate Ciona intestinalis
(The University of Bergen, 2013-01-18)
The biological tube is the fundamental structural design of most internal organs and body systems. Tubulogenesis involves a series of coordinated cellular processes, failure of any of which can cause severe dysfunctions ...
Nervous necrosis virus (NNV) in farmed Norwegian fish species
(The University of Bergen, 2008-12-05)
Separating NADH and NADPH fluorescence in live cells and tissues using FLIM
(Nature Publishing Group, 2014-05-29)
NAD is a key determinant of cellular energy metabolism. In contrast, its phosphorylated form, NADP, plays a central role in biosynthetic pathways and antioxidant defence. The reduced forms of both pyridine nucleotides are ...
Digestive protease activities, growth and feed utilisation in Atlantic salmon (Salmo salar L.)
(The University of Bergen, 2006-03-03)
The specific activities of trypsin and chymotrypsin in the pyloric caeca were investigated in individually labeled Atlantic salmon (Salmo salar L.). Photoperiod (natural or 24 h) and feed protein quality (two levels of ...
Histone complement of a rapidly evolving chordate Oikopleura dioica: Developmental and sex-specific deployment of novel and universal histone variants and their posttranslational modifications
(The University of Bergen, 2010-10-22)
The packaging of DNA into nucleosomes is a fundamentally conserved property of the eukaryotic nucleus which is evident in the conservation of histone sequences. Nevertheless, it is now clear that histone sequence variants ...
JASPAR 2010: the greatly expanded open-access database of transcription factor binding profiles
(Oxford University Press, 2010)
JASPAR (http://jaspar.genereg.net) is the leading open-access database of matrix profiles describing the DNA-binding patterns of transcription factors (TFs) and other proteins interacting with DNA in a sequence-specific ...
Comparing the intrinsic dynamics of multiple protein structures using elastic network models
Background: Elastic network models (ENMs) are based on the simple idea that a protein can be described as a set of particles connected by springs, which can then be used to describe its intrinsic flexibility using, for ...